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High Polymorphism In The K-Casein (Csn3) Gene From Wild And Domestic Caprine Species Revealed By Dna Sequencing, Oliver C. Jann, Eva-Maria Prinzenberg, Gordon Luikart, Ana Caroli, Georg Erhardt

Biological Sciences Faculty Publications

We assessed polymorphisms in exon IV of the k-casein gene (CSN3) in ten different breeds of domestic goat (Capra hircus) from three continents and in three related wild caprine taxa (Capra ibex, Capra sibirica and Capra aegagrus). Thirty-five DNA samples were sequenced within a 558 bp fragment of exon IV. Nine polymorphic sites were identified in domestic goat, including four new polymorphisms. In addition to four previously described polymorphic positions, a total of 13 polymorphisms allowed the identification of 13 DNA variants, corresponding to 10 protein variants. Because of conflicting nomenclature of these variants, we propose …