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Beyond Cell Adhesion: Exploring The Role Of Cadherin-11 Extracellular Processing By Adam Metalloproteases In Cranial Neural Crest Migration, Catherine D. Mccusker
Beyond Cell Adhesion: Exploring The Role Of Cadherin-11 Extracellular Processing By Adam Metalloproteases In Cranial Neural Crest Migration, Catherine D. Mccusker
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The migration of the cranial neural crest is an essential part of cranio-facial development in every vertebrate embryo. The cranial neural crest (CNC) is a transient population of cells that forms the lateral border of the anterior neural plate. In the tailbud stage Xenopus embryo, the neural crest cells delaminate from the neural tube, and undergo a large-scale migration from the dorsal to ventral region of the embryo. The CNC travels along distinct pathways, and populates specific regions of the embryos face. Once the CNC ceases migrating, it differentiates into a variety of tissues that are essential for cranio-facial structure …