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Life Sciences

University of Central Florida

HIM 1990-2015

Theses/Dissertations

Antimicrobial resistance; Cerium oxide nanoparticles; Minimum inhibitory concentration; Nanoparticles; Nanotechnology

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Cerium Oxide Nanoparticles For The Detection Of Antimicrobial Resistance, Alexander J. Noll May 2011

Cerium Oxide Nanoparticles For The Detection Of Antimicrobial Resistance, Alexander J. Noll

HIM 1990-2015

The rise of antimicrobial resistance demands the development of more rapid screening methods for the detection of antimicrobial resistance in clinical samples to both give the patient the proper treatment and expedite the treatment of patients. Cerium oxide nanoparticles may serve a useful role in diagnostics due to their ability to exist in a mixed valence state and act as either oxidizing agents or reducing agents. Considering that cerium oxide nanoparticles have been shown to shift in absorbance upon oxidation, a useful method of antimicrobial resistance detection could be based on the oxidation of cerium oxide nanoparticles. Herein, an assay …