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Household Food Expenditure Typology And Its Association With Child Stunting And Anemia In Indonesia, Ratu Ayu Dewi Sartika, Yusnita Yusnita, Winda M. Ningsih, Ririn Arminsih Wulandari Dds.,Dr, Siti A. Pujonarti, Fadila Wirawan Nov 2024

Household Food Expenditure Typology And Its Association With Child Stunting And Anemia In Indonesia, Ratu Ayu Dewi Sartika, Yusnita Yusnita, Winda M. Ningsih, Ririn Arminsih Wulandari Dds.,Dr, Siti A. Pujonarti, Fadila Wirawan

Kesmas

Stunting and anemia remain the coexisting nutritional problems among Indonesian children. However, evidence of household-level food expenditure and its association with child stunting and anemia is limited. This study aimed to observe the association between household food expenditure typology and child stunting and anemia in Indonesia. Data was obtained from the 2007 and 2014 Indonesia Family Life Survey (IFLS). The household food expenditure, child nutritional status, and anemia were observed in 2007 and 2014. Latent class analysis was taken to identify the food expenditure pattern. Binary logistic regression was applied to analyze the association between household food expenditure patterns and …


In Silico Modelling And Docking Simulation Of Egfr-Targeted Diphtheria Toxin Chimera With Various Targeting Moieties, Muhammad Afif Naufal Bmed, Benedictus Ansell Susanto Bmed, Talitha Dinda Gunawan Bmed, Azhar Ridha Lukman Bmed, Alifa Rahma Rizqina Bmed, Muhammad Misbahul Fuad Bmed Aug 2024

In Silico Modelling And Docking Simulation Of Egfr-Targeted Diphtheria Toxin Chimera With Various Targeting Moieties, Muhammad Afif Naufal Bmed, Benedictus Ansell Susanto Bmed, Talitha Dinda Gunawan Bmed, Azhar Ridha Lukman Bmed, Alifa Rahma Rizqina Bmed, Muhammad Misbahul Fuad Bmed

Indonesian Journal of Medical Chemistry and Bioinformatics

Introduction: Cancer is a major etiology of death worldwide due to high mortality and suboptimal medicine. However, an emerging field, targeted therapy enabled a more selective and effective therapeutic action. This article aims to analyze in-silico the hypothetical targeted therapy agent that is combinations of conjugate consisting of EGFR targeting moieties and diphtheria toxin (DT-390).

Method: Our novel peptide is a conjugate of a novel EGFR targeting peptide and DT-390, forming a chimera. The tertiary structure was predicted using AlphaFold 2.0. The best IDDT scoring and stereochemistry profiles were utilized. The HADDOCK2.4 webserver modelled the docking between our …


Avicennia Marina Mangrove Plant Mediated Selenium Nanoparticles And Their Therapeutic Activity Against Oral Pathogens And Other Biological Properties, Kannan Kamala, Pitchiah Sivaperumal, Dhanraj Ganapathy Aug 2024

Avicennia Marina Mangrove Plant Mediated Selenium Nanoparticles And Their Therapeutic Activity Against Oral Pathogens And Other Biological Properties, Kannan Kamala, Pitchiah Sivaperumal, Dhanraj Ganapathy

Journal of Dentistry Indonesia

In the last few decades nanoparticles are widely used in the control of many pathogenic bacteria, fungi, viruses, and cancer growth both in-vitro and in-vivo. A marine plant of Avicennia marina is widely used in traditional medicine for diabetes, inflammation and skin diseases. Objective: In general Avicennia marina has been used as a traditional medicine to treat various diseases and it has shown significant inhibition against various pathogen and the formation of free radicals. Also, the plant A.marina mediated selenium nanoparticles has therapeutic activity has promising to develop biocompatible new cost effective treatment for various oral diseases. Methods: …


The Prospect Of Indonesian Herbal As An Alternative Treatment For Covid-19 Patient: A Literature-Based Study, Hadi Sunaryo, Wahyu Hidayati Aug 2024

The Prospect Of Indonesian Herbal As An Alternative Treatment For Covid-19 Patient: A Literature-Based Study, Hadi Sunaryo, Wahyu Hidayati

Indonesian Journal of Medical Chemistry and Bioinformatics

Coronavirus disease 2019 (COVID-19) is a new disease caused by a novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The disease has several symptoms from mild to severe and could lead to death for comorbidities and the elderly. Therefore, the infections and mortality cases keep growing day by day, moreover many authorities are trying to suppress it by applying several health protocols, including medicines. Several studies were conducted on drug discovery from plants to cure the disease. The article aimed to do a narrative review about the prospect of JAMU becoming an alternative medicine to cure COVID-19 by mapping …


Metabolite Biomarker Discovery For Lung Cancer Using Machine Learning, Ariski Fajarido, Linda Erlina, Aryo Tedjo, Fadilah Fadilah, Wawaimuli Arozal Aug 2024

Metabolite Biomarker Discovery For Lung Cancer Using Machine Learning, Ariski Fajarido, Linda Erlina, Aryo Tedjo, Fadilah Fadilah, Wawaimuli Arozal

Indonesian Journal of Medical Chemistry and Bioinformatics

Lung cancer is the leading cause of cancer death worldwide. About 2.1 million lung cancer patients were diagnosed in 2018, accounting for about 11.6% of all newly diagnosed cancer cases. For lung cancer, blood is the first choice as a source of screening biomarker candidates. Blood biomarkers provide a snapshot of the patient's entire body, including the primary tumor, metastatic disease, immune response, and peritumoral stroma. However, sputum sampling, bronchial lavage or aspiration, exhaled breath (EB), and airway epithelial sampling represent unique samples for lung cancer and other airway cancers as potential sources for alternative biomarkers. Metabolites are products of …


Exploration Of Positive Deviance In Prevention Of Underweight In The Under-Five: A Qualitative Study On Low-Income Urban Families, Irwan Budiono, Lukman Fauzi, Dewi Sari Rochmayani Aug 2024

Exploration Of Positive Deviance In Prevention Of Underweight In The Under-Five: A Qualitative Study On Low-Income Urban Families, Irwan Budiono, Lukman Fauzi, Dewi Sari Rochmayani

Kesmas

Children under the age of five (the under-five) from low-income families are more vulnerable to experience underweight. This nutritional vulnerability is evident in the preliminary study, where 35.1% of the under-five experience underweight, and 28.48% are low-income families. This study aimed to explore Positive Deviance (PD) behaviors in preventing underweight among the under-five. The study applied a qualitative approach with a case study design. Data collection took place in July-August 2022, focusing on low-income families in the Gunung Brintik area. Data were collected through two focus group discussions, seven in-depth interviews, and five key informant interviews. Coding, subtheme, and theme …


Risk Factors For Cognitive Impairment In Adult Population Of Coastal Area: A Cross-Sectional Study In Maringkik Island, Indonesia, Herpan Syafii Harahap, Arina Windri Rivarti, Nurhidayati Nurhidayati, Fitriannisa Faradina Zubaidi, Dini Suryani, Legis Ocktaviana Saputri, Yanna Indrayana, Athalita Andhera, Muhammad Hilam, Abiyyu Didar Haq Aug 2024

Risk Factors For Cognitive Impairment In Adult Population Of Coastal Area: A Cross-Sectional Study In Maringkik Island, Indonesia, Herpan Syafii Harahap, Arina Windri Rivarti, Nurhidayati Nurhidayati, Fitriannisa Faradina Zubaidi, Dini Suryani, Legis Ocktaviana Saputri, Yanna Indrayana, Athalita Andhera, Muhammad Hilam, Abiyyu Didar Haq

Kesmas

Cognitive impairment is a medical condition commonly found in elderly populations, which can be due to vascular risk factors in patients. There remains limited data on risk factors for cognitive impairment among coastal region populations. This study aimed to investigate risk factors for cognitive impairment in the adult population of Maringkik Island, West Nusa Tenggara Province, Indonesia. Data collected were age, sex, education level, hypertension, antihypertensive treatment, diabetes mellitus, cigarette smoking, and body mass index status. A total of 114 participants were recruited using a consecutive sampling method. The participants’ cognitive function assessment used the Mini-Cog instrument. The cognitive impairment …


Molecular Insights Into Propylthiouracil As A Thyroid Peroxidase Inhibitor: A Computational Study Approach, Dwi Anita Suryandari, Luluk Yunaini, Hadi Sunaryo, Khaerunissa Anbar Istiadi, Irandi Putra Pratomo Jul 2024

Molecular Insights Into Propylthiouracil As A Thyroid Peroxidase Inhibitor: A Computational Study Approach, Dwi Anita Suryandari, Luluk Yunaini, Hadi Sunaryo, Khaerunissa Anbar Istiadi, Irandi Putra Pratomo

Indonesian Journal of Medical Chemistry and Bioinformatics

Thyroid peroxidase (TPO) is a crucial enzyme in the biosynthesis of thyroid hormones, catalyzing the iodination of tyrosine residues in thyroglobulin and the coupling of iodotyrosines to form thyroxine (T4) and triiodothyronine (T3). Propylthiouracil (PTU) is an antithyroid drug commonly used to manage hyperthyroidism by inhibiting TPO. Understanding the molecular interactions between TPO and PTU can provide insights into the inhibitory mechanisms and guide the design of more effective antithyroid medications. Objective: This study aims to elucidate the binding interactions between TPO and PTU through molecular docking, providing a detailed understanding of how PTU inhibits TPO activity. Methods: …


Foreword From Handling Editor - 12th Edition, Ahyahudin Sodri Jul 2024

Foreword From Handling Editor - 12th Edition, Ahyahudin Sodri

Journal of Environmental Science and Sustainable Development

We are delighted to present the 12th edition of JESSD, published in July 2024. We have selected nine of the best articles for this edition that related with topic of Environmental Science and Sustainable Development.


Exploring The Vulnerability Of Small-Scale Fisherfolks In Selected Barangays, Arlon Ponce Cadiz, Blesshelyn Guevarra Sanchez, Eden Vela Evangelista Jul 2024

Exploring The Vulnerability Of Small-Scale Fisherfolks In Selected Barangays, Arlon Ponce Cadiz, Blesshelyn Guevarra Sanchez, Eden Vela Evangelista

Journal of Environmental Science and Sustainable Development

Small-scale fisherfolks contributed to the livelihood and economic aspects of the fishery sector in the region. However, they are vulnerable regarding potential risks and threats caused by various conditions. This study explored the vulnerability of fifty-two small-scale fisherfolks selected from six barangays near Laguna's Northern West Bay, Philippines. The case study design guided the data collection from multiple sources, including survey questionnaires, unstructured interviews, and document analysis for triangulation and analysis of fisherfolks' exposure, sensitivity, and adaptive capacity. Results show that there are indicators that contribute to the vulnerability of fisherfolk in terms of exposure, which involves hydrometeorological hazards, water …


Social Entrepreneurship In Sustainable Development: Strengthening The Environmental Perspective, Muhammad Iqbal Rezky, Rasto Rasto Jul 2024

Social Entrepreneurship In Sustainable Development: Strengthening The Environmental Perspective, Muhammad Iqbal Rezky, Rasto Rasto

Journal of Environmental Science and Sustainable Development

Social entrepreneurship and sustainable development are closely related concepts. Social entrepreneurship applies entrepreneurial attributes with a focus on solving major social issues. The relationship between the two demonstrates the contribution of social entrepreneurship in addressing social and environmental problems, reducing poverty, and fostering sustainable economic growth. This research employs a bibliometric approach to analyze trends and patterns in 181 relevant articles published between 2015 and 2023. Findings indicate significant growth in research between 2019 and 2021. Countries and institutions such as Spain, the United States, and Universitat de Valencia stand out in these publications. The bibliometric analysis also reveals influential …


Natural Dye Of Indigofera Tinctoria For Textile Industry, Nor Isnaeni Dwi Arista, Sandra Arifin Aziz, Ani Kurniawati Jul 2024

Natural Dye Of Indigofera Tinctoria For Textile Industry, Nor Isnaeni Dwi Arista, Sandra Arifin Aziz, Ani Kurniawati

Journal of Environmental Science and Sustainable Development

The examination of sustainability within the textile industry necessitates an exploration of various environmental pollution issues. This study aims to tackle challenges in the synthetic dye industry by reviewing past research on textile dyeing, providing scientific insights, identifying patterns, and highlighting research gaps. It is hypothesized that the cultivation of Indigofera tinctoria with optimized NPK fertilization can significantly enhance its growth and yield, contributing to sustainable natural dye production. Using a mixed-methods approach, this study integrated bibliometric analysis of 1320 Scopus articles with field experiments. The bibliometric analysis, conducted with Vos Viewer software, identifies India and the United States as …


Market-Based Conservation Preference In The Forest Conservation Business, Rizaldy Yudhista Yudhista, Mahawan Karuniasa, Raldi Hendro Koestoer Jul 2024

Market-Based Conservation Preference In The Forest Conservation Business, Rizaldy Yudhista Yudhista, Mahawan Karuniasa, Raldi Hendro Koestoer

Journal of Environmental Science and Sustainable Development

Earth is on the verge of rising temperatures above 1.5˚ Celsius. Passing the limit of 1.5˚ Celsius is a significant risk in living on earth as it will increase the risks of natural disasters such as drought, flood, and storm. With forests capable of absorbing greenhouse gas (GHG) emissions, the need for forest conservation areas is increasing to keep the earth's temperature below 1.5˚ Celsius. The increase in demand is facing hurdles from its financial sustainability, as well as the stakeholder's paradigm, which is still seen as a forest from a direct economic perspective. Market-based initiatives (MBI) are a concept …


The Role Of Destination Image And Risk Perception On Interest In Revisiting Disaster-Prone Coastal Destinations, Fitri Rahmafitria, Heri Puspito Diyah Setiyorini, Purna Hindayani, Andrian Ramadhan Jul 2024

The Role Of Destination Image And Risk Perception On Interest In Revisiting Disaster-Prone Coastal Destinations, Fitri Rahmafitria, Heri Puspito Diyah Setiyorini, Purna Hindayani, Andrian Ramadhan

Journal of Environmental Science and Sustainable Development

The current trend in nature tourism has led to increased tourist visits to coastal areas, including destinations prone to disasters and previously exposed to tsunamis. This research, which aims to analyze the variables influencing tourists' desire to revisit disaster-prone areas, addresses a crucial and timely topic in tourism and disaster management. The research utilized a quantitative approach through a questionnaire-based survey of domestic tourists visiting the Pangandaran Beach Area in West Java, known for its susceptibility to tsunami disasters. The study involved 307 respondents who completed questionnaires between June and July 2023. Data analysis employed Partial Least Square – Structural …


Suitability Assessment Of Groundwater Quality For Drinking Purposes, Md. Zahidul Islam, M. G. Mostafa Jul 2024

Suitability Assessment Of Groundwater Quality For Drinking Purposes, Md. Zahidul Islam, M. G. Mostafa

Journal of Environmental Science and Sustainable Development

The groundwater status of Northwestern Bangladesh is a complex and challenging issue due to its arid and semi-arid climates, increasing population, overexploitation for domestic and irrigation purposes, lack of adequate rainfall, and limited water resources. The study aimed to assess the suitability and health risk of groundwater quality for drinking purposes. A total of one hundred groundwater samples were collected from shallow tubewells in two seasons, the monsoon (MON) and post-monsoon (POM), in northwestern Bangladesh (Ganges River basin) and analyzed using standard methods of analysis (Atomic adsorption spectrometry, UV-visible spectrometry, graphite, ion chromatography). The trends of predominant cations were Ca2+ …


Hubungan Antara Partisipasi Dalam Pengambilan Keputusan Kesehatan Perempuan Dengan Kehamilan Yang Tidak Diinginkan, Maria Anastasia Audrey, Sudarto Ronoatmodjo Jun 2024

Hubungan Antara Partisipasi Dalam Pengambilan Keputusan Kesehatan Perempuan Dengan Kehamilan Yang Tidak Diinginkan, Maria Anastasia Audrey, Sudarto Ronoatmodjo

Jurnal Epidemiologi Kesehatan Indonesia

Prevalensi Kehamilan Tidak Diinginkan (KTD) di Indonesia mencapai 10,7% pada tahun 2021. Pada wanita yang sudah menikah, keputusan kesehatan mencakup keputusan tentang kontrasepsi, yang idealnya melibatkan partisipasi perempuan bersama suaminya agar dapat dilakukan secara konsisten sehingga dapat mencegah KTD. Namun, data tahun 2017 menunjukkan proporsi pengambilan keputusan kesehatan perempuan yang dilakukan perempuan bersama suami hanya sebesar 43,7%. Penelitian ini bertujuan untuk mengetahui hubungan antara partisipasi bersama antara istri dan suami dalam pengambilan keputusan kesehatan perempuan dengan terjadinya KTD. Penelitian ini menggunakan desain studi crosssectional dengan menganalisis data Survei Demografi dan Kesehatan Indonesia tahun 2017. Kriteria inklusi sampel adalah perempuan yang …


A Comprehensive Scoping Review Of Snoezelen Room In Occupatioanal Therapy Best Practices, Muhammad Hidayat Sahid, Andriani Pratiwi, Mohamad Ghazali Masuri, Akehsan Dahlan Jun 2024

A Comprehensive Scoping Review Of Snoezelen Room In Occupatioanal Therapy Best Practices, Muhammad Hidayat Sahid, Andriani Pratiwi, Mohamad Ghazali Masuri, Akehsan Dahlan

Jurnal Epidemiologi Kesehatan Indonesia

Penelitian ini merupakan analisis komprehensif terhadap literatur, penelitian, dan sumber daya yang terkait dengan ruang Snoezelen, dengan tujuan menyajikan gambaran mengenai manfaat, praktik terbaik, dan potensi aplikasi dari lingkungan multi-sensorik ini. Tinjauan ini mensintesis dan menganalisis secara kritis informasi yang tersedia untuk berkontribusi pada pemahaman dan implementasi ruang Snoezelen bagi individu dengan kebutuhan beragam. Pencarian sistematis basis data elektronik, termasuk PubMed, PsycINFO, dan CINAHL, bersama dengan pencarian manual pada daftar referensi, mengidentifikasi 27 artikel relevan yang memenuhi kriteria inklusi. Proses seleksi yang ketat memastikan inklusi sumber yang berkualitas tinggi dan relevan. Metode ekstraksi dan sintesis data digunakan untuk mengidentifikasi tema …


Determinan Kegagalan Pengobatan Pada Pasien Tuberkulosis Sensitif Obat Dewasa Di Provinsi Jawa Tengah Tahun 2022, Elizabeth Wulandari, Sudarto Ronoatmodjo Jun 2024

Determinan Kegagalan Pengobatan Pada Pasien Tuberkulosis Sensitif Obat Dewasa Di Provinsi Jawa Tengah Tahun 2022, Elizabeth Wulandari, Sudarto Ronoatmodjo

Jurnal Epidemiologi Kesehatan Indonesia

Tuberkulosis (TB) adalah salah satu penyakit menular penyebab kematian tertinggi di dunia. Pada populasi pasien TB, terdapat banyak faktor yang dapat meningkatkan risiko kejadian yang tidak diharapkan dari pengobatan. Tujuan dari penelitian ini adalah untuk mengidentifikasi faktor-faktor yang berhubungan dengan kegagalan pengobatan pada pasien TB dewasa di Provinsi Jawa Tengah pada tahun 2022. Studi cross-sectional ini menganalisis data sekunder dari Sistem Informasi TB (SITB), menggunakan 14.542 sampel yang memenuhi kriteria inklusi dan eksklusi. Pasien TB berusia >15 tahun dan terdapat hasil pengobatan merupakan kriteria inklusi dalam penelitian ini. Kegagalan pengobatan merupakan variabel dependen dan variabel independennya adalah usia, jenis kelamin, …


Hubungan Campak Dengan Berat Badan Kurang Pada Anak Usia 24-59 Bulan Di Indonesia (Analisis Data Survei Status Gizi Indonesia 2021), Wiandhari Esa Gautami, Mondastri Korib Sudaryo Jun 2024

Hubungan Campak Dengan Berat Badan Kurang Pada Anak Usia 24-59 Bulan Di Indonesia (Analisis Data Survei Status Gizi Indonesia 2021), Wiandhari Esa Gautami, Mondastri Korib Sudaryo

Jurnal Epidemiologi Kesehatan Indonesia

Berat badan kurang atau underweight merupakan masalah gizi kurang yang diukur dengan perbandingan berat badan dan umur. Berat badan kurang pada balita akan mempengaruhi pertumbuhan fisik, kemampuan kognitif, meningkatkan risiko kematian dan penularan infeksi penyakit, salah satu penyakit infeksi yang umum terjadi pada balita adalah campak. Tujuan penelitian ini adalah mengetahui hubungan infeksi campak dengan berat badan kurang pada balita usia 24-59 bulan di Indonesia, dengan mengontrol variabel kovariat diantaranya jenis kelamin, usia, pendidikan ibu BBLR, riwayat TB paru, riwayat diare, riwayat ISPA, riwayat imunisasi campak dan pola makan. Studi ini menggunakan data Survei Status Gizi Indonesia (SSGI) di 34 …


Analisis Faktor Risiko Kejadian Malaria Di Kabupaten Batu Bara Tahun 2022, Fitri Wahyuni, Tri Yunis Miko Wahyono Jun 2024

Analisis Faktor Risiko Kejadian Malaria Di Kabupaten Batu Bara Tahun 2022, Fitri Wahyuni, Tri Yunis Miko Wahyono

Jurnal Epidemiologi Kesehatan Indonesia

Malaria adalah masalah kesehatan yang serius dan dapat berakibat fatal, terutama pada kelompok risiko tinggi seperti bayi, anak kecil, dan ibu hamil. Selain itu, malaria juga menyebabkan anemia dan menurunkan produktivitas tenaga kerja. Pada tahun 2010, sekitar 65% kabupaten di Indonesia merupakan daerah endemis malaria, dan sekitar 45% penduduk di daerah endemis berisiko tertular malaria. Di Kabupaten Batu Bara, kasus malaria meningkat dari tahun ke tahun. Penelitian ini bertujuan untuk mengetahui faktor-faktor risiko kejadian malaria. Penelitian ini menggunakan kasus-kontrol dan dilakukan pada Juni 2022 di Kabupaten Batu Bara dengan melibatkan responden berusia 12 tahun ke atas sebanyak 170 sampel. Indiividu …


Hubungan Komorbiditas Terhadap Kondisi Akhir Pasien Covid-19 Di Rsud Siti Fatimah Provinsi Sumatera Selatan, Dewie Suranti Jun 2024

Hubungan Komorbiditas Terhadap Kondisi Akhir Pasien Covid-19 Di Rsud Siti Fatimah Provinsi Sumatera Selatan, Dewie Suranti

Jurnal Epidemiologi Kesehatan Indonesia

Pada tahun 2021, Indonesia menempati peringkat pertama dengan kasus COVID-19 terbanyak di ASEAN. Angka kematian COVID-19 di Indonesia sebesar 3,4% dan peringkat ke-5 ditempati oleh Provinsi Sumatera Selatan. Penelitian terdahulu menunjukkan komorbiditas berkontribusi terhadap kematian pasien COVID-19 disertai usia dan jenis kelamin. Penelitian ini bertujuan untuk menganalisis peran usia, jenis kelamin, dan komorbiditas terhadap kondisi akhir pasien COVID-19 di RSUD Siti Fatimah. Metode penelitian menggunakan desain cohort retrospective dengan analisis cox regression pendekatan model proportional hazard. Penelitian ini menggunakan data sekunder yaitu rekam medik pasien terkonfirmasi COVID-19 di RSUD Siti Fatimah dari Januari-Desember 2021 berjumlah 928 pasien yang diambil dengan …


Optimizing The Expression Of Polyethylene Terephtalate Hydrolase-Encoding Synthetic Gene In Escherichia Coli Arctic Express (De3), Jocelyn Nataniel, Maria Ulfah, Dini Achnafani, Niknik Nurhayati, Gabriela Christy Sabbathini, Sri Rezeki Wulandari, Abinawanto Abinawanto, Is Helianti Jun 2024

Optimizing The Expression Of Polyethylene Terephtalate Hydrolase-Encoding Synthetic Gene In Escherichia Coli Arctic Express (De3), Jocelyn Nataniel, Maria Ulfah, Dini Achnafani, Niknik Nurhayati, Gabriela Christy Sabbathini, Sri Rezeki Wulandari, Abinawanto Abinawanto, Is Helianti

Makara Journal of Science

The waste of polyethylene terephthalate (PET) plastic waste in Indonesia is a pressing concern due to its slow degradation and potential environmental damage. One promising solution is to utilize polyethylene terephthalate hydrolase from Ideonella sakaiensis (IsPETase), an enzyme that specifically degrades PET. However, inducing the expression of IsPETase synthetic gene in Escherichia coli BL21 (DE3) has been challenging because much of it remains insoluble. This study aimed to express IsPETase in E. coli Arctic Express (DE3) and optimize the conditions to enhance its production. First, pET22b(+)pelB-IsPETase was inserted into E. coli Arctic Express (DE3). The …


Pengaruh Promosi Kesehatan Melalui Media Sosial Whatsapp Terhadap Pemahaman Ibu Tentang Menu Mpasi Bergizi Di Kabupaten Sumedang, Dini Afriani, Witri Dewi Mentari, Ziana Azahra Jun 2024

Pengaruh Promosi Kesehatan Melalui Media Sosial Whatsapp Terhadap Pemahaman Ibu Tentang Menu Mpasi Bergizi Di Kabupaten Sumedang, Dini Afriani, Witri Dewi Mentari, Ziana Azahra

Jurnal Epidemiologi Kesehatan Indonesia

Masyarakat menggunakan media sosial sebagai platform untuk berbagi teks, gambar, suara, dan video satu sama lain dan juga dengan pelaku bisnis. Studi ini meneliti pengetahuan ibu tentang menu makanan tambahan yang khas dan kaya nutrisi dengan menggunakan media sosial Whatsapp dan teknik video/teks dalam kelompok. Tujuannya adalah untuk mengetahui dampak dari promosi kesehatan melalui media sosial Whatsapp terhadap pemahaman para ibu mengenai menu makanan tambahan yang khas dan kaya gizi untuk bayi baru lahir. Penelitian ini menggunakan desain One Group Pre-test Post-test untuk pengujian sebelum dan sesudahnya. Dalam penelitian ini, ibu dari anak-anak berusia 6 hingga 24 bulan digunakan. Ibu …


Degradation Of Chlorpyrifos Residue On Tropical Inceptisol Soil With Indigenous Bacteria Treatment, Asep Kurnia, Hidayatuz Zu`Amah, Baiq Nunung Sulastri, Ria Fauriah Makmur Jun 2024

Degradation Of Chlorpyrifos Residue On Tropical Inceptisol Soil With Indigenous Bacteria Treatment, Asep Kurnia, Hidayatuz Zu`Amah, Baiq Nunung Sulastri, Ria Fauriah Makmur

Makara Journal of Science

The use of soil microbes is one of the most effective methods for degrading pesticide residue in soil. Microbes can accelerate the degradation of persistent pollutants including chlorpyrifos in soil. This research aims to find soil bacteria with the greatest potential to degrade chlorpyrifos residue in tropical inceptisol soil and determine its degradation index (DI). The soil used in this experiment was collected from agricultural fields in the districts of Demak, Central Java Province, Indonesia. The experiment was performed using factorial randomize complete block design composed of two factors and four replications. The first factors were made up of two …


Limonoids Isolated From Chisocheton Pentandrus (Meliaceae) Stembarks And Its Cytotoxicity Towards Mcf-7 Breast Cancer Cell Line, Dudi Runadi, Intan Hawina Anjari, Purnama Purnama, Nurlelasari Nurlelasari, Desi Harneti, Tri Mayanti, Harizon Harizon, Ace Tatang Hidayat, Supriatno Salam, Mohamad Nurul Azmi, Unang Supratman Jun 2024

Limonoids Isolated From Chisocheton Pentandrus (Meliaceae) Stembarks And Its Cytotoxicity Towards Mcf-7 Breast Cancer Cell Line, Dudi Runadi, Intan Hawina Anjari, Purnama Purnama, Nurlelasari Nurlelasari, Desi Harneti, Tri Mayanti, Harizon Harizon, Ace Tatang Hidayat, Supriatno Salam, Mohamad Nurul Azmi, Unang Supratman

Makara Journal of Science

Chisocheton is a large source of limonoids with various pharmacological effects, such as antiviral, antibacterial, antimalarial, antifungal, and cytotoxic activities. This study aimed to isolate, elucidate, and evaluate the cytotoxicity of limonoids from C. pentandrus stembarks. Isolation was carried out using various separation methods including extraction and column chromatography. Spectral data were analyzed by FT-IR, UV, DEPT 135°, 1H, 13C-NMR, and HRTOF-MS and compared with those previously reported to determine the chemical structure.The obtained limonoids were lasiocarpine (1), lasiocarpine B (2), pentandricine (3), and 16β-hydroxydysobinin (4); all of which were …


Innovation In Bioinformatics: Recent Tools, Database And Involvement Of Artificial Intelligence, Aziz Ahmed, Mohd Shuaib, Abdulbasid Banga, Rizwan Ahmad May 2024

Innovation In Bioinformatics: Recent Tools, Database And Involvement Of Artificial Intelligence, Aziz Ahmed, Mohd Shuaib, Abdulbasid Banga, Rizwan Ahmad

Indonesian Journal of Medical Chemistry and Bioinformatics

Bioinformatics has evolved in recent years into a crucial subject and a well-liked research area that is interconnected with many approaches and disciplines. The capacity of bioinformatics and its approaches to tackle challenging biological problems and promote research and development. There are various tools and database which are used in bioinformatics. AI is the capacity of a computational system to carry out various activities associated with intellectual beings and as a computer system's imitation of human intelligence processes. The bioinformatics applications with artificial intelligence have the capacity to annotate the data in the direction of logical conclusions. By combining AI …


Physico-Chemical, Organoleptic, And Antioxidant Properties Of Black Soybean Flour (Glycine Soja (L.) Merrit) Flakes With The Addition Of Bangle (Zingiber Purpureum Roxb.), Ika Dyah Kumalasari, Nurkhasanah Nurkhasanah, Sepitriani Sepitriani May 2024

Physico-Chemical, Organoleptic, And Antioxidant Properties Of Black Soybean Flour (Glycine Soja (L.) Merrit) Flakes With The Addition Of Bangle (Zingiber Purpureum Roxb.), Ika Dyah Kumalasari, Nurkhasanah Nurkhasanah, Sepitriani Sepitriani

Pharmaceutical Sciences and Research

Flakes are products that are generally made from cereals. In this study, we are interested to use black soybean (Glycine soja (L) Merrit) and bangle (Zingiber purpureum Roxb.) as flakes ingredients. Black soybeans have high antioxidant components, while bangle contains high antioxidant and fiber components, which enables it to capture free radicals. This study aimed to find the most favorable formula with good physical, chemical, and organoleptic characteristics, which also has the highest antioxidant activity. We used the Completely Randomized Design (CRD) method and the variation of formulation used was the ratio of black soybean flour to bangle …


Relationship Of Stress And Other Factors With Emotional Eating Among Adolescents In Depok, Muthia Syifa Rahmadina, Asih Setiarini Apr 2024

Relationship Of Stress And Other Factors With Emotional Eating Among Adolescents In Depok, Muthia Syifa Rahmadina, Asih Setiarini

Indonesian Journal of Public Health Nutrition (IJPHN)

Emotional eating is an overeating behavior as a coping mechanism for negative emotions that emerges in adolescence. Emotional eating causes obesity, eating disorders, and non-communicable diseases. This study aims to determine the relationship between stress, body image, peer influence, parental rearing styles, social media use, sex, sleep quality, and emotion regulation with emotional eating among adolescents at senior high school in Depok. This cross-sectional quantitative study was conducted online in March 2022. The samples were grade X and XI students from senior high school in Depok who were chosen by using purposive sampling techniques (n=174). Chi X2 test and Mann …


The Differences In Maternal Clean And Healthy Living Behavior In The Incidence Of Stunting In Yogyakarta, Shafa Ramadhita, Anindhita Syahbi Syagata, Nor Eka Noviani Apr 2024

The Differences In Maternal Clean And Healthy Living Behavior In The Incidence Of Stunting In Yogyakarta, Shafa Ramadhita, Anindhita Syahbi Syagata, Nor Eka Noviani

Indonesian Journal of Public Health Nutrition (IJPHN)

An indirect cause of stunting is maternal behavior. Moreover, good nutritional knowledge relates to good nutritional behaviors. Maternal clean and Healthy Living Behavior (PHBS) in daily life can reduce the risk of infectious diseases and be role models for children in implementing their future health behavior. The study aims to investigate the differences in PHBS of mothers in the incidence of stunting ages 24-59 months in the Minggir Primary Health Center working area. The cross-sectional approach of this research was conducted from March to April 2023. The subjects of this study were 69 respondents selected by cluster random sampling. The …


Factors Associated With Wasting In Toddlers Aged 6 – 59 Months At Cimpaeun Village, Depok City, West Java, Indonesia In 2023, Early Vici Azmia, Triyanti Triyanti Apr 2024

Factors Associated With Wasting In Toddlers Aged 6 – 59 Months At Cimpaeun Village, Depok City, West Java, Indonesia In 2023, Early Vici Azmia, Triyanti Triyanti

Indonesian Journal of Public Health Nutrition (IJPHN)

The prevalence of wasting under five in Indonesia in 2022 is 7.7%; according to WHO, this wasting problem is a serious public health problem. Wasting is a nutritional problem in toddlers that has an impact on morbidity and mortality. The research objective was to determine the factors associated with wasting in toddlers aged 6–59 months in Cimpaeun Village in 2023. The dependent variable is wasting, and the independent variables are birth weight, history of fever, diarrhea, acute respiratory infection, energy intake, carbohydrate intake, protein intake, fat intake, mother’s age, pregnancy, mother’s education level, mother’s nutritional knowledge, and family income. This …