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Life Sciences

The University of Maine

Theses/Dissertations

2019

Antibiotic alternatives

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Innovative Resources In Small Ruminant Health, Sarah Paluso May 2019

Innovative Resources In Small Ruminant Health, Sarah Paluso

Electronic Theses and Dissertations

Caseous lymphadenitis (CL) is a chronic bacterial infection caused by Corynebacterium pseudotuberculosis (C. pseudoTB) that affects small ruminants. This disease has a worldwide prevalence and results in significant economic losses to the sheep and goat industries. Antibiotics have had limited success in treating CL, due to the difficulty of penetrating the dry, thick-walled abscesses that characterize this disease. Essential oils are complex bioactive compounds that have been increasingly explored as sources of antimicrobial activity. Due to the nature of these oils, tissue and wood penetration may be possible, enabling topical and environmental treatment (e.g.; disinfectants of farm surfaces, such as …