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Life Sciences

Louisiana State University

Theses/Dissertations

2012

Altrenogest

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Evaluation Of Methods For Suppressing Estrus And Ovulation In Mares: Sustained Release Injections Of Altrenogest Versus Deslorelin Acetate, Thomas J. Stevens Jan 2012

Evaluation Of Methods For Suppressing Estrus And Ovulation In Mares: Sustained Release Injections Of Altrenogest Versus Deslorelin Acetate, Thomas J. Stevens

LSU Master's Theses

Two experiments assessed the potential of altrenogest, an artificial progestogen, and deslorelin acetate, a gonadotropin-releasing hormone (GnRH) agonist, for suppressing estrus and ovulation in cyclic mares. In the first experiment, mares were administered a luteolytic dose of prostaglandin-F2á on d 6 of diestrus, and were then treated with 1 of 3 formulations of altrenogest in slow-release vehicle (6 mares/group): 1) Biorelease altrenogest LA150 (225 mg total as a 1.5 mL injection); 2) Biorelease altrenogest LA225 (225 mg total as a 1.0 mL injection); or 3) Biorelease altrenogest LA225 (450 mg total as a 2.0 mL injection). Six control mares received …