Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Entire DC Network
Survey Of Microbial Urea Degrader Diversity In Two Freshwater Ecosystems: Lake Shenandoah And The Shenandoah River, Naomi E. Gilbert
Survey Of Microbial Urea Degrader Diversity In Two Freshwater Ecosystems: Lake Shenandoah And The Shenandoah River, Naomi E. Gilbert
Senior Honors Projects, 2010-2019
One of the primary drivers of cyanobacterial harmful algal blooms (cHABs) in freshwater systems is nutrient loading, particularly of nitrogen and phosphorus. There has been an increased focus on assessing the role of nitrogen (N) in freshwater lakes and rivers that suffer cHABs. Urea, a widely-used, N-rich fertilizer, is a source of interest due to its abundance in freshwater ecosystems, primarily caused by anthropogenic nutrient loading. While recent work has shown that cHAB population succession may favor the toxic cyanobacterium Microcystis in urea-rich waters, the diversity of the associated bacterial community capable of degrading urea has yet to be determined. …
The Antimicrobial And Biofilm Disruption Activity Of Novel Amphiphiles, Elizabeth A. Rogers
The Antimicrobial And Biofilm Disruption Activity Of Novel Amphiphiles, Elizabeth A. Rogers
Masters Theses, 2010-2019
Antibiotic resistant infections are responsible for approximately 23,000 deaths every year in the United States alone. The formation of bacterial biofilms makes resistant bacteria difficult to eliminate completely using chemical treatment. Therefore, novel antimicrobial compounds such as amphiphiles are essential to slow or stop the spread of resistant bacteria. Several novel series of amphiphiles were synthesized, and discrete aspects of their chemical structure were altered to investigate the relationship between structure and antibacterial activity. Minimum inhibitory concentration (MIC) assays were used to measure antibacterial activity against two Gram-negative and five Gram-positive bacteria, and the most effective compounds were tested for …