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Doxycycline Resistance In Plasmodium Falciparum Linked To Single Nucleotide Polymorphisms In The Plasmodium Falciparum Apicoplast Small Subunit Ribosomal Rna (Pfssrrna) Gene, Amanda Wasko Apr 2016

Doxycycline Resistance In Plasmodium Falciparum Linked To Single Nucleotide Polymorphisms In The Plasmodium Falciparum Apicoplast Small Subunit Ribosomal Rna (Pfssrrna) Gene, Amanda Wasko

Scholarly and Creative Works Conference (2015 - 2021)

Plasmodium falciparum, a protozoan parasite known as malaria, widely impacts human health; thus antimalarial drug investigations are critical. Doxycycline is a commonly used antimalarial prophylactic, but its mechanism of action is unclear. In prokaryotes, doxycycline works as an antibacterial by disrupting protein translation via the small subunit ribosome. Interestingly, P. falciparum has a small subunit ribosome of prokaryotic origins in the apicoplast, a plastid-like organelle. Therefore, we hypothesized that doxycycline works in P. falciparum by inhibiting protein synthesis via the small subunit ribosomal RNA and that mutations in the gene encoding the P. falciparum apicoplast small subunit ribosomal RNA …


Movies With Meaning: Crossing Disciplines In Cinema, Ashley Cotter Apr 2016

Movies With Meaning: Crossing Disciplines In Cinema, Ashley Cotter

Scholarly and Creative Works Conference (2015 - 2021)

One might not realize that blockbuster movies can be used as an educational tool in the classroom setting to enhance the learning process. While these types of movies are not crafted as pedagogical tools, like animated, demonstrative video clips, there is educational value to be found in them. In more recent years, this is a practice that has been used in many classrooms. However, it is within the social sciences primarily that these blockbuster films are used to augment the understanding of concepts. Big films are rarely, if ever, used in the hard sciences to provide examples of concepts. How …


Analysis Of The Diets Of The Northern Spotted Owl And Barred Owl, Valeria Briones Apr 2015

Analysis Of The Diets Of The Northern Spotted Owl And Barred Owl, Valeria Briones

Scholarly and Creative Works Conference (2015 - 2021)

The Northern Spotted Owl, a once thriving species is now a threatened species and on the verge of endangerment. The Barred Owl, a species native to the eastern United States over the past few centuries has expanded its range into that of the Northern Spotted Owl, causing a major threat to the Northern Spotted Owl Populations. This paper is a synthesis of the existing literature of the diets of the Northern Spotted Owl and Barred Owl individually as well as in areas in which they occur sympatrically. With this summary of literature, the reader can gain an understanding of the …