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Biomechanical Testing Of Salter-Harris Fractures Type I And Ii In The Distal Femur And Proximal Tibia, Margeaux Rogers
Biomechanical Testing Of Salter-Harris Fractures Type I And Ii In The Distal Femur And Proximal Tibia, Margeaux Rogers
All Theses
Salter-Harris fractures of the proximal tibia and distal femur are common in pediatric patients that present to orthopedic surgeons. Salter-Harris type I fractures are characterized by breaks that extend only through the physis while Salter-Harris II fractures are the most common, accounting for 85% of Salter-Harris fractures, and extend past the growth plate, exiting through the metaphyseal bone1. Fixation of these fracture types can be accomplished using a variety of methods including the use of Kirschner wires, cannulated screws, and a combination of both materials. Stability of fracture fixation is of utmost importance as persistent motion at the fracture margin …
Integrating Biomechanics And Cell Physiology To Understanding Ivd Nutrition And Cell Homeostasis, Yongren Wu
Integrating Biomechanics And Cell Physiology To Understanding Ivd Nutrition And Cell Homeostasis, Yongren Wu
All Dissertations
Back pain associated with degeneration of the intervertebral disc (IVD) is a major public health problem in Western industrialized societies. Degeneration of the IVD changes the osmotic and nutrient environment in the extracellular matrix (ECM) which affects cell behaviors, including: cell proliferation, cell energy metabolism, and matrix synthesis. In addition, a thin layer of hyaline cartilaginous end-plate (CEP) at the superior/inferior disc-vertebral interface was found to play an important role in nutrient supply as well as load distribution in the IVD. Therefore, our general hypothesis is that the CEP regulates the ECM osmotic and nutrient environment which further affects IVD …