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Chemical Separation And Analyses Of Bioactive Compounds In Chloroform Fraction Of Oplopanax Horridus (Devil's Club), Lauren Wiseman
Chemical Separation And Analyses Of Bioactive Compounds In Chloroform Fraction Of Oplopanax Horridus (Devil's Club), Lauren Wiseman
All Theses
O. horridus (a member of the family Araliaceae) is a plant traditionally used by the tribe of Pacific Northwest America for medicinal as well as spiritual purposes. O. horridus is found in the temperate forests of northwestern North America as an understory shrub capable of growing in well-drained to poorly drained, shady sites. Traditional medical preparations of O. horridus include decoction or infusion, preparation as a tea, preparation as a poultice, or preparation as a tonic. O. horridus is used as a form of treatment for cancer, hypoglycemia, diabetes, tough pneumonia, and for colds. A practical and reliable extraction method …
Development And Application Of Scalable Two-Dimensional High Performance Liquid Chromatography For Aromatic Selective Separations Of Biologically Active Phytochemicals From Oplopanax Horridus, Gregory Jones
All Dissertations
The high demand for more efficient purification processes with increased automation and throughput pushes the development of more advanced preparative, pilot, and process scale HPLC instrumentation that is capable of achieving higher purities in a shorter amount of time than are currently achieved using one dimensional separations. A preparative scale 2D HPLC system was designed and reduced to practice in order to demonstrate the capacity for scalability of on-line comprehensive 2D HPLC separations of basic compounds from a challenging natural product extract of Oplopanax horridus. The methodology and instrumentation design herein permits direct method transfer from analytical to preparative scale …
Development Of Hplc Methods For The Determination Of Water-Soluble Vitamins In Pharmaceuticals And Fortified Food Products, Hung Khiem Trang
Development Of Hplc Methods For The Determination Of Water-Soluble Vitamins In Pharmaceuticals And Fortified Food Products, Hung Khiem Trang
All Theses
Though many HPLC methods have been developed and reported in literature for vitamin analysis for the past two decades, applying certain methods directly from literature more than often fails to reproduce the results reported due to many variables of liquid chromatography. This issue was targeted in this project through the examination of chromatographic behaviors of water-soluble vitamins in order to help the analysts better modify methods from literature or even develop new methods from scratch to fit their analytical need with the resources available (e.g., columns, detectors, etc.) in their lab.
The first part of the project investigated the chromatographic …
Biological Properties Evaluation And Chemical Profiles Of Phenolic Compounds In Muscadine Grapes (Vitis Rotundifolia), Qi You
All Dissertations
Phenolic compounds, including anthocyanins in muscadines have attracted much attention due to their diverse biological activities. With bioassays of antioxidant activities in terms of total phenolic content (TPC), total flavonoid content (TFC) total anthocyanin content (TAC), total procyanidin content (TPA), oxygen radical absorbance capacity (ORAC), ABTS radical scavenging Activity (ABTS), ferric reducing antioxidant power (FRAP), and oil peroxidation inhibitory capacity of all muscadine samples, the muscadine grapes showed strong antioxidant activities. The liquid-liquid organic solvent extraction successfully separated the anthocyanins and other phenolics to different fractions. Strong linear relationship between responses of TPC, TAC and TPA versus their antioxidant activities …
Sassafras Tea: Using A Traditional Method Of Preparation To Reduce The Carcinogenic Compound Safrole, Kate Cummings
Sassafras Tea: Using A Traditional Method Of Preparation To Reduce The Carcinogenic Compound Safrole, Kate Cummings
All Theses
The purpose of this research is to quantify the carcinogenic compound safrole in the traditional preparation method of making sassafras tea from the root of Sassafras albidum. The traditional method investigated was typical of preparation by members of the Eastern Band of Cherokee Indians and other Appalachian peoples. Sassafras is a tree common to the eastern coast of the United States, especially in the mountainous regions. Historically and continuing until today, roots of the tree are used to prepare fragrant teas and syrups. These traditional uses can be found across cultures throughout its range. Products made from sassafras are banned …