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Sex-Linked Mental Retardation Without Physical Stigmata (Martin-Bell Or Renpenning Type) : A Genetic And Psychometric Approach, Craig L. Hanis
Sex-Linked Mental Retardation Without Physical Stigmata (Martin-Bell Or Renpenning Type) : A Genetic And Psychometric Approach, Craig L. Hanis
Theses and Dissertations
Screening the Utah State Training School (a resident institution for the mentally retarded) for kindreds having at least two institutionalized sibs generated 54 sib groups. Of these, 20-male only sibships had histories compatible with sex-linked mental retardation without physical stigmata (Martin-Bell or Renpenning type). Affected males had no characteristic physical stigmata (an appreciable number did have speech problems and/or seizure disorders) and exhibited IQs ranging from 5 to 74 with a mean of 34.2. Obligate carrier females had a mean IQ score of 91.9 (range, 79 to 106), which is as would be predicted due to random X-inactivation. Carrier females …