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University of Central Florida

1975

Dirofilaria immitis

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Immunological Studies Of The Host Parasite Relationship Of Dirofilaria Immitis In Domestic Canines, Douglas Felton Qualls Jan 1975

Immunological Studies Of The Host Parasite Relationship Of Dirofilaria Immitis In Domestic Canines, Douglas Felton Qualls

Retrospective Theses and Dissertations

Canine immunoglobulins of the IgG group were shown to be intimately associated with the cuticle of circulating non-infection Dirofilaria immitis microfilaria. The significance of these immunoglobulins in blocking a complete immune response in the definitive host is discussed. Immunodiffusion, immunoelectrophoresis and fluorescent inhibition techniques are described and their applicability to the study of host-parasite relationships are evaluated. A rapid reproducible method for the production of specifically labeled anti-D. immitis microfilaria globulins is presented.