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A Sweet Way To Increase The Metabolic Activity And Migratory Response Of Wound-Related Cells: Deoxy-Sugar Incorporated Natural Polymeric Fibres As A Potential Bioactive Wound Patch, Serkan Di̇ki̇ci̇
Turkish Journal of Biology
The selection of a wound dressing is crucial for successful wound management. Conventional dressings are preferable for the treatment of simple wounds. However, a bioactive wound dressing that supports wound management and accelerates the healing process is required when it comes to treating non-self-healing wounds. 2-deoxy-D-ribose (2dDR) is a small deoxy sugar that naturally occurs in human body. Although we have previously demonstrated that 2dDR can be used to induce neovascularisation and accelerates wound healing in vitro and in vivo, the literature on small sugars is conflicting, and the knowledge on how 2dDR achieves its biological activity is very limited. …