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Brigham Young University

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Regulation Of Immune Cell Activation And Functionby The Nbmpp2 Protein Andthe Cd5 Co-Receptor, Claudia Mercedes Freitas Apr 2019

Regulation Of Immune Cell Activation And Functionby The Nbmpp2 Protein Andthe Cd5 Co-Receptor, Claudia Mercedes Freitas

Theses and Dissertations

According to the centers for disease control and prevention (CDC) and the world healthorganization (WHO), heart disease and immune related diseases such as diabetes and cancer areamong the leading causes of death around the world. Thus, the regulation of the function ofimmune cell plays a key role in health and disease. Calcium (Ca2+) ions play a critical role inimmune cell activation, function and in a robust immune response. Defects in Ca2+ signalinginfluences the development of cardiac disease, Alzheimer disease, immune cell metabolism,muscle dysfunction, and cancer. Each immune cell is unique in its activation and function,making it relevant to understand how …


Anti-Depressive And Anti-Obesity Changes Following Either Dietary Isoflavone Treatment Or Injection Treatment With The Isoflavonoid Equol: Positive Response Dependent On Animal Age And Ovarian Status In Female Long Evans Rats, Crystal Blake Jul 2010

Anti-Depressive And Anti-Obesity Changes Following Either Dietary Isoflavone Treatment Or Injection Treatment With The Isoflavonoid Equol: Positive Response Dependent On Animal Age And Ovarian Status In Female Long Evans Rats, Crystal Blake

Theses and Dissertations

Two conditions associated with ovarian depletion are increased potential for depressive episodes and increased abdominal weight gain. In five different experiments we examined the effect of soy-containing diets or equol injections on depression, serotonin levels, weight gain (BW) and white adipose tissue (WAT) deposition of female Long-Evans rats in various stages of life. Rats were intact, ovariectomized or experienced natural ovarian failure (NOF). While this paper will present each experiment, only experiment 5 is outlined here due to space limitations. From conception the rats were exposed to either a soy-rich (Phyto-600) or low-soy diet (Phyto-low). Animals experienced NOF at approximately …


The Effects Of A Resveratrol Derivative On Regulatory Behaviors And Reproductive Health In Male And Female Long-Evans Rats, Kimberly Michelle Fabick Mar 2008

The Effects Of A Resveratrol Derivative On Regulatory Behaviors And Reproductive Health In Male And Female Long-Evans Rats, Kimberly Michelle Fabick

Theses and Dissertations

Phytoestrogens are chemicals produced by plants that act like estrogens and have the ability to bind to the mammalian estrogen receptor system. The purpose of this study is to evaluate a new phytoestrogen analog called 4-acetoxy Resveratrol. Resveratrol is a phytoestrogen that has been found in the skin of grapes. Resveratrol has been shown to be able to bind to the estrogen receptors and has a similar molecular structure as estradiol. Resveratrol has been shown to have many positive health benefits such as improving cardiovascular health, serving as a neuroprotective agent, acting as an anti-inflammatory agent, working as an anti-cancer …


The Effects Of Prenatally Administered Phytoestrogens On The Reproductive And Behavioral Development Of Long-Evans Rats, Crystal Blake Mar 2008

The Effects Of Prenatally Administered Phytoestrogens On The Reproductive And Behavioral Development Of Long-Evans Rats, Crystal Blake

Theses and Dissertations

Equol is known to be a selective androgen modulator and has the ability to bind and inhibit 5-alpha dihydrotestosterone (5α-DHT). Equol is also a selective estrogen receptor modulator and is able to bind beta estrogen receptors with high affinity. As estrogen receptors are found in the hypothalamus, pituitary, and gonads, prenatally administered equol could affect the morphological and reproductive development of offspring. To test this hypothesis, during gestational days 14 to 20, forty-two pregnant Long-Evans rats were given one of six treatments: 1) no treatment, 2) injection with dimethyl sulfoxide (DMSO), 3) injection with 10 mg/kg equol, 4) injection with …


Behavior And Age Class Structure Of Wintering Northern Bald Eagles (Haliaeetus Leucocephalus Alascanus) In Western Utah, Ronald A. Joseph Jul 1977

Behavior And Age Class Structure Of Wintering Northern Bald Eagles (Haliaeetus Leucocephalus Alascanus) In Western Utah, Ronald A. Joseph

Theses and Dissertations

Bald Eagles in Cedar and Rush Valleys of western Utah were studied from 1975 to 1977. Arriving in mid-November, the eagles departed in mid-March. A statewide Bald Eagle census revealed 200 to 300 birds. Wintering eagle populations have remained stable for the past 10 years. Immatures comprised 35% of the population in 1975-76 and 33% in 1976-77. While Black-tailed jackrabbits are the primary food source of wintering eagles in western Utah, other mammalian carrion serve as supplementary food items. Eagles utilized 4 communal night roosts. Three day communal roosts were located on south facing slopes. The social existence of Bald …


Winter Behavior And Population Dynamics Of American Eagles In Western Utah, Clyde C. Edwards Aug 1969

Winter Behavior And Population Dynamics Of American Eagles In Western Utah, Clyde C. Edwards

Theses and Dissertations

The large size, extensive range, and irnporta.nt corrnnunity role of the Golden Eagle (Aguila chrysaetos L.) and the Bald Eagle (Haliae-etus leucocephalus L.) attract considerable scientific interest. Sorne aspects of their life history have been investigated and reported in detail, but their rapidly declining numbers (Sprunt and Ligas 1966, Cottam 1961) necessitate new investigations into all phases of their life history and particularly into population dynamics.