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The Effects Of Ketones On Brain Metabolism And Cognition, Erin Reiko Saito
The Effects Of Ketones On Brain Metabolism And Cognition, Erin Reiko Saito
Theses and Dissertations
The brain is one of the most energetically demanding organs within the human body and is cognitively susceptible to energetic deficits such that the rise in obesity, insulin resistance, and Alzheimer’s disease in recent decades pose a substantial threat to cognitive longevity. The therapeutic efficacy of ketones are well-established in epilepsy and are currently being applied to other disease states. Alzheimer’s disease is characterized by impairments in brain glucose uptake and metabolism in regions relevant to learning, memory, and cognition that progress with the disease. While brain glucose uptake is impaired, ketone uptake is unaltered, potentially enabling ketones to fuel …
Aiding Semantic Memory Creation With Navigational Context, Thomas Benjamin Lyle Wasden
Aiding Semantic Memory Creation With Navigational Context, Thomas Benjamin Lyle Wasden
Theses and Dissertations
While we have traditionally understood the hippocampus to be involved in memory and navigation, it also appears that it has a role in language processing, creation and prediction. An obvious explanation for this is that language is impossible if linguistic signs cannot be remembered and retrieved. Because linguistic signs are definitionally biologically neutral or arbitrary, we must use the brain's apparatus for learning and storing information from the external world to store and retrieve them. Although plausible, this explanation fails to take into account the hippocampus' role in navigation as a contributing element in the processing, storage and retrieval of …