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Sublingual Sufentanil Attenuates Perceived Pain, But Not Blood Pressure Responses, During A Cold Pressor Test, Caitlin P. Jarrard, Zachary J. Mckenna, Whitley C. Atkins, Josh Foster, Joseph C. Watso, Craig G. Crandall
Sublingual Sufentanil Attenuates Perceived Pain, But Not Blood Pressure Responses, During A Cold Pressor Test, Caitlin P. Jarrard, Zachary J. Mckenna, Whitley C. Atkins, Josh Foster, Joseph C. Watso, Craig G. Crandall
International Journal of Exercise Science: Conference Proceedings
Sublingual sufentanil was developed to reduce pain following a traumatic injury in the field (e.g., battlefield). However, it is unknown whether an analgesic dose of sufentanil affects cardiovascular responses to a painful stimulus in humans. PURPOSE: We tested the hypothesis that sublingual sufentanil blunts pain perception and the accompanying cardiovascular responses during a cold pressor test (CPT). METHODS: Twenty-nine adults, 15 males and 14 females (age: 29 ± 5 years, body mass: 74 ± 8 kg, body mass index: 25 ± 2 kg/m2) participated in this double-blind, randomized, crossover, placebo-controlled trial. Following sublingual administration of sufentanil (30 µg) …