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Analyses Of The 2020 Nobel Prize In Physiology Or Medicine: Taking The Hepatitis C Virus From Mystery Killer To Preventable And Treatable Disease, Neyda V. Gilman
Analyses Of The 2020 Nobel Prize In Physiology Or Medicine: Taking The Hepatitis C Virus From Mystery Killer To Preventable And Treatable Disease, Neyda V. Gilman
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Harvey J. Alter, Michael Houghton, and Charles M. Rice share the 2020 Nobel in Physiology or Medicine for their contributions to the identification, treatment, and eventual elimination of the hepatitis C virus (HCV). The then novel molecular techniques they used have laid the groundwork for future work on HCV and other viruses. This article will give a brief overview of the hepatitis disease and the work of this year's laureates. It will also take a bibliometric look at the scientist’s research and add to the discussions about the way modern science is done and the limitations of prestigious science awards …
Analyses Of The 2019 Nobel Prize In Physiology Or Medicine: Molecular Machinery For Cellular Oxygen Level Response, Neyda V. Gilman
Analyses Of The 2019 Nobel Prize In Physiology Or Medicine: Molecular Machinery For Cellular Oxygen Level Response, Neyda V. Gilman
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Gregg L. Semenza, William G Kaelin, Jr, and Sir Peter J. Ratcliffe were awarded the 2019 Nobel Prize for Physiology or Medicine on October 7, 2019. Their work led to the understanding of how cells recognize and adapt to varying oxygen levels. Hypoxia-inducible nuclear factors play an essential role in this mechanism by turning on other genes that work towards increasing oxygen levels in hypoxic environments. Other vital pieces of the machinery include von Hippel-Lindau proteins and prolyl hydroxylation. Due to the necessity of oxygen in numerous human physiological systems, this discovery will likely have nearly immeasurable impacts on human …
Natural Medicines, Neyda V. Gilman
Natural Medicines, Neyda V. Gilman
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Natural Medicines is a robust and authoritative resource for information related to complementary and alternative medicines, natural therapies, natural ingredients, and natural products. The content is evidence-based with the aim of being as objective and unbiased as possible, and monographs in the database include references for the information provided (Natural Medicines 2019a). It is a fee-based subscription product, but pricing is generally fair and it can be bundled with other resources of interest. There are some inconveniences, such as not working with discovery services or allowing Boolean or quotation searching, but overall the database is easy to use, reliable, and …
Analysis For Science Librarians Of The 2018 Nobel Prize In Physiology Or Medicine: The Life And Work Of James P. Allison And Tasuku Honjo, Neyda V. Gilman
Analysis For Science Librarians Of The 2018 Nobel Prize In Physiology Or Medicine: The Life And Work Of James P. Allison And Tasuku Honjo, Neyda V. Gilman
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On October 1, 2018, James P. Allison and Tasuku Honjo were awarded the 2018 Physiology or Medicine Nobel for their work leading to Immune Checkpoint Inhibition (ICI). ICI is the fourth pillar of cancer treatment and has been used to treat previously un-treatable cancers. Allison discovered that the protein CTLA-4 acts as a T cell brake while Honjo discovered another T cell brake, PD-1. Releasing these brakes allows the immune system to attack tumors, sometimes leading to complete elimination. While there is still more research to be done, Allison’s and Honjo’s work is a breakthrough in cancer immunotherapy.