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Genetics

Masters Theses & Specialist Projects

2010

Molecular virology

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The Genomic Sequence And Annotation Of Bacteriophage Hk239, Alice Ann Wright Dec 2010

The Genomic Sequence And Annotation Of Bacteriophage Hk239, Alice Ann Wright

Masters Theses & Specialist Projects

Bacteriophages are viruses that infect bacteria and they are the most numerous biological entities on Earth. Temperate phage can adopt two different lifestyles. In the lytic lifestyle, a phage injects its genome into the host and a controlled developmental program ensues. The phage DNA is replicated, phage genes are expressed and new viral particles are assembled. Ultimately, the host cell lyses and the phage particles are released into the environment. In the lysogenic lifestyle, a phage integrates its genome into the host chromosome, creating a prophage. The cell containing the prophage is known as a lysogen. Most prophage genes are …