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Changing Population Of Liver Transplant Recipients In The Era Of Direct-Acting Antiviral Therapy, Chencheng Xie, Yong-Fang Kuo, Ashwani K Singal
Changing Population Of Liver Transplant Recipients In The Era Of Direct-Acting Antiviral Therapy, Chencheng Xie, Yong-Fang Kuo, Ashwani K Singal
Division of Gastroenterology and Hepatology Faculty Papers
Background and Aims: With the availability of direct-acting antiviral (DAA) therapy for hepatitis C virus (HCV) infection and changing liver disease etiology for liver transplantation (LT), data on the changes in LT recipient population in the DAA era are scanty. Methods: The United Network for Organ Sharing (UNOS) registry (01/2007 to 06/2018) was used to develop a retrospective cohort of LT recipients for HCV, alco-hol-associated liver disease (ALD), and non-alcoholic steato-hepatitis (NASH). LT recipients in the DAA era (2013-2018) were compared with those in the pre-DAA era (2007-2012) era for recipient characteristics. Chi-square and analysis of variance were the statistical …