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Safety Of Endoscopic Retrograde Cholangiopancreatography (Ercp) In Pregnancy: A Systematic Review And Meta-Analysis, Mohamed Azab, Shishira Bharadwaj, Mahendran Jayaraj, Annie S. Hong, Pejman Solaimani, Mohamad Mubder, Hyeyoung Yeom, Ji Won Yoo, Michael L. Volk Dec 2019

Safety Of Endoscopic Retrograde Cholangiopancreatography (Ercp) In Pregnancy: A Systematic Review And Meta-Analysis, Mohamed Azab, Shishira Bharadwaj, Mahendran Jayaraj, Annie S. Hong, Pejman Solaimani, Mohamad Mubder, Hyeyoung Yeom, Ji Won Yoo, Michael L. Volk

School of Medicine Faculty Publications

Background/Aims: Endoscopic retrograde cholangiopancreatography (ERCP) is a technically challenging procedure rarely associated with severe postprocedure complications. Hormonal changes during pregnancy promote cholelithiasis, but there are limited clinical data available on the outcomes of ERCP in pregnant women. ERCP techniques without irradiation were recently introduced as potential alternative. We performed a systematic review and meta-analysis to assess the safety of ERCP in pregnancy and to compare outcomes of radiation versus nonradiation ERCP. Materials and Methods: A systematic search of PubMed, Medline/Ovid, Web of Science, and Google Scholar through April 18th, 2018 using PRISMA and MOOSE guidelines identified 27 studies reporting the …


Safety And Efficacy Of Combined Antegrade And Retrograde Endoscopic Dilation For Complete Esophageal Obstruction: A Systematic Review And Meta-Analysis, Mahendran Jayaraj, Babu P. Mohan, Harneet Mashiana, Rajesh Krishnamoorthi, Douglas G. Adler Jun 2019

Safety And Efficacy Of Combined Antegrade And Retrograde Endoscopic Dilation For Complete Esophageal Obstruction: A Systematic Review And Meta-Analysis, Mahendran Jayaraj, Babu P. Mohan, Harneet Mashiana, Rajesh Krishnamoorthi, Douglas G. Adler

School of Medicine Faculty Publications

Background Complete esophageal obstruction (CEO) due to occlusive proximal stricture occurs after chemoradiation for head and neck cancers. A combined antegrade and retrograde endoscopic technique with controlled recanalization and dilation (CARD) has been shown to be an effective and safe method for regaining and maintaining esophageal luminal patency in the short term. Methods We conducted a comprehensive search of multiple electronic databases and conference proceedings, including PubMed, EMBASE, and Web of Science databases (from inception through November 2018), to identify studies that reported the outcomes of CARD. The primary outcomes were the pooled rates of technical and clinical success, specifically …


Hot Snare Vs. Cold Snare Polypectomy For Endoscopic Removal Of 4-10mm Colorectal Polyps During Colonoscopy: A Systematic Review And Meta-Analysis Of Randomized Controlled Studies, Mahendran Jayaraj May 2019

Hot Snare Vs. Cold Snare Polypectomy For Endoscopic Removal Of 4-10mm Colorectal Polyps During Colonoscopy: A Systematic Review And Meta-Analysis Of Randomized Controlled Studies, Mahendran Jayaraj

School of Medicine Faculty Publications

Introduction In recent years, cold snare polypectomy (CSP) has increasingly been used over hot snare polypectomy (HSP) for the removal of colorectal polyps (4 – 10 mm in size). However, the optimal technique (CSP vs. HSP), in terms of complete polyp resection and complications, is uncertain. Our aim was to compare incomplete resection rate (IRR) of polyps and complications using CSP vs. HSP. Methods Randomized controlled studies (RCTs) comparing CSP and HSP for removal of 4 – 10 mm colorectal polyps were considered. Studies were included in the analysis if they obtained biopsy specimens from the resection margin to confirm …