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Forensic Science and Technology

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City University of New York (CUNY)

Optimization

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Method Optimization For The Determination Of Cannabinoids In Blood By Liquid Chromatography Tandem Mass Spectrometry (Lc-Ms/Ms), Kevin D. Carrera Aug 2022

Method Optimization For The Determination Of Cannabinoids In Blood By Liquid Chromatography Tandem Mass Spectrometry (Lc-Ms/Ms), Kevin D. Carrera

Student Theses

Delta-9-tetrahydrocannabinol (THC) continues to be one of the most popular drugs in the USA. Along with THC, other cannabinoids such as cannabidiol (CBD), are on the rise due to an increase in medicinal usage as well as the passage of different legislations removing these products from their current schedule I status. Thus, an urgency exists to develop robust and sensitive analytical methods to determine cannabinoids, especially THC, CBD and metabolites, in biological samples. The purpose of this study was to investigate different analytical procedures to determine the best method to identify and quantify CBD, THC and their metabolites in whole …