Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Conditioned avoidance response (4)
- Sensitization (4)
- Tolerance (3)
- Clozapine (2)
- Maternal behavior (2)
-
- Objectification (2)
- Olanzapine (2)
- Pavlovian conditioning (2)
- Phencyclidine (2)
- 5-HT2A (1)
- 5-HT2C (1)
- 5-hydroxytryptamine 2A receptor (1)
- 5-hydroxytryptamine 2C receptor (1)
- Adolescence (1)
- Alcohol intoxication (1)
- Anger-superiority (1)
- Appetitive stimuli (1)
- Aripiprazole (1)
- Attention (1)
- Body image (1)
- Body recognition (1)
- C-Fos (1)
- CS1 and CS2 (1)
- Citalopram (1)
- Cognitive processes (1)
- Competence (1)
- Depression (1)
- Drug discrimination (1)
- Drug–drug conditioning (1)
- Eye fixation (1)
Articles 1 - 13 of 13
Full-Text Articles in Entire DC Network
Serotonin 5-Ht2a And 5-Ht2c Receptors Regulate Rat Maternal Behavior Through Distinct Behavioral And Neural Mechanisms, Jun Gao, Lina Nie, Yu Li, Ming Li
Serotonin 5-Ht2a And 5-Ht2c Receptors Regulate Rat Maternal Behavior Through Distinct Behavioral And Neural Mechanisms, Jun Gao, Lina Nie, Yu Li, Ming Li
Department of Psychology: Faculty Publications
Serotonin 5-HT2A and 5-HT2C receptors play important yet distinctive roles in the regulation of rat maternal behavior. The present study investigated their neural substrates and explored the possible behavioral mechanisms (i.e., behavioral organization or maternal motivation). Sprague-Dawley postpartum females were microinjected with either a selective 5-HT2A agonist (TCB-2, 0.4 or 4.0 μg/side) or a 5-HT2C agonist (MK212, 2.5 or 5.0 μg/side) into the medial prefrontal cortex (mPFC) or ventral tegmental area (VTA). Ten and 60 min later, their maternal activities were observed in the home cage; and their motivational responses towards pups were examined in a …
Beauty Is In The Eye Of The Beer Holder: An Initial Investigation Of The Effects Of Alcohol, Attractiveness, Warmth, And Competence On The Objectifying Gaze In Men, Abigail R. Riemer, Michelle Haikalis, Molly R. Franz, Michael Dodd, David Dilillo, Sarah Gervais
Beauty Is In The Eye Of The Beer Holder: An Initial Investigation Of The Effects Of Alcohol, Attractiveness, Warmth, And Competence On The Objectifying Gaze In Men, Abigail R. Riemer, Michelle Haikalis, Molly R. Franz, Michael Dodd, David Dilillo, Sarah Gervais
Department of Psychology: Faculty Publications
Despite literature revealing the adverse consequences of objectifying gazes for women, little work has empirically examined origins of objectifying gazes by perceivers. Integrating alcohol myopia and objectification theories, we examined the effects of alcohol as well as perceived female attractiveness, warmth, and competence on objectifying gazes. Specifically, male undergraduates (n = 49) from a large U.S. Midwestern university were administered either an alcoholic or placebo beverage. After consumption, participants were asked to focus on the appearance or personality (counterbalanced) of pictured women who were previously rated as high, average, or low in attractiveness, warmth, and competence. Replicating previous work, appearance …
Effects Of Repeated Quetiapine Treatment On Conditioned Avoidance Responding In Rats, Jun Gao, Min Feng, Natashia Swalve, Collin Davis, Nan Sui, Ming Li
Effects Of Repeated Quetiapine Treatment On Conditioned Avoidance Responding In Rats, Jun Gao, Min Feng, Natashia Swalve, Collin Davis, Nan Sui, Ming Li
Department of Psychology: Faculty Publications
The present study characterized the behavioral mechanisms of avoidance–disruptive effect of quetiapine in the conditioned avoidance response test under two behavioral testing (2 warning signals vs. 1 warning signal) and two drug administration conditions (subcutaneous vs. intravenous). In Experiments 1 and 2, well-trained adult male Sprague-Dawley rats were tested under the subcutaneous (s.c.) quetiapine treatment (5.0, 15.0, 25.0, 50.0 mg/kg) for 7 days in a novel procedure consisting of two conditioned stimuli (CS) (white noise serving as CS1 and pure tone as CS2). Only the highest dose (50.0 mg/kg) produced a persistent suppression of the avoidance response without impairing the …
From Sex Objects To Human Beings: Masking Sexual Body Parts And Humanization As Moderators To Women’S Objectification, Philippe Bernard, Sarah Gervais, Jill Allen, Alice Delmée, Olivier Klein
From Sex Objects To Human Beings: Masking Sexual Body Parts And Humanization As Moderators To Women’S Objectification, Philippe Bernard, Sarah Gervais, Jill Allen, Alice Delmée, Olivier Klein
Department of Psychology: Faculty Publications
Recent studies have shown that sexualized female bodies are objectified at a cognitive level. Research using the body-inversion recognition task, a robust indicator of configural (vs. analytic processing) within cognitive psychology, shows that for sexualized female bodies, people recognize upright and inverted bodies similarly rather than recognizing upright bodies better than inverted bodies (i.e., an inversion effect). This finding suggests that sexualized female bodies, like objects, are recognized analytically (rather than configurally). Nonetheless, it remains unclear when and why sexualized female bodies are objectified at a basic cognitive level. Grounded in objectification theory, the present experiments examine moderating factors that …
Repeated Administration Of Aripiprazole Produces A Sensitization Effect In The Suppression Of Avoidance Responding And Phencyclidine-Induced Hyperlocomotion And Increases D2 Receptor-Mediated Behavioral Function, Jun Gao, Rongyin Qin, Ming Li
Repeated Administration Of Aripiprazole Produces A Sensitization Effect In The Suppression Of Avoidance Responding And Phencyclidine-Induced Hyperlocomotion And Increases D2 Receptor-Mediated Behavioral Function, Jun Gao, Rongyin Qin, Ming Li
Department of Psychology: Faculty Publications
The present study investigated how repeated administration of aripiprazole (a novel antipsychotic drug) alters its behavioral effects in two behavioral tests of antipsychotic activity and whether this alteration is correlated with an increase in dopamine D2 receptor function. Male adult Sprague-Dawley rats were first repeatedly tested with aripiprazole (3, 10 and 30 mg/kg, subcutaneously (sc)) or vehicle in a conditioned avoidance response (CAR) test or a phencyclidine (PCP) (3.20 mg/kg, sc)-induced hyperlocomotion test daily for five consecutive days. After 2–3 days of drug-free retraining or resting, all rats were then challenged with aripiprazole (1.5 or 3.0 mg/kg, sc). Repeated …
Repeated Effects Of The Neurotensin Receptor Agonist Pd149163 In Three Animal Tests Of Antipsychotic Activity: Assessing For Tolerance And Cross-Tolerance To Clozapine, Shinnyi Chou, Collin Davis, Sean Jones, Ming Li
Repeated Effects Of The Neurotensin Receptor Agonist Pd149163 In Three Animal Tests Of Antipsychotic Activity: Assessing For Tolerance And Cross-Tolerance To Clozapine, Shinnyi Chou, Collin Davis, Sean Jones, Ming Li
Department of Psychology: Faculty Publications
Neurotensin is an endogenous neuropeptide closely associated with the mesolimbic dopaminergic system and shown to possess antipsychotic-like effects. In particular, acute neurotensin receptor activation can inhibit conditioned avoidance response (CAR), attenuate phencyclidine (PCP)-induced prepulse inhibition (PPI) disruptions, and reverse PCP-induced hyperlocomotion. However, few studies have examined the long term effects of repeated neurotensin receptor activation and results are inconsistent. Since clinical administration of antipsychotic therapy often requires a prolonged treatment schedule, here we assessed the effects of repeated activation of neurotensin receptors using an NTS1 receptor selective agonist, PD149163, in 3 behavioral tests of antipsychotic activity. We also investigated whether …
The Effects Of Social Anxiety And State Anxiety On Visual Attention: Testing The Vigilance–Avoidance Hypothesis, J. Suzanne Singh, Michelle C. Capozzoli, Michael Dodd, Debra Hope
The Effects Of Social Anxiety And State Anxiety On Visual Attention: Testing The Vigilance–Avoidance Hypothesis, J. Suzanne Singh, Michelle C. Capozzoli, Michael Dodd, Debra Hope
Department of Psychology: Faculty Publications
A growing theoretical and research literature suggests that trait and state social anxiety can predict attentional patterns in the presence of emotional stimuli. The current study adds to this literature by examining the effects of state anxiety on visual attention and testing the vigilance– avoidance hypothesis, using a method of continuous visual attentional assessment. Participants were 91 undergraduate college students with high or low trait fear of negative evaluation (FNE), a core aspect of social anxiety, who were randomly assigned to either a high or low state anxiety condition. Participants engaged in a free view task in which pairs of …
Effects Of 5-Hydroxytryptamine 2c Receptor Agonist Mk212 And 2a Receptor Antagonist Mdl100907 On Maternal Behavior In Postpartum Female Rats, Weihai Chen, Qi Zhang, Wenxin Su, Yu Yang, Jing Qiao, Nan Sui, Ming Li
Effects Of 5-Hydroxytryptamine 2c Receptor Agonist Mk212 And 2a Receptor Antagonist Mdl100907 On Maternal Behavior In Postpartum Female Rats, Weihai Chen, Qi Zhang, Wenxin Su, Yu Yang, Jing Qiao, Nan Sui, Ming Li
Department of Psychology: Faculty Publications
Maternal behavior in rats is a highly motivated and well-organized social behavior. Given the known roles of serotonin (5-HT) in emotion, motivation, social behavior, and major depression – and its known interaction with dopamine – it is likely that serotonin also plays a crucial role in this behavior. So far, there are surprisingly few studies focusing on 5-HT in maternal behavior, except for maternal aggression. In the present study,we examined the effects of 5-HT2C receptor agonism and 5-HT2A receptor antagonism on maternal behavior in postpartum female rats.We hypothesized that activation of 5-HT2C receptors and blockade of 5-HT …
The Politics Of The Face-In-The-Crowd, Mark S. Mills, Kevin B. Smith, John R. Hibbing, Michael Dodd
The Politics Of The Face-In-The-Crowd, Mark S. Mills, Kevin B. Smith, John R. Hibbing, Michael Dodd
Department of Psychology: Faculty Publications
Recent work indicates that the more conservative one is, the faster one is to fixate on negative stimuli, whereas the less conservative one is, the faster one is to fixate on positive stimuli. The present series of experiments used the face-in-the-crowd paradigm to examine whether variability in the efficiency with which positive and negative stimuli are detected underlies such speed differences. Participants searched for a discrepant facial expression (happy or angry) amid a varying number of neutral distractors (Experiments 1 and 4). A combination of response time and eye movement analyses indicated that variability in search efficiency explained speed differences …
Long-Term Impacts Of Adolescent Risperidone Treatment On Behavioral Responsiveness To Olanzapine And Clozapine In Adulthood, Jing Qiao, Qinglin Zhang, Ming Li
Long-Term Impacts Of Adolescent Risperidone Treatment On Behavioral Responsiveness To Olanzapine And Clozapine In Adulthood, Jing Qiao, Qinglin Zhang, Ming Li
Department of Psychology: Faculty Publications
This preclinical study investigated howa short-termrisperidone treatment in adolescence impacts antipsychotic response to olanzapine and clozapine in adulthood. Antipsychotic effect was indexed by a drug's suppressive effect on avoidance responding in a rat conditioned avoidance response (CAR) model. Male adolescent Sprague–Dawley rats were first treated with risperidone (1.0mg/kg, sc) or sterile water and tested in the CAR model for 5 consecutive days from postnatal days P 40 to 44. After they became adults (~P 80–84), they were switched to olanzapine (0.5mg/kg, sc), clozapine (5.0mg/kg, sc) or vehicle treatment and tested for avoidance for 5 days. During the adolescent period, repeated …
Which Way Is Which? Examining Global/Local Processing With Symbolic Cues, Mark Mills, Michael Dodd
Which Way Is Which? Examining Global/Local Processing With Symbolic Cues, Mark Mills, Michael Dodd
Department of Psychology: Faculty Publications
A new method combining spatial-cueing and compound-stimulus paradigms draws on involuntary attentional orienting elicited by a spatially uninformative central arrow cue to investigate global/local processing under incidental processing conditions, wherein global/local levels were uninformative (do not aid performance) and task-irrelevant (need not be processed to perform the task). The task was peripheral target detection. Cues were compound arrows, which were either consistent (global/local arrows oriented in same direction) or inconsistent (global/local arrows oriented in opposite directions). Global/local processing was measured by spatial-cueing effects (response time [RT] difference between target locations validly cued by an arrow and targets at different locations), …
Drug–Drug Conditioning Between Citalopram And Haloperidol Or Olanzapine In A Conditioned Avoidance Response Model: Implications For Polypharmacy In Schizophrenia, Nathan L. Sparkman, Ming Li
Drug–Drug Conditioning Between Citalopram And Haloperidol Or Olanzapine In A Conditioned Avoidance Response Model: Implications For Polypharmacy In Schizophrenia, Nathan L. Sparkman, Ming Li
Department of Psychology: Faculty Publications
Patients with schizophrenia often have anxiety and depression, and thus are treated with multiple psychotherapeutic medications. This practice of polypharmacy increases the possibility for drug–drug interactions. However, the pharmacological and behavioral mechanisms underlying drug–drug interactions in schizophrenia remain poorly understood. In the present study, we adopted a preclinical approach and examined a less known behavioral mechanism, drug–drug conditioning (DDC) between haloperidol (a typical antipsychotic) or olanzapine (atypical antipsychotic) and citalopram (a selective serotonin reuptake inhibitor). A rat two-way conditioned avoidance response paradigm was used to measure antipsychotic activity and determine how DDC may alter the antipsychotic efficacy in this model. …
Conditioned Response Evoked By Nicotine Conditioned Stimulus Preferentially Induces C-Fos Expression In Medial Regions Of Caudate-Putamen, Sergios Charntikov, Matthew E. Tracy, Changjiu Zhao, Ming Li, Rick A. Bevins
Conditioned Response Evoked By Nicotine Conditioned Stimulus Preferentially Induces C-Fos Expression In Medial Regions Of Caudate-Putamen, Sergios Charntikov, Matthew E. Tracy, Changjiu Zhao, Ming Li, Rick A. Bevins
Department of Psychology: Faculty Publications
Nicotine has both unconditioned and conditioned stimulus properties. Conditioned stimulus properties of nicotine may contribute to the tenacity of nicotine addiction. The purpose of this experiment was to use neurohistochemical analysis of rapidly developing c-Fos protein to elucidate neurobiological loci involved in the processing of nicotine as an interoceptive conditioned stimulus (CS). Rats were injected (SC) in an intermixed fashion with saline or nicotine (16 sessions of each) and placed in conditioning chambers where they were given one of the three conditions depending on group assignment: (a) nicotine paired 100% of the time with intermittent access to sucrose (nicotine-CS condition), …