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Maternal Immune Activation (Mia) In Mice: A Study To Phenotype Asd-Related Communication Behaviors And Analyze Maternal Health Outcomes In The Us, Komalpreet Gulati Dec 2018

Maternal Immune Activation (Mia) In Mice: A Study To Phenotype Asd-Related Communication Behaviors And Analyze Maternal Health Outcomes In The Us, Komalpreet Gulati

Honors Scholar Theses

Core symptoms of Autism Spectrum Disorders (ASD) include deficits in social/communicative behaviors, and repetitive/stereotyped behaviors. Mouse models are a highly established paradigm used to study the phenotypic deficits that result from various inducible genotypic or environmental risk factors for ASD. Previous studies have demonstrated a link between maternal immune activation (MIA) and ASD-like behaviors in mouse models. In this model, the maternal immune system is activated during pregnancy by injecting the viral mimic poly(I:C). The resulting offspring are phenotyped and analyzed with regards to their communicative behaviors.

Previous studies have demonstrated that male pups born to dams with immune activation …


It's About Communities: The Commitment To Promoting A Culturally Competent Environmental Health Workforce, Clint Pinion Jr., Leslie D. Mitchell, Jason W. Marion Sep 2018

It's About Communities: The Commitment To Promoting A Culturally Competent Environmental Health Workforce, Clint Pinion Jr., Leslie D. Mitchell, Jason W. Marion

EKU Faculty and Staff Scholarship

Environmental health and public health are profoundly local. The Association of Environmental Health Academic Programs (AEHAP) firmly agrees and for this reason, it is important to have local environmental health experts who know the pulse of their communities. AEHAP believes in supporting the advanced scientific education of environmental health in these communities through people from these communities. Accordingly, AEHAP has sought to promote and support accredited environmental health programs among a diverse cross-section of the U.S. higher education landscape. AEHAP’s students are diverse in many ways, including socioeconomically, racially, ethnically, and culturally. The value of this approach enhances the overall …


Indoor Air Quality In Schools, Clint Pinion Jr. Jan 2018

Indoor Air Quality In Schools, Clint Pinion Jr.

EKU Faculty and Staff Scholarship

An indoor air quality study was conducted on a ‘net-zero energy’ school using a TSI Velocicalc Model 9555-p with probe model 982, passive radon monitors, visual inspection protocol, and an indoor environmental quality survey of school faculty and staff. Average indoor temperature, relative humidity, and carbon dioxide levels in several areas within the school were not within IAQ guidelines. Three rooms on the school’s grounds had radon levels exceeding the action level. Recommended solutions included installing return and supply air ducts in hallways and relative humidity and temperature monitors in classrooms with high-pitched ceilings.


Improving Public Health Readiness For Sea Level Rise: A New Initiative In Coastal Virginia, Steven M. Becker Jan 2018

Improving Public Health Readiness For Sea Level Rise: A New Initiative In Coastal Virginia, Steven M. Becker

Community & Environmental Health Faculty Publications

Sea level has been rising around the world, and in recent decades, the rate has been accelerating. Because rising seas have the potential to directly or indirectly affect the health of vast numbers of coastal communities and inhabitants, public health agencies and professionals—in conjunction with other fields—have a pivotal role to play in helping to protect populations, reduce and prevent health impacts, and foster resilience. This article discusses a novel effort that has been undertaken in Coastal Virginia to help prepare the next generation of public health professionals to grapple with sea level rise issues. The effort grew out of …