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Omics As Therapeutic Platform: Environmental Factors To Parkinson's Disease, Hong-Duck Kim, Shana Warner, Kamini Singh, Jae-Hyeon Cho, Diane E. Heck
Omics As Therapeutic Platform: Environmental Factors To Parkinson's Disease, Hong-Duck Kim, Shana Warner, Kamini Singh, Jae-Hyeon Cho, Diane E. Heck
NYMC Faculty Publications
No abstract provided.
Rubus Crataegifolius Bunge Regulates Adipogenesis Through Akt And Inhibits High-Fat Diet-Induced Obesity In Rats, Min-Sup Jung, Soo-Jung Lee, Yuno Song, Sun-Hee Jang, Wongi Min, Chung-Kil Won, Hong-Duck Kim, Tae Hoon Kim, Jae-Hyeon Cho
Rubus Crataegifolius Bunge Regulates Adipogenesis Through Akt And Inhibits High-Fat Diet-Induced Obesity In Rats, Min-Sup Jung, Soo-Jung Lee, Yuno Song, Sun-Hee Jang, Wongi Min, Chung-Kil Won, Hong-Duck Kim, Tae Hoon Kim, Jae-Hyeon Cho
NYMC Faculty Publications
BACKGROUND: Obesity is one of the greatest public health problems and major risk factors for serious metabolic diseases and significantly increases the risk of premature death. The aim of this study was to determine the inhibitory effects of Rubus crataegifolius Bunge (RCB) on adipocyte differentiation in 3 T3-L1 cells and its anti-obesity properties in high fat diet (HFD)-induced obese rats.
METHODS: 3 T3-L1 adipocytes and HFD-induced obese rats were treated with RCB, and its effect on gene expression was analyzed using RT-PCR and Western blotting experiments.
RESULTS: RCB treatment significantly inhibited adipocyte differentiation by suppressing the expression of C/EBPβ, C/EBPα, …