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Development Of An Lcms Analytical Method With Applicability To Determination Of Trace Level Explosives In Environmental Waters, Cristina I. Veresmortean
Development Of An Lcms Analytical Method With Applicability To Determination Of Trace Level Explosives In Environmental Waters, Cristina I. Veresmortean
Dissertations, Theses, and Capstone Projects
Traces of explosives and their degradation products present in explosives contaminated sites from military sources, such as training facilities, impose a great concern over the public health and our eco-system. This work is centered around finding an efficient way to extraction of these chemicals from water samples and their analysis using advanced separation technology: LC-MS/MS Shimadzu Prominence 8050 and AB Sciex Trap 4000 LC-MS/MS. Different extraction methods will be proposed, along with chromatographic and mass spectroscopy method development. Dependent on the target analyte polarity, thermal degradation, solubility and type of matrix, an appropriate method of analysis will be established. The …