Digital Commons Network^™

Multiparametric Quantitative Acoustic Imaging Of Cervical Remodeling During Pregnancy, Yan Yan

Wayne State University Dissertations

The uterine cervix plays a central role in the maintenance of pregnancy and the process of parturition. Untimely cervical ripening in early gestation predisposes to preterm labor and delivery, the leading cause of infant mortality worldwide. The current approach to evaluate the status of the cervix relies on digital and sonographic examination, which indicates the morphological changes of the cervix (cervical length). Therefore, assessing cervix tissue composition changes may provide more sensitive evaluations about cervix status beyond cervical length. Photoacoustic (PA) imaging is a relatively new, non-invasive ultrasound (US) based technology that captures acoustic signals emitted by tissue components in …

Assessing Midbrain Abnormalities In Parkinson’S Disease Using Magnetic Resonance Imaging, Kiarash Ghassaban

Wayne State University Dissertations

Diagnosing early-stage Parkinson’s disease (PD) and its manifestations is still a clinical challenge. Previous imaging studies using iron, neuromelanin (NM) and the Nigrosome-1 (N1) measures in the substantia nigra (SN) by themselves have been unable to provide sufficiently high diagnostic performance for these methods to be adopted clinically. In this dissertation, we start by studying idiopathic PD patients at their intermediate stages of the disease to evaluate the role of global and regional iron in the major deep gray matter nuclei. Then, we only focus on the NM complex in the midbrain and how neuronal loss interact with iron overload …

Medical Surge Capability: Performance Modeling Of Hospital Emergency Departments, Egbe-Etu Emmanuel Etu

Wayne State University Dissertations

Hospitals are faced with significant challenges during and after natural or human-caused disasters. Surge planning is a critical component of every healthcare facility’s emergency plan and response system. The process of managing and allocating scarce resources by tackling the vulnerability inherent to patients means that defining improvement priorities is one of the main challenges healthcare systems face when responding to a medical surge event (e.g., COVID-19). The consequences of these challenges include increased patient mortality, ambulance diversion, long wait times, and unavailability of beds. Previous efforts in hospital operations management have successfully applied operations research techniques in analyzing and optimizing …

Maximizing User Engagement In Short Marketing Campaigns Within An Online Living Lab: A Reinforcement Learning Perspective, Aniekan Michael Ini-Abasi

Wayne State University Dissertations

ABSTRACT

MAXIMIZING USER ENGAGEMENT IN SHORT MARKETING CAMPAIGNS WITHIN AN ONLINE LIVING LAB: A REINFORCEMENT LEARNING PERSPECTIVE

by

ANIEKAN MICHAEL INI-ABASI

August 2021

Advisor: Dr. Ratna Babu Chinnam Major: Industrial & Systems Engineering Degree: Doctor of Philosophy

User engagement has emerged as the engine driving online business growth. Many firms have pay incentives tied to engagement and growth metrics. These corporations are turning to recommender systems as the tool of choice in the business of maximizing engagement. LinkedIn reported a 40% higher email response with the introduction of a new recommender system. At Amazon 35% of sales originate from recommendations, …

Integrated Optimization And Learning Methods Of Predictive And Prescriptive Analytics, Mehmet Kolcu

Wayne State University Dissertations

A typical decision problem optimizes one or more objectives subject to a set of constraints on its decision variables. Most real-world decision problems contain uncertain parameters. The exponential growth of data availability, ease of accessibility in computational power, and more efficient optimization techniques have paved the way for machine learning tools to effectively predict these uncertain parameters. Traditional machine learning models measure the quality of predictions based on the closeness between true and predicted values and ignore decision problems involving uncertain parameters for which predicted values are treated as the true values.Standard approaches passing point estimates of machine learning models …

High Mobility N-Type Field Effect Transistors Enabled By Wse2/Pdse2 Heterojunctions, Arthur Bowman Iii

Wayne State University Dissertations

Two-dimensional (2D) semiconductors such as transition metal dichalcogenides (TMDs) have emerged as a promising candidate for post-silicon electronics. Few-layer tungsten diselenide (WSe2), a well-studied TMD, has sown high hole mobility and ON/OFF ratio in field effect transistor (FET) devices. But the n-type performance of WSe2 is still quite limited by the presence of a substantial Schottky Barrier. Palladium diselenide, (PdSe2) is a newly discovered TMD that is of interest because of its high electron mobility, and moderate ON/OFF ratios. However, despite its relatively small bandgap, the n-type performance of few-layer PdSe2 FETs has also been limited by a Schottky barrier, …

The Advanced Applications For Optical Coherence Tomography In Skin Imaging, Qiuyun Xu

Wayne State University Dissertations

Optical coherence tomography (OCT), based on the principle of interferometry, is a fast and non-invasive imaging modality, which has been approved by FDA for dermatologic applications. OCT has high spatial resolution up to micrometer scale compared to traditional ultrasound imaging. In addition, OCT can provide real-time cross-sectional images with 1 to 2 mm penetration depth, which makes it an ideal imaging technique to assess the skin micro-morphology and pathology without any tissue removal. Many studies have investigated the possibilities of using OCT to evaluate dermatologic conditions, such as skin cancer, dermatitis, psoriasis, and skin damages. Hence, OCT has tremendous potential …

Framework For Effective Resilience Managmenet Of Complex Supply Networks, Elham Taghizadeh

Wayne State University Dissertations

In today's environment with high global and complex supply chains for engineered products, the ability to assess and manage the resilience of supply chains is not a luxury but a fundamental prerequisite for business continuity and success. This is particularly true for firms with deep-tier supply chains, such as the automotive original equipment manufacturers (OEMs) and their suppliers. Automotive supply networks are particularly facing growing challenges due to their complexity, globalization, economic volatility, rapidly changing technologies, regulations, and environmental/political shocks. These risks and challenges can disrupt and halt operations in any section of the supply network. Given that supply chains …

Intelligent Healthcare Process Discovery And Operational Coordination Using Discrete Event Simulation And Machine Learning, Suleyman Yildirim

Wayne State University Dissertations

The healthcare system in the US is rapidly changing and reshaping to adopt continuously evolving demand for improved operational efficiency and treatment effectiveness from patients and providers in critical health services. Healthcare service systems and clinical treatment operations need to be more predictable to increase operational efficiency through proactive operations management. This research contributes to the literature by discovering clinical processes and calibrating discrete-event simulation models in healthcare service systems using data-driven and process-driven predictive models. Unlike the data-driven predictive approaches such as machine learning and statistical methods, the proposed methodologies in this thesis leverages and focuses on process-based methods …

Software As A Service: The Mediating Role Of Consequences Of Saas Diffusion On Firm Performance, Cristina Marie-Mccarthy Recchia

Wayne State University Dissertations

ABSTRACTSOFTWARE AS A SERVICE: THE MEDIATING ROLE OF CONSEQUENCES OF SAAS DIFFUSION ON FIRM PERFORMANCE by CRISTINA MARIE-MCCARTHY RECCHIA DECEMBER 2021 Advisor: Dr. Ratna Babu Chinnam Major: Industrial Engineering Degree: Doctor of Philosophy There are ample studies that support a positive link between information technology and firm performance. Bharadwaj (2000) and Chae (2014, 2018) are two examples that provided a foundation for this work. These scholars looked at how capabilities associated with information technology contribute to improved financial performance using a specific set of financial ratios. In addition, there are studies that examine a positive link between Software-as-a-Service (SaaS) and …

Secure Automatic Speaker Verification Systems, Muteb Aljasem

Wayne State University Dissertations

The growing number of voice-enabled devices and applications consider automatic speaker verification (ASV) a fundamental component. However, maximum outreach for ASV in critical domains e.g., financial services and health care, is not possible unless we overcome security breaches caused by voice cloning, and replayed audios collectively known as the spoofing attacks. The audio spoofing attacks over ASV systems on one hand strictly limit the usability of voice-enabled applications; and on the other hand, the counterfeiter also remains untraceable. Therefore, to overcome these vulnerabilities, a secure ASV (SASV) system is presented in this dissertation. The proposed SASV system is based on …