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Centrifugal Automation Of A Triglyceride Bioassay On A Low-Cost Hybrid Paper-Polymer Device, Neus Godino, Elizaveta Vereshchagina, Robert Gorkin Iii, Jens Ducree

Robert Gorkin III

We present a novel paper-polymer hybrid construct for the simple automation of fundamental microfluidic operations in a lab-on-a-disc platform. The novel design, we term a paper siphon, consists of chromatographic paper strips embedded along a siphon microchannel. The paper siphon relies on two main interplaying forces to create unique valving and liquid-sampling methods in centrifugal microfluidics. At sufficiently low speeds, the inherent wicking of the paper overcomes the rotationally induced centrifugal force to drive liquids towards inwards positions of the disc. At elevated speeds, the dominant centrifugal force will extract liquid from the siphon paper strip towards the edge of …