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Acoustic Radiation Force And Its Application For Cell Manipulation And Ion Channels Activation, Xiangjun Peng
Acoustic Radiation Force And Its Application For Cell Manipulation And Ion Channels Activation, Xiangjun Peng
McKelvey School of Engineering Theses & Dissertations
Sound is a stress wave that carries energy and momentum flux. Scattered sound waves can generate acoustic radiation force that can be used to manipulate particles or cells. This dissertation demonstrates the physics behind cell manipulation by ultrasound. The work begins with a detailed analysis of the mechanics of using standing surface acoustic waves to fabricate acoustic tweezers for contactless particle manipulation using acoustic radiation force. Models to design and analyze acoustic radiation force have traditionally relied on plane wave theories that cannot predict how standing surface acoustic waves can levitate cells in the direction perpendicular to the substrate. We …
Effects Of Tendon Viscoelasticity On The Distribution Of Forces Across Sutures In A Model Tendon-To-Bone Repair, Yuxuan Huang
Effects Of Tendon Viscoelasticity On The Distribution Of Forces Across Sutures In A Model Tendon-To-Bone Repair, Yuxuan Huang
McKelvey School of Engineering Theses & Dissertations
Tears to the rotator cuff often require surgical repair. These repairs often culminate in re-tearing when sutures break through the tendon in the weeks following repair. Numerous studies have been performed to identify suturing strategies that reduce this risk by balancing forces across sutures. However, the structural engineering basis for these approaches is still emerging, and the effects of tendon mechanics on load balancing is still unclear. Specifically, the effects of the viscoelastic nature of tendon on load sharing have not been established. With the aim of providing insight into this problem, this thesis studies how tendon viscoelasticity, tendon stiffness, …