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The Brain's Large-Scale Electrophysiological Signals : Fundamental Attributes And Neurosurgical Applications, Mohammad Amin N/A Nourmohammadi Jan 2020

The Brain's Large-Scale Electrophysiological Signals : Fundamental Attributes And Neurosurgical Applications, Mohammad Amin N/A Nourmohammadi

Legacy Theses & Dissertations (2009 - 2024)

Brain’s electrophysiological signals are most certainly the ultimate source for studying the sophisticated neural network inside our cranium. The unparalleled complexity of these biosignalsis the quintessential manifestation of their underlying complicated neurophysiological processes. Studying brain signals on the cellular level provides valuable information regarding the brain’s electrophysiology on the small-scale. However, it is the remarkable network in the large-scale that gives rise to the brain’s extraordinary attributes and exceptional capabilities—perception, cognition, computation, and consciousness are all the emergent byproducts of the dynamic neuronal interactions on the network level. In this sense, the large-scale electrophysiological signals, recorded from the surface of …


Statistical Methods To Unravel Cortical Mechanism Of Perception And Response To Auditory Stimuli, Ladan Moheimanian Jan 2020

Statistical Methods To Unravel Cortical Mechanism Of Perception And Response To Auditory Stimuli, Ladan Moheimanian

Legacy Theses & Dissertations (2009 - 2024)

Behavioral responses to auditory stimuli have a critical role in our daily activities. The perception of these stimuli and the generation of appropriate behavioral responses requires the interaction of thousands of neurons in the auditory-motor pathways in the brain. Despite their importance, still many neuroscientific questions about these interactions are remained to be answered. This may result from the limitations of brain recordings as well as statistical methods to analyze brain recordings. In this dissertation, I investigated underlying mechanisms that govern these neural interactions in the auditory-motor pathways using novel statistical techniques applied to the brain recordings from the surface …


Development Of Dual Functional Dna/Rna Nanostructures For Drug Delivery, Vibhav Amit Valsangkar Jan 2020

Development Of Dual Functional Dna/Rna Nanostructures For Drug Delivery, Vibhav Amit Valsangkar

Legacy Theses & Dissertations (2009 - 2024)

In addition to the traditional biochemical functions, DNA and RNA have been increasingly studied as building blocks for the formation of various 2D and 3D nanostructures. DNA has emerged as a versatile building block for programmable self-assembly. DNA-based nanostructures have been widely applied in biosensing, bioimaging, drug delivery, molecular computation and macromolecular scaffolding. A variety of strategies have been developed to functionalize these nanostructures. The major advantage is that DNA is a very stable molecule and its base-pairing properties can be easily utilized to control and program the formation of desired nanostructures. In addition, some of these DNA/RNA nanostructures have …


Increasing Performance Of Classifiers For Ssvep-Based Brain-Computer Interfaces Using Extension Methods, Ethan Douglas Webster Jan 2020

Increasing Performance Of Classifiers For Ssvep-Based Brain-Computer Interfaces Using Extension Methods, Ethan Douglas Webster

Legacy Theses & Dissertations (2009 - 2024)

Brain-computer interfaces (BCI) provide an alternative communication method that does not require standard physical mediums (speech, typing, etc.). These systems have been implemented to provide additional communication and control options for people with certain motor disabilities. Classification is an important part of BCI systems and consists of inferring user commands from brain activity. Supervised classification methods often achieve higher accuracy, but unsupervised classification methods are useful when training is not practical for the user. This thesis focuses on unsupervised classification algorithms used for a BCI speller application and presents extensions for two existing classifiers that improve classification accuracy and thus …


Sequentially-Closed And Forward-Closed String Rewriting Systems, Yu Zhang Jan 2020

Sequentially-Closed And Forward-Closed String Rewriting Systems, Yu Zhang

Legacy Theses & Dissertations (2009 - 2024)

In this dissertation we introduce the new concept of sequentially-closed string rewriting systems which generalizes forward-closed string rewriting systems and monadic string rewriting systems. We also investigate subclasses and properties of finite and regular sequentially-closed systems and forward-closed systems.


Metal Filled Carbon Nanotubes In Radiation Therapy : Dose Enhancement Effect, Sarah Ashmeg Jan 2020

Metal Filled Carbon Nanotubes In Radiation Therapy : Dose Enhancement Effect, Sarah Ashmeg

Legacy Theses & Dissertations (2009 - 2024)

In this work, the radiation dose enhancement is studied using a novel method and material that has not been widely investigated, at the time of this publication. Radiation dose enhancement is a useful technique in the field of radiation therapy, especially when dealing with radioresistant cells. Ideally, it increases the dose to the desired site with no additional damage to organs at risk.


Using Systems Archetypes And Generic Structures To Support Water Resource Management Studies : The Case Of Cropping Pattern Change In New Mexico State, Babak Bahaddin Jan 2020

Using Systems Archetypes And Generic Structures To Support Water Resource Management Studies : The Case Of Cropping Pattern Change In New Mexico State, Babak Bahaddin

Legacy Theses & Dissertations (2009 - 2024)

A wide range of managerial problems are similar in nature, and yet they continuously appear in different forms and in different geographical locations. Compared to other sciences, it seems that in the field of management, managers have a hard time facing these similar problems. Part of this issues is caused by the extreme complexity of the systems and another part is caused by the lack of a universal language with which managers can communicate their lessons. This dissertation offers a set of tools that have been previously manufactured in systems science, and more specifically in System Dynamics.


Towards Machine Learning In Chemical Sensing : Milk Differentiation And Quality Control Through Two-Dimensional Nano-Sensor Array, Yu Sheng Chen Jan 2020

Towards Machine Learning In Chemical Sensing : Milk Differentiation And Quality Control Through Two-Dimensional Nano-Sensor Array, Yu Sheng Chen

Legacy Theses & Dissertations (2009 - 2024)

Herein, we developed a novel artificial tongue using machine learning and 12 nanoassemblies (2D-NAs) to identify and analyzed different kinds of milk beverages for quality control. This biomimetic sensor array was trained to “taste” different milk types as an “artificial tongue” which is the first time we demonstrated that this sensor array can be implemented to complex systems. Two-dimensional nanoparticles (2D-nps) and nine fluorescently labeled single stranded oligonucleotides (ssDNA) with different length and nucleobases were assembled to create 12 2D-NAs. The artificial tongue was deployed to identify and analyze five milk types. All five milk types were discriminated with 95% …


Invariant-Based Online Software Anomaly Detection And Selective Regression Testing, Yizhen Chen Jan 2020

Invariant-Based Online Software Anomaly Detection And Selective Regression Testing, Yizhen Chen

Legacy Theses & Dissertations (2009 - 2024)

Software has been extensively used in various domains to provide online services. With the growing popularity of these types of applications, the quality of the software has a great impact on many of our daily activities [1]. Reliable software executions that deliver expected outcomes are essential for quality services. Software is considered abnormal when its behavior deviates from what is expected at any point during its execution. When anomalous behavior propagates to an exit point of the software and produces an incorrect output or an unexpected termination of the execution, it is considered a software failure. An anomaly may or …


Exploration Of Efficient Scintillation Based On Inas Quantum Dots In A Gaas Matrix, Katherine Rose Dropiewski Jan 2020

Exploration Of Efficient Scintillation Based On Inas Quantum Dots In A Gaas Matrix, Katherine Rose Dropiewski

Legacy Theses & Dissertations (2009 - 2024)

Scintillation and optical properties of an integrated InAs/GaAs Quantum Dot (QD) Scintillation Detector were investigated to improve efficiency and reduce the decay time of luminescence. The photoluminescent properties of InAs QDs embedded in a GaAs matrix were studied as-grown by molecular beam epitaxy (MBE) on GaAs substrates, and on foreign substrates fabricated as thick (10-25 μm) waveguides. The luminescent efficiency of QDs as-grown on GaAs substrates were examined using photoluminescence (PL) measurements at room temperature and the thermal quenching of PL was analyzed by comparing the integrated PL intensities at 77K-400K. PL measurements were used to optimize QD AlAs capping, …