Digital Commons Network^™

Design Of Novel Drug Delivery System And Optimal Dosage Regimens, Kwang Seok Kim

Dissertations

Three representative drug delivery systems were analyzed to emphasize the roles of mathematical models and computer-aided simulations in pharmaceutical research. In the first project, a protocol was developed so that the optimal regimen, consisting of the intravenous boluses and subsequent infusion of theophylline, could be obtained once information on the pharmacokinetics became available. The method was based on a two-compartment model of the human body. A module was created and posted on a website for free access. The second project dealt with the transdermal heat-assisted delivery of corticosterone. Heat conduction and drug diffusion through the patch and the skin were …

Atomic And Electronic Structure Studies Of Nano-Structured Systems : Carbon And Related Materials, Sumit Saxena

Dissertations

Modeling in the framework of density functional theory has been conducted on carbon nanotubes and graphene nano-structures. The results have been extended to non-carbon systems such as boron nanostructures. Computational studies are complemented by experimental methods to refine the structural models and obtain a better understanding of the electronic structure.

It is observed that the zigzag edged bilayered graphene nanoribbons are highly unstable as compared to their armchair counterparts. A novel approach has been proposed for the patterning of chirality/diameter controlled single walled carbon nanotubes. Nanotube formation is found to be assisted by edge ripples along with the intrinsic edge …

Hardware Support For Real-Time Network Security And Packet Classification Using Field Programmable Gate Arrays, Nitesh Bhicu Guinde

Dissertations

Deep packet inspection and packet classification are the most computationally expensive operations in a Network Intrusion Detection (NID) system. Deep packet inspection involves content matching where the payload of the incoming packets is matched against a set of signatures in the database. Packet classification involves inspection of the packet header fields and is basically a multi-dimensional matching problem. Any matching in software is very slow in comparison to current network speeds. Also, both of these problems need a solution which is scalable and can work at high speeds. Due to the high complexity of these matching problems, only Field-Programmable Gate …

Properties And Device Applications Of Silicon And Silicon-Germanium Nanostructures With Different Dimensions, Han-Yun Chang

Dissertations

Defect-free crystalline Si/SiGe(Ge) nanostructures are demonstrated despite the 4% lattice mismatch between Si and Ge. The lattice mismatch-induced strain is sufficiently relaxed through the designed, cluster morphology, or nanowire (NW) structures. Future device applications of these nano structures require complete understanding of their structural, optical, electrical and thermal properties. This study explores these properties in two-dimensional (2D) Si/Si:B delta-doped multilayers, 2D Si/Si_1-xGe_x planar multilayers, three-dimensional (3D) Si/Si_1-xGe_{x cluster multilayers, one-dimensional (1D) Si NWs and 1D Si/Ge NW heterojunctions (HJs).}

Raman scattering and photoluminescence measurements show that by alternating heavily boron-doped layers with layers of …

The Floating Contract Between Risk-Averse Supply Chain Partners In A Volatile Commodity Price Environment, Mojisola Kike Otegbeye

Dissertations

In this dissertation, two separate but closely related decision making problems in environments of volatile commodity prices are addressed. In the first problem, a risk-averse commodity user's purchasing policy and his risk-neutral supplier's pricing decision, where the user can purchase his needs through contract with his supplier as well as directly from the spot market, are analyzed. The commodity user is assumed to be the supplier's sole client, and the supplier can always expand capacity, at a cost to the user, to accommodate the user's demand in excess of initially reserved capacity.

In the more generalized second problem, both parties …

Novel Micron- And Nano-Scale Energetic Materials For Advanced Gun Propulsion, Their Material Properties, And Their Effects On Ballistic Performance, Thelma Gatuz Manning

Dissertations

This dissertation focused on the investigation of novel materials that are both energetic and inert in their micron- and nano-scale crystalline form. The characterization of the materials properties and its effects on the ballistic performance when incorporated into a composite material were evaluated as a gun propellant for application in a future weapon system for the US Army. Some of these materials may find dual use in civilian applications. Applications in small and medium arms, artillery, tank, aircraft, and shipboard gun systems will all benefit from these advancements. Not only will gun system performance be improved for greater stand-off range …

Constitutive Modeling Of Glassy Memory Polymers, Mahesh Khanolkar

Dissertations

The aim of this research is to develop constitutive models for non-linear materials. Here, issues related for developing constitutive model for glassy shape memory polymers are addressed in detail. Shape memory polymers are novel material that can be easily formed into complex shapes, retaining memory of their original shape even after undergoing large deformations. The temporary shape is stable and return to the original shape is triggered by a suitable mechanism such heating the polymer above a transition temperature. Glassy shape memory polymers are called glassy because the temporary shape is fixed by the formation of a glassy solid, while …

Transport Mechanisms And Modeling Of Riser Reactor, Dawei Wang

Dissertations

Riser reactors are extensively employed in various industrial applications. In a riser reactor, the hydrodynamics is closely interacted with kinetic reactions. Common models for the performance prediction of riser reactors overlook this vital coupling effect, which not only miss the important reaction characteristics in the dense-phase transport regime of riser reactors but also misinterpret the kinetic properties via ad hoc adjustments. It is noted that the modeling of hydrodynamics in riser flows has major flaws in its predictability of phase transport in both dense-phase and accelerating regimes where most reactions occur. In addition, with the spray feeding of reactants at …

Formation Of Screen-Printed Contacts On Multicrystalline Silicon (Mc-Si) Solar Cells, Vishal R. Mehta

Dissertations

Commercial multicrystalline silicon (me-Si) solar cells use screen-printing process for depositing both the Ag paste based gridded front and Al based back (whole area) metal contacts.. This thesis relates to experimental and theoretical studies of contact formation mechanisms in silicon solar cells. Temperature distribution studies during optical processing by. attached thermocouples to cells indicates that the maximum temperature reached under the front silver metal is less. than 800°C; this is lower than the eutectic point of Ag-Si (≈835°C). An analysis of the interaction of Ag particles and Si via the constituents of glass is given. This mechanism leaches metallic ions …

Multi-Component Boron Coatings On Low Carbon Steel Aisi 1018, Naruemon Suwattananont

Dissertations

Boronizing and metalizing are thermo-chemical surface hardening treatments in which boron and metal atoms diffuse into the metal substrate forming metallic boride layers, providing complex properties of B-Me-Fe system.

To study multi-component boron coatings on low carbon steel AISI 1018, the simultaneous powder pack method of boronizing and metalizing was selected to perform the coatings. One B-Fe system and eight boron-metal (B-Me-Fe) systems from transition metals group IVB (Ti, Zr, Hf), group VB (Nb, Ta), and group VIB (Cr, Mo, W) were studied. The system specimens were thermo-chemically treated at 950°C for 4 hours in a crucible containing powder mixture …

Optimizing Integrated Service For A Transit Route With Heterogeneous Demand, Yavuz Yusuf Ulusoy

Dissertations

The methodology developed in this dissertation attempts to optimize integrated service that minimizes the total cost, including user and supplier costs, of a transit route with heterogeneous demand. While minimizing total cost, a set of practical constraints, such as capacity, operable fleet size and frequency conservation, are considered.

The research problem is presented in three scenarios, consisting of various service patterns (e.g., all-stop, short-turn and express) under heterogeneous demand. A logit-based model was used to estimate passenger transfer demand. An exhaustive search method was developed to find the optimal solutions for a simplified transit route with six stops, and a …

Mechanisms For Quality-Of-Service Provisioning In Networks With Extended Services, Zhen Qin

Dissertations

The emerging network traffic with various Quality-of-Service (QoS) requirements creates a demand for QoS service provisioning beyond the best effort service that Internet currently provides. QoS provisioning requires a framework that satisfies users' QoS and cost demand while maximizes benefits for network service providers. It is considered that QoS provisioning involves three issues: a) estimations of the network QoS performance, which can be achieved by performing network measurement; b) dissemination of the measured QoS states throughout the network with states exchanged among different network routers; and c) QoS routing. In this dissertation, these three issues are addressed.

In QoS networks, …

Coupled Simulation Of Loading And Response Of Columns Under Extreme Events, Navid H. Allahverdi

Dissertations

Forces imparted to structural columns during blast-induced loading depends on the shape and size of columns as well as on the intensity of the blast. Column's geometry - i.e., shape and size - influences the flow field around the column and consequently the flow field determines forces experienced by the column The main objective of this research is to estimate the forces imparted to columns in a blast event through studying the air flow field around columns

In this study, the physics of shock wave reflection and rarefaction waves are reviewed with application to describing the air flow around columns …

Target Localization In Mimo Radar Systems, Hana Godrich

Dissertations

MIMO (Multiple-Input Multiple-Output) radar systems employ multiple antennas to transmit multiple waveforms and engage in joint processing of the received echoes from the target. MIMO radar has been receiving increasing attention in recent years from researchers, practitioners, and funding agencies. Elements of MIMO radar have the ability to transmit diverse waveforms ranging from independent to fully correlated. MIMO radar offers a new paradigm for signal processing research. In this dissertation, target localization accuracy performance, attainable by the use of MIMO radar systems, configured with multiple transmit and receive sensors, widely distributed over an area, are studied. The Cramer-Rao lower bound …

Operating Characteristics Of Passenger Screening Processes And The Development Of A Paced Inspection System, Geraldine Kelly Leone

Dissertations

The airport checkpoint security screening (ACSS) system is an important line of defense against the introduction of dangerous objects into the U.S. aviation system. Recently, there has been much interest in modeling these systems and to derive operating parameters which optimize performance. In general there are two performance measures of interest (i) the waiting time of the arriving entities, and (ii) the allocated screening resources and its utilization. Clearly, the traveling public would like a zero waiting time, while airports are limited both in terms of space and resource capital. The arrival and exit entity in the ACSS system are …

Service Oriented Networking For Multimedia Applications In Broadband Wireless Networks, Ehsan Haghani Dogaheh

Dissertations

Extensive efforts have been focused on deploying broadband wireless networks. Providing mobile users with high speed network connectivity will let them run various multimedia applications on their wireless devices. In order to successfully deploy and operate broadband wireless networks, it is crucial to design efficient methods for supporting various services and applications in broadband wireless networks. Moreover, the existing "access-oriented" networking solutions are not able to fully address all the issues of supporting various applications with different quality of service requirements. Thus, "service-oriented" networking has been recently proposed and has gained much attention.

This dissertation discusses the challenges and possible …

Optimal Train Control On Various Track Alignments Considering Speed And Schedule Adherence Constraints, Kitae Kim

Dissertations

The methodology discussed in this dissertation contributes to the field of transit operational control to reduce energy consumption. Due to the recent increase in gasoline cost, a significant number of travelers are shifting from highway modes to public transit, which also induces higher transit energy consumption expenses.

This study presents an approach to optimize train motion regimes for various track alignments, which minimizes total energy consumption subject to allowable travel time, maximum operating speed, and maximum acceleration/deceleration rates. The research problem is structured into four cases which consist of the combinations of track alignments (e.g., single vertical alignment and mixed …

Resource Assignment In Short Life Technology Intensive (Slti) New Product Development (Npd), Randy A. Reagan

Dissertations

Enterprises managing multiple concurrent New Product Development (NPD) projects face significant challenges assigning staff to projects in order to achieve launch schedules that maximize financial returns. The challenge is increased with the class of Short Life Technology Intensive (SLTI) products characterized by technical complexity, short development cycles and short revenue life cycles. Technical complexity drives the need to assign staffing resources of various technical disciplines and skill levels. SLTI products are rapidly developed and launched into stationary market windows where the revenue life cycle is short and decreasing with any time-to-market delay. The SLTI-NPD project management decision is to assign …

Inter-Relationship Of Mechanical And Bio-Chemical Processes Governing The Settlement Of Municipal Solid Waste (Msw) Using The (C +H)/L Ratio, Joseph John Lifrieri

Dissertations

This research discusses the results of experimentation that determines the rates and magnitudes of consolidation and settlement of solid waste materials dependent upon their actual state of biodegradation decomposition and time in place. The state of decomposition of waste is determined by measuring its cellulose plus hemicellulose to lignin ratio ((C + H)/L). The samples were collected from bioreactors, at consecutive time intervals, to simulate states of decomposition.

Each sample was tested in consolidation to determine the value of the primary compression index C' _c, the secondary compression index "the inorganic creep rate" coefficient, C' _α, and the …

End-Of-Life Analysis Of Nanotechnology Products, Sun Olapiriyakul

Dissertations

Previous research has shown that thermodynamic properties including melting point and specific heat capacity of nanomaterials may be higher than that of their corresponding bulk materials. The melting point elevation and specific heat capacity enhancement of nanomaterials may result in increased energy consumption and waste gases emission at the end-of-life (EOL) stage where the products containing nanomaterials are recycled by high temperature metal recovery (HTMR) process.

In this dissertation, the effect of physical characteristics of nanomaterials, referred to as physicochemical parameters, on their melting temperature and specific heat capacity was investigated. In addition, physical, chemical, and thermodynamic properties of nanomaterials …

Cooperative Retransmission Protocols In Fading Channels : Issues, Solutions And Applications, Igor Stanojev

Dissertations

Future wireless systems are expected to extensively rely on cooperation between terminals, mimicking MIMO scenarios when terminal dimensions limit implementation of multiple antenna technology. On this line, cooperative retransmission protocols are considered as particularly promising technology due to their opportunistic and flexible exploitation of both spatial and time diversity. In this dissertation, some of the major issues that hinder the practical implementation of this technology are identified and pertaining solutions are proposed and analyzed. Potentials of cooperative and cooperative retransmission protocols for a practical implementation of dynamic spectrum access paradigm are also recognized and investigated. Detailed contributions follow.

While conventionally …

Optimal Synthesis Of Planar Adjustable Mechanisms, Chong Peng

Dissertations

Adjustable mechanisms provide degrees of flexibility while retaining desirable features of one degree of freedom close-loop mechanisms, such as simplicity, stability, and high speed capabilities. By adjusting linkage parameters, additional phases of motions can be achieved using the same hardware. However, an adjustment to the mechanism adds only one or two additional design positions and divides desired positions into "phases", each of which contains only a few positions usually insufficient for industrial applications.

In order to extend the design position limitation of adjustable mechanisms, an optimal synthesis method based on link length structural error is developed and applied to kinematic …

Soft-Error Resilient On-Chip Memory Structures, Shuai Wang

Dissertations

Soft errors induced by energetic particle strikes in on-chip memory structures, such as L1 data/instruction caches and register files, have become an increasing challenge in designing new generation reliable microprocessors. Due to their transient/random nature, soft errors cannot be captured by traditional verification and testing process due to the irrelevancy to the correctness of the logic. This dissertation is thus focusing on the reliability characterization and cost-effective reliable design of on-chip memories against soft errors.

Due to various performance, area/size, and energy constraints in various target systems, many existing unoptimized protection schemes on cache memories may eventually prove significantly inadequate …

Adaptive Trust And Reputation System As A Security Service In Group Communications, Pitipatana Sakarindr

Dissertations

Group communications has been facilitating many emerging applications which require packet delivery from one or more sender(s) to multiple receivers. Owing to the multicasting and broadcasting nature, group communications are susceptible to various kinds of attacks. Though a number of proposals have been reported to secure group communications, provisioning security in group communications remains a critical and challenging issue.

This work first presents a survey on recent advances in security requirements and services in group communications in wireless and wired networks, and discusses challenges in designing secure group communications in these networks. Effective security services to secure group communications are …

Synthesis And Characterization Of Metal Oxide Semiconductors For Photoelectrochemical Hydrogen Production, Sudhakar Shet

Dissertations

The goal of this thesis is to investigate the properties of metal-oxide thin films on fluorine-doped tin oxide (FTO)-coated glass substrates, prepared by using radio- frequency (RF) reactive magnetron sputtering for photoelectrochemical (PEC) applications. Metal-oxide thin films as a photoelectrode are of special interest for PEC systems to produce hydrogen in an aqueous solution by solar energy due to their low cost and potential stability.

The following list represents some of the accomplishments and results of this work:

• Narrowing of N-incorporated ZnO (ZnO:N) was achieved by reactive sputtering in a O₂/N₂ mixture ambient, and ZnO:N films with …

Generalized Discrete Fourier Transform With Non-Linear Phase : Theory And Design, Handan Agirman-Tosun

Dissertations

Constant modulus transforms like discrete Fourier transform (DFT), Walsh transform, and Gold codes have been successfully used over several decades in various engineering applications, including discrete multi-tone (DMT), orthogonal frequency division multiplexing (OFDM) and code division multiple access (CDMA) communications systems. Among these popular transforms, DFT is a linear phase transform and widely used in multicarrier communications due to its performance and fast algorithms. In this thesis, a theoretical framework for Generalized DFT (GDFT) with nonlinear phase exploiting the phase space is developed. It is shown that GDFT offers sizable correlation improvements over DFT, Walsh, and Gold codes. Brute force …

Motion Coordination And Control In The Development Of A Gait Rehabilitation System, Yazan Ahmad Manna

Dissertations

While most take their ability to walk for granted, some are unable to walk due to any number of pathologies, such as traumatic brain injury (TBI), spinal cord injury (SCI), and Parkinson's disease. Decreased activity has been shown to be associated with rapidly deconditioning. Rehabilitation techniques that afford patients the ability to begin reconditioning through walking sooner may ultimately enhance their return to a better quality of life. To assist the functional recovery of such patients, an appropriate afferent input to the spinal cord will help in the therapy of the patient. Manual training is labor intensive, costly, and ergonomically …

Advanced Classification Of Ofdm And Mimo Signals With Enhanced Second Order Cyclostationarity Detection, Miao Shi

Dissertations

With the emergence of cognitive radio and the introduction of new modulation techniques such as OFDM and MIMO, the problem of Modulation Classification (MC) becomes more challenging and complicated. In the first part of the thesis, we explore the automatic modulation classification to blindly distinguish OFDM from single carrier signals. We use the fourth order cumulants; an approach which in the past has been also applied to classify single carrier signals. A blind OFDM parameter estimation scheme was then followed, which includes the estimation of number of subcarriers, CP length, timing and frequency offset and the oversampling factor for the …