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Computational Simulation And Analysis Of Neuroplasticity, Madison E. Yancey
Computational Simulation And Analysis Of Neuroplasticity, Madison E. Yancey
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Homeostatic synaptic plasticity is the process by which neurons alter their activity in response to changes in network activity. Neuroscientists attempting to understand homeostatic synaptic plasticity have developed three different mathematical methods to analyze collections of event recordings from neurons acting as a proxy for neuronal activity. These collections of events are from control data and treatment data, referring to the treatment of neuron cultures with pharmacological agents that augment or inhibit network activity. If the distribution of control events can be functionally mapped to the distribution of treatment events, a better understanding of the biological processes underlying homeostatic synaptic …
Bayesian Inspired Multi-Fidelity Optimization With Aerodynamic Design, Christopher Corey Fischer
Bayesian Inspired Multi-Fidelity Optimization With Aerodynamic Design, Christopher Corey Fischer
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In most engineering design problems, there exist multiple models of varying fidelities for use in predicting a single system response such as Computational Fluid Dynamics (CFD) models constructed using Potential Flow, Euler equations, or full physics Navier Stokes implementation. Engineering design is constantly pushing the forefront of the field through imposing stricter and more complex constraints on system performance, thus elevating the need for use of high-fidelity models in the design process. Increasing fidelity level often correlates to an increase in cost (financial, computational time, and computational resources). Traditional design processes rely upon low-fidelity models for expedience and resource savings. …