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Design Of A Physical Windkessel Model For Use In Lvad In-Vitro Benchtop Modeling, Kyle W. Beggs
Design Of A Physical Windkessel Model For Use In Lvad In-Vitro Benchtop Modeling, Kyle W. Beggs
HIM 1990-2015
Despite improved life expectancy compared to medical management alone, Ventricular Assist Device (VAD) recipients show survival rates of 80% at 12 months and 70% at 24 months. A large portion of VAD-associated mortality results from increased risk of stroke with an event frequency reported between 14-47%. Recent concerns have been raised about unprecedented increases of thrombus formation in VAD recipients with subsequent reports pointing towards implantation techniques as a critical contributor to these events. Thus, the overall prognosis with mechanical support can improve by advancing the surgeon’s approach to VAD implantation. Previous studies using Computational Fluid Dynamics (CFD) were aimed …
Effects Of Binary Solvent System On Morphology Of Particles, Patrick Besana
Effects Of Binary Solvent System On Morphology Of Particles, Patrick Besana
HIM 1990-2015
Recent advancements in cancer research has led to the synthesis of a new drug known as docetaxel. Meant to replace paclitaxel, its more natural counterpart whose ingredients are difficult to obtain, the drug is known to effectively treat a wide array of cancers, including breast cancer, ovarian cancer, and prostate cancer. The establishment of a synthetic alternative to paclitaxel has increased its bioavailability, thereby lowering the cost needed to utilize the drug. Still, the limiting factor in minimizing costs is the method in which the drug is processed. Current methods in drug processing have their limitations, which include the introduction …
Development Of A Set Of Force Response Equations To Represent The Musculature In Infants To Study Development Dysplasia Of The Hip, Brendan Jones
Development Of A Set Of Force Response Equations To Represent The Musculature In Infants To Study Development Dysplasia Of The Hip, Brendan Jones
HIM 1990-2015
This paper describes how a force response equation was created to model muscles, tendons, and ligaments of the hip joint to improve a biomechanical model of an infant hip to study Developmental Dysplasia of the Hip (DDH). DDH is the most common abnormality in newborn infants and is defined as any amount of instability in the hip including complete dislocation. Researchers at our institution are attempting to increase the success rate of treatment methods by creating computer models of the biomechanics of infant hip instability and dislocation. The computer model used a scaled adult pelvis, femur, tibia, fibula and foot …
Dynamic Response Of A Multi-Span Curved Beam From Moving Transverse Point Loads, Amanda Alexander
Dynamic Response Of A Multi-Span Curved Beam From Moving Transverse Point Loads, Amanda Alexander
HIM 1990-2015
This thesis describes how to evaluate a first-order approximation of the vibration induced on a beam that is vertically curved and experiences a moving load of non-constant velocity. The curved beam is applicable in the example of a roller coaster. The present research in the field does not consider a curved beam nor can similar research be applied to such a beam. The complexity of the vibration of a curved beam lies primarily in the description of the variable magnitude of the moving load applied. Furthermore, this motion is also variable. This thesis will present how this beam will displace …
Hybrid Carbon Fiber Alumina Nanocomposite For Non-Contact Stress Sensing Via Piezospectroscopy, Imad Hanhan
Hybrid Carbon Fiber Alumina Nanocomposite For Non-Contact Stress Sensing Via Piezospectroscopy, Imad Hanhan
HIM 1990-2015
Carbon ber composites have become popular in aerospace structures and applications due to their light weight, high strength, and high performance. Recently, scientists have begun investigating hybrid composites that include fibers and particulate fillers, since they allow for advanced tailoring of mechanical properties, such as improved fatigue life. This project investigated a hybrid carbon ber reinforced polymer (HCFRP) that includes carbon fiber and additional alumina nanoparticle fillers, which act as embedded nano stress-sensors. Utilizing the piezospectroscopic e ect, the photo-luminescent spectral signal of the embedded nanoparticles has been monitored as it changes with stress, enabling non-contact stress detection of the …
Design And Evaluation Of A Test Platform For Thermal Mechanical And Acoustical Loading, Abdi Jasmin
Design And Evaluation Of A Test Platform For Thermal Mechanical And Acoustical Loading, Abdi Jasmin
HIM 1990-2015
Next generation hypersonic cruise vehicle components will be subjected to a collection of loads not achievable in contemporary mechanical test platform. The purpose of this thesis is to demonstrate the design of a unique test platform for combined extreme environment (P-CEEn) needed to replicate thermal, acoustic and mechanical loading to be imparted on hypersonic fuselage panels. The panels are typically subjected to super-imposed cycling from hypersonic shock/impingement and aerodynamic pressure from the usual ascent-cruise-decent motion of the aircrafts combined with mechanical vibration at acoustic frequencies; moreover, these slender components will undergo conventional mechanical fatigue with compressive mean stress due to …
Frequency-Domain Faraday Rotation Spectroscopy (Fd-Frs) For Functionalized Particle And Biomolecule Characterization, Richard Murdock
Frequency-Domain Faraday Rotation Spectroscopy (Fd-Frs) For Functionalized Particle And Biomolecule Characterization, Richard Murdock
HIM 1990-2015
In this study, the magnetically-induced vibrations of functionalized magnetic particle suspensions were probed for the development of a novel optical spectroscopy technique. Through this work (1) the frequency-dependence of the faraday rotation in ferrofluids and (2) the extension of this system to elucidating particle size and conformation as an alternative immunossay to costly and labor/time intensive Western Blotting and ELISA has been shown. With its sensitivity and specificity, this method has proven to be a promising multi-functional tool in biosensing, diagnostic, and therapeutic nanomedicine efforts. Due to its ubiquitous nature in all optically-transparent materials, the farady rotation, or circular birefringence, …
Understanding And Modeling Pathways To Thrombosis, John Seligson
Understanding And Modeling Pathways To Thrombosis, John Seligson
HIM 1990-2015
This research will investigate techniques to create a sensor that is responsive to methane at 23°C. The approach will use the integration of a very thin film, which changes its resistive properties when methane gas is applied, deposited atop the surface of a piezoelectric substrate. An aluminum thin film interdigital transducer will launch a surface acoustic wave (SAW) that travels under the sensor’s gas-sensitive resistive thin film. The SAW/resistive film interaction changes the SAW amplitude, phase and delay. For this work, three films, tin dioxide (SnO2), zinc oxide (ZnO) and palladium (Pd) [1, 2] will be studied. Gas detection will …
Nanocluster Thin-Films For Sensor Applications, Joseph Serritella
Nanocluster Thin-Films For Sensor Applications, Joseph Serritella
HIM 1990-2015
The ability to sense gas such as methane can provide an early warning system to protect human lives. High demand for the ability to sense the world around us has provided an extensive area of research for sensor technology. In particular, current sensor technology, specifically for methane, has provided sensors that require a heated environment to function. The majority of current methane sensors function at temperatures between 150°C and 450°C [1-3]. This thesis will explore an approach to produce a room temperature methane sensor.
A Laboratory Scale Assessment Of The Effect Of Chlorine Dioxide Pre-Oxidation On Disinfection By-Product Formation For Two Surface Water Supplies, Angela Rodriguez
A Laboratory Scale Assessment Of The Effect Of Chlorine Dioxide Pre-Oxidation On Disinfection By-Product Formation For Two Surface Water Supplies, Angela Rodriguez
HIM 1990-2015
Chemical disinfection is the cornerstone of safe drinking water. However, the use of chemical disinfection results in the unintentional formation of disinfection by-products (DBPs), an outcome of reactions between the disinfectant and natural organic matter (NOM) present in the native (raw) water. DBPs are suspected carcinogens, and as such, have been regulated by the U.S. Environmental Protection Agency (USEPA) under the Safe Drinking Water Act (SDWA). This document reports the results of a study that investigated the use of chlorine dioxide pre-oxidation for the reduction of DBP precursors, and subsequently, DBP formation potential (FP). To determine the effectiveness of the …
A Mechanics-Based Approach For Putt Distance Optimization, Pascual Santiago-Martinez
A Mechanics-Based Approach For Putt Distance Optimization, Pascual Santiago-Martinez
HIM 1990-2015
Quantifying the core mechanics of putting is imperative to developing a reliable model that predicts post-collision ball behavior. A preliminary model for the stroking motion of putting and putter-ball collision is developed alongside experiments, establishing an empirical model that supports the theory. The goal of the present study is to develop a correlation between the backstroke of a putt, or the pre-impact translation of the putter, and the post-impact displacement of the golf ball. This correlation is subsequently utilized to generate an algorithm that predicts the two-dimensional ball trajectory based on putt displacement and putting surface texture by means of …
Broadband Coherent Perfect Absorption In One-Dimensional Optical Systems, Massimo Maximilian Villinger
Broadband Coherent Perfect Absorption In One-Dimensional Optical Systems, Massimo Maximilian Villinger
Electronic Theses and Dissertations
Absorption plays a critical role in a variety of optical applications – sometimes it is desirable to minimize it as in optical fibers and waveguides, or to enhance it as in solar cells and photodetectors. We describe here a new optical scheme that controllably produces high optical absorption over a broad wavelength range (hundreds of nm) in systems that have low intrinsic absorption over the same range. This effect, 'coherent perfect absorption' or CPA, arises from a subtle interplay between interference and absorption of two beams incident on a weakly absorbing medium. In the first part of this study, we …
Nanoarchitectured Energy Storage Devices, Zenan Yu
Nanoarchitectured Energy Storage Devices, Zenan Yu
Electronic Theses and Dissertations
Supercapacitors, the devices that connect the gap between batteries and conventional capacitors, have recently attracted significant attention due to their high specific capacitance, substantially enhanced power and energy densities, and extraordinary cycle life. In order to realize even better performance with supercapacitors, rejuvenated effort towards developing nanostructured electrodes is necessary. In this dissertation, several strategic directions of nanoarchitecturing the electrodes to enhance the performance of supercapacitors are investigated. An introduction and background of supercapacitors, which includes motivation, classification and working principles, recent nanostructured electrode materials studies, and devices fabrication, are initially presented. A facile method, called Spin-on Nanoprinting (SNAP), to …
Drinking Water Infrastructure Assessment With Teleconnection Signals, Satellite Data Fusion And Mining, Sanaz Imen
Drinking Water Infrastructure Assessment With Teleconnection Signals, Satellite Data Fusion And Mining, Sanaz Imen
Electronic Theses and Dissertations
Adjustment of the drinking water treatment process as a simultaneous response to climate variations and water quality impact has been a grand challenge in water resource management in recent years. This desired and preferred capability depends on timely and quantitative knowledge to monitor the quality and availability of water. This issue is of great importance for the largest reservoir in the United States, Lake Mead, which is located in the proximity of a big metropolitan region - Las Vegas, Nevada. The water quality in Lake Mead is impaired by forest fires, soil erosion, and land use changes in nearby watersheds …
Assessing Approximate Arithmetic Designs In The Presence Of Process Variations And Voltage Scaling, Adnan Aquib Naseer
Assessing Approximate Arithmetic Designs In The Presence Of Process Variations And Voltage Scaling, Adnan Aquib Naseer
Electronic Theses and Dissertations
As environmental concerns and portability of electronic devices move to the forefront of priorities, innovative approaches which reduce processor energy consumption are sought. Approximate arithmetic units are one of the avenues whereby significant energy savings can be achieved. Approximation of fundamental arithmetic units is achieved by judiciously reducing the number of transistors in the circuit. A satisfactory tradeoff of energy vs. accuracy of the circuit can be determined by trial-and-error methods of each functional approximation. Although the accuracy of the output is compromised, it is only decreased to an acceptable extent that can still fulfill processing requirements. A number of …
Post Conversion Correction Of Non-Linear Mismatches For Time Interleaved Analog-To-Digital Converters, Charna Parkey
Post Conversion Correction Of Non-Linear Mismatches For Time Interleaved Analog-To-Digital Converters, Charna Parkey
Electronic Theses and Dissertations
Time Interleaved Analog-to-Digital Converters (TI-ADCs) utilize an architecture which enables conversion rates well beyond the capabilities of a single converter while preserving most or all of the other performance characteristics of the converters on which said architecture is based. Most of the approaches discussed here are independent of architecture; some solutions take advantage of specific architectures. Chapter 1 provides the problem formulation and reviews the errors found in ADCs as well as a brief literature review of available TI-ADC error correction solutions. Chapter 2 presents the methods and materials used in implementation as well as extend the state of the …
A Multi-Scale Cfd Analysis Of Patient-Specific Geometries To Tailor Lvad Cannula Implantation Under Pulsatile Flow Conditions: An Investigation Aimed At Reducing Stroke Incidence In Lvads, Ray Prather
Electronic Theses and Dissertations
A Left Ventricular Assist Device (LVAD) is a mechanical pump that provides temporary circulatory support when used as bridge-to-transplantation and relieves workload demand placed on a failing heart allowing for myocardia recovery when used as destination therapy. Stroke is the most devastating complication after ventricular assist device (VAD) implantation, with an incidence of 14-47% over 3-6 months. This complication due to thrombus formation and subsequent transport through the vasculature to cerebral vessels continues to limit the widespread implementation of VAD therapy. Patient-specific computational fluid dynamics (CFD) analysis may elucidate ways to reduce this risk. We employed a multi-scale model of …
Reasoning Tradeoffs In Implicit Invocation And Aspect Oriented Languages, Jose Sanchez Salazar
Reasoning Tradeoffs In Implicit Invocation And Aspect Oriented Languages, Jose Sanchez Salazar
Electronic Theses and Dissertations
To reason about a program means to state or conclude, by logical means, some properties the program exhibits; like its correctness according to certain expected behavior. The continuous need for more ambitious, more complex, and more dependable software systems demands for better mechanisms to modularize them and reason about their correctness. The reasoning process is affected by the design decisions made by the developer of the program and by the features supported by the programming language used. Beyond Object Orientation, Implicit Invocation and Aspect Oriented languages pose very hard reasoning challenges. Important tradeoffs must be considered while reasoning about a …
A Framework For Safety Training Using Virtual Reality Software, Rana Riad
A Framework For Safety Training Using Virtual Reality Software, Rana Riad
Electronic Theses and Dissertations
Safety training is a vital component to the well-being of individuals in all industries. With technology advancing at the current pace, conventional training methods are no longer the most effective way to communicate information. There is a strong need for safety training that incorporates new methods and forms of communication to obtain higher levels of comprehension. Virtual reality systems offer a highly customizable and interactive form of delivering information to users. This research addresses major gaps in the field of safety training using virtual reality systems and provides a design framework for creating a virtual safety-training system. A model for …
True Linearized Intensity Modulation For Photonic Analog To Digital Conversion Using An Injection-Locked Mode-Locked Laser, Edris Sarailou
True Linearized Intensity Modulation For Photonic Analog To Digital Conversion Using An Injection-Locked Mode-Locked Laser, Edris Sarailou
Electronic Theses and Dissertations
A true linearized interferometric intensity modulator for pulsed light has been proposed and experimentally presented in this thesis. This has been achieved by introducing a mode-locked laser into one of the arms of a Mach-Zehnder interferometer and injection-locking it to the input light (which is pulsed and periodic). By modulating the injection-locked laser, and combining its output light with the light from the other arm of interferometer in quadrature, one can achieve true linearized intensity modulator. This linearity comes from the arcsine phase response of the injection-locked mode-locked laser (as suggested by steady-state solution of Adler's equation) when it is …
Trihalomethane Removal And Re-Formation In Spray Aeration Processes Treating Disinfected Groundwater, Cassandra Smith
Trihalomethane Removal And Re-Formation In Spray Aeration Processes Treating Disinfected Groundwater, Cassandra Smith
Electronic Theses and Dissertations
Historically, chlorination has been widely utilized as a primary and secondary disinfectant in municipal water supplies. Although chlorine disinfection is effective in inactivating pathogenic microbes, the use of chlorine creates the unintentional formation of regulated chemicals. On January 4, 2006, the United States Environmental Protection Agency (EPA) promulgated the Stage 2 Disinfectants/Disinfection by-product rule (DBPR) that focuses on public health protection by limiting exposure to four trihalomethanes (THM) and five haloacetic acids (HAA5), formed when chlorine is used for microbial pathogen control. This thesis examines post-aeration TTHM formation when employing spray-aeration processes to remove semi-volatile TTHMs from chlorinated potable water …
Improving Fairness, Throughput And Blocking Performance For Long Haul And Short Reach Optical Networks, Sana Tariq
Improving Fairness, Throughput And Blocking Performance For Long Haul And Short Reach Optical Networks, Sana Tariq
Electronic Theses and Dissertations
Innovations in optical communication are expected to transform the landscape of global communications, internet and datacenter networks. This dissertation investigates several important issues in optical communication such as fairness, throughput, blocking probability and differentiated quality of service (QoS). Novel algorithms and new approaches have been presented to improve the performance of optical circuit switching (OCS) and optical burst switching (OBS) for long haul, and datacenter networks. Extensive simulations tests have been conducted to evaluate the effectiveness of the proposed algorithms. These simulation tests were performed over a number of network topologies such as ring, mesh and U.S. Long-Haul, some high …
Meshless Direct Numerical Simulation Of Turbulent Incompressible Flows, Andres Vidal Urbina
Meshless Direct Numerical Simulation Of Turbulent Incompressible Flows, Andres Vidal Urbina
Electronic Theses and Dissertations
A meshless direct pressure-velocity coupling procedure is presented to perform Direct Numerical Simulations (DNS) and Large Eddy Simulations (LES) of turbulent incompressible flows in regular and irregular geometries. The proposed method is a combination of several efficient techniques found in different Computational Fluid Dynamic (CFD) procedures and it is a major improvement of the algorithm published in 2007 by this author. This new procedure has very low numerical diffusion and some preliminary calculations with 2D steady state flows show that viscous effects become negligible faster that ever predicted numerically. The fundamental idea of this proposal lays on several important inconsistencies …
Traffic Conflict Analysis Under Fog Conditions Using Computer Simulation, Binya Zhang
Traffic Conflict Analysis Under Fog Conditions Using Computer Simulation, Binya Zhang
Electronic Theses and Dissertations
The weather condition is a crucial influence factor on road safety issues. Fog is one of the most noticeable weather conditions, which has a significant impact on traffic safety. Such condition reduces the road's visibility and consequently can affect drivers' vision, perception, and judgments. The statistical data shows that many crashes are directly or indirectly caused by the low-visibility weather condition. Hence, it is necessary for road traffic engineers to study the relationship of road traffic accidents and their influence factors. Among these factors, the traffic volume and the speed limits in poor visibility areas are the primary reasons that …
Development Of Regional Optimization And Market Penetration Models For Electric Vehicles In The United States, Mehdi Noori
Development Of Regional Optimization And Market Penetration Models For Electric Vehicles In The United States, Mehdi Noori
Electronic Theses and Dissertations
Since the transportation sector still relies mostly on fossil fuels, the emissions and overall environmental impacts of the transportation sector are particularly relevant to the mitigation of the adverse effects of climate change. Sustainable transportation therefore plays a vital role in the ongoing discussion on how to promote energy insecurity and address future energy requirements. One of the most promising ways to increase energy security and reduce emissions from the transportation sector is to support alternative fuel technologies, including electric vehicles (EVs). As vehicles become electrified, the transportation fleet will rely on the electric grid as well as traditional transportation …
Safety Climate And Safety Outcomes In Aircraft Maintenance: A Mediating Effect Of Employee Turnover And Safety Motivation, Muhanna Alnoaimi
Safety Climate And Safety Outcomes In Aircraft Maintenance: A Mediating Effect Of Employee Turnover And Safety Motivation, Muhanna Alnoaimi
Electronic Theses and Dissertations
Aircraft maintenance is viewed as a critical safety component in general and military aviation industries, and thus it is crucial to identify the factors that may affect aircraft maintenance. Because the safety climate is considered as a leading indicator of safety performance and safety outcomes, this study utilized this safety climate approach to develop a model which can explain the relationships between employee turnover, safety motivation, self-reported unsafe acts, reporting unsafe behaviors, incidents, and injuries in the aviation maintenance environment. This study included a sample of 283 technicians in military aircraft maintenance units who participated in a cross-sectional random survey. …
Exploring Techniques For Providing Privacy In Location-Based Services Nearest Neighbor Query, John-Charles Asanya
Exploring Techniques For Providing Privacy In Location-Based Services Nearest Neighbor Query, John-Charles Asanya
Electronic Theses and Dissertations
Increasing numbers of people are subscribing to location-based services, but as the popularity grows so are the privacy concerns. Varieties of research exist to address these privacy concerns. Each technique tries to address different models with which location-based services respond to subscribers. In this work, we present ideas to address privacy concerns for the two main models namely: the snapshot nearest neighbor query model and the continuous nearest neighbor query model. First, we address snapshot nearest neighbor query model where location-based services response represents a snapshot of point in time. In this model, we introduce a novel idea based on …
Catalytic Role Of Boron Nitride In The Thermal Decomposition Of Ammonium Perchlorate, Kevin Grossman
Catalytic Role Of Boron Nitride In The Thermal Decomposition Of Ammonium Perchlorate, Kevin Grossman
Electronic Theses and Dissertations
The decomposition of Ammonium Perchlorate (AP), a strong oxidizer used in solid rocket propellant, is widely studied in an attempt to increase the burn characteristics of propellants. Many materials have been shown to catalyze its decomposition, but little is known about the mechanism by which AP decomposition becomes catalyzed. In this study, Boron Nitride (BN) nanostructures, a material previously unknown to act as a catalyst, is studied. The decomposition reaction is studied by thermo-gravimetric analysis / differential scanning calorimetry, X-ray photoelectron spectroscopy, fourier transform infrared spectroscopy, transmission electron microscopy and scanning electron microscopy. The goal of this study is to …
Design, Fabrication, And Interrogation Of Integrated Wireless Saw Temperature Sensors, Mark Gallagher
Design, Fabrication, And Interrogation Of Integrated Wireless Saw Temperature Sensors, Mark Gallagher
Electronic Theses and Dissertations
Wireless surface acoustic wave (SAW) sensors offer unique advantages over other sensor technologies because of their inherent ability to operate in harsh environments and completely passive operation, providing a reliable, maintenance-free life cycle. For certain SAW sensor applications the challenge is building a wirelessly interrogatable device with the same lifetime as the SAW substrate. The design of these application intensive sensors is complicated by the degradation of device bond wires, die adhesive, and antenna substrate. In an effort to maximize the benefits of the platform, this dissertation demonstrates wafer-level integrated SAW sensors that directly connect the thin film SAW to …
Liquid Crystal-Based Biosensors For The Detection Of Bile Acids, Sihui He
Liquid Crystal-Based Biosensors For The Detection Of Bile Acids, Sihui He
Electronic Theses and Dissertations
Bile acids are physiologically important metabolites, which are synthesized in liver as the end products of cholesterol metabolism and then secreted into intestine. They are amphiphilic molecules which play a critical role in the digestion and absorption of fats and fat-soluble vitamins through emulsification. The concentration of bile acids is an indicator for liver function. Individual suffering from liver diseases has a sharp increase in bile acid concentrations. Hence, the concentration level of bile acids has long been used as a biomarker for the early diagnosis of intestinal and liver diseases. Conventional methods of bile acid detection such as chromatography-mass …