Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network

Open Access. Powered by Scholars. Published by Universities.®

Engineering

PDF

Santa Clara University

Series

Optimization

Articles 1 - 2 of 2

Full-Text Articles in Entire DC Network

Sustainable, Alginate-Based Sensor For Detection Of Escherichia Coli In Human Breast Milk, Nicholas Kikuchi, Margaret May, Matthew Zweber, Jerard Madamba, Craig M. Stephens, Unyoung Kim, Maryam Mobed-Miremadi Feb 2020

Sustainable, Alginate-Based Sensor For Detection Of Escherichia Coli In Human Breast Milk, Nicholas Kikuchi, Margaret May, Matthew Zweber, Jerard Madamba, Craig M. Stephens, Unyoung Kim, Maryam Mobed-Miremadi

Bioengineering

There are no existing affordable diagnostics for sensitive, rapid, and on-site detection of pathogens in milk. To this end, an on-site colorimetric-based sustainable assay has been developed and optimized using an L16 (54) Taguchi design to obtain results in hours without PCR amplification. To determine the level of Escherichia coli (E. coli) contamination, after induction with 150 µL of breast milk, the B-Per bacterial protein extraction kit was added to a solution containing an alginate-based microcapsule assay. Within this 3 mm spherical novel sensor design, X-Gal (5-Bromo-4-Chloro-3-Indolyl β-D-Galactopyranoside) was entrapped at a concentration of 2 …


Best Trade-Off Point Method For Efficient Resource Provisioning In Spark, Peter P. Nghiem Nov 2018

Best Trade-Off Point Method For Efficient Resource Provisioning In Spark, Peter P. Nghiem

Computer Science and Engineering

Considering the recent exponential growth in the amount of information processed in Big Data, the high energy consumed by data processing engines in datacenters has become a major issue, underlining the need for efficient resource allocation for more energy-efficient computing. We previously proposed the Best Trade-off Point (BToP) method, which provides a general approach and techniques based on an algorithm with mathematical formulas to find the best trade-off point on an elbow curve of performance vs. resources for efficient resource provisioning in Hadoop MapReduce. The BToP method is expected to work for any application or system which relies on a …