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Articles 1 - 12 of 12
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Lipids Affect The Diffusion Of Estradiol In Osteonal Bone, Nicholas Anthony Cimino
Lipids Affect The Diffusion Of Estradiol In Osteonal Bone, Nicholas Anthony Cimino
ETD Archive
In healthy osteonal bone, embedded osteocytes form an intercellular communication network through overlapping cell membrane extensions, possibly defining an overlooked and clinically relevant lipid-mediated transport pathway for nonpolar molecules. Previous techniques evaluating solute transport in cortical bone limit tissue analysis to microscale areas (less than 1 mm2) using tracers and assumptions that diminish clinical relevance, presenting the need for an improved method to evaluate solute diffusion in macroscale areas (greater than 1 mm2) of osteonal bone. A new diffusion system - constructed of glass and polytetrafluoroethylene - was designed and validated for this purpose, exhibiting minimal adsorption of solutes and …
Predictions Of Indentation Stiffness Of Musculoskeletal Regions Using Ultrasound, Sean Doherty
Predictions Of Indentation Stiffness Of Musculoskeletal Regions Using Ultrasound, Sean Doherty
ETD Archive
Tissue indentation response is an important metric for understanding how different musculoskeletal regions respond to loading and is a function of the tissue’s form. Modem imaging techniques provide information about the internal structures of human tissue. Ultrasound remains one of the most common imaging techniques performed, given its portability and low costs. Prior work and data collection on 100 patients involved the collection of ultrasound images at eight different locations across the musculoskeletal extremities. Given the tissue structure information that the medical imaging provided, it was hypothesized that the mechanical properties of the tissue could be predicted from this data. …
Utilizing Simulated Vehicle Trajectory Data From Connected Vehicles To Characterize Performance Measures On An Arterial After An Impactful Incident, Norris Kamugisha Novat Baraba
Utilizing Simulated Vehicle Trajectory Data From Connected Vehicles To Characterize Performance Measures On An Arterial After An Impactful Incident, Norris Kamugisha Novat Baraba
ETD Archive
Traffic incidents are unforeseen events known to affect traffic flow because they reduce the capacity of an arterial corridor segment and normally generate a temporary bottleneck. Identification of retiming requirements to enhance traffic signal operations when an incident occurs depends on operations-oriented traffic signal performance measurements. When effective and real-time traffic signal performance metrics are employed at traffic control centers, delays, fuel use, and air pollution may all be decreased. The majority of currently available traffic signal performance evaluations are based on high-resolution traffic signal controller event data, which gives data on an intersection-by-intersection basis but requires a substantial upfront …
Strengthening Effects Of Carbon Nanotubes And Graphene Nanoplatelets Reinforced Nickel Metal Matrix Composites, Amit Patil
ETD Archive
Carbon nanotubes (CNTs) and graphene nanoplatelets (GNPs) with superior mechanical, thermal, chemical, and electrical properties are appealing reinforcements for the fabrication of lightweight, high-strength, and wear-resistant metal matrix composites with outstanding mechanical and tribological performance. The nickel-carbon nanotube composites (Ni-CNT) and nickel-graphene nano-platelet composites (Ni-GNP) were processed using two separate ball milling methods, namely dry ball milling (DM) and solution ball milling (SBM), and then sintered using the spark plasma sintering (SPS) technique. The influence of the premixing process, milling time, reinforcement morphology, and concentration on matrix grain size, microstructure, dispersion in the nickel matrix, mechanical properties, and tribological performance …
An Ultrasensitive Bacterial Detection Platform For Culture-Free Diagnosis Of Infections, Xuyang Shi
An Ultrasensitive Bacterial Detection Platform For Culture-Free Diagnosis Of Infections, Xuyang Shi
ETD Archive
The current methods of the diagnosis of bloodstream infections are based on bacterial culture growth, a process that requires considerable time, e.g., 12-16 hours, to obtain a result. This long wait time for the result creates many problems, including the generation of multi-drug resistant organisms (MDROs). At the same time, infected bloodstream usually contains a very low concentration of bacteria, i.e., lower than 5 CFU/mL. The long diagnosis time and the extremely low concentration of bacteria in the infected bloodstream make such infections difficult to diagnose. Here, we demonstrate a culture-free approach for the diagnosis of bloodstream infections using a …
Mechanistic Understanding Of Phase Stability, Transformation, And Strengthening Mechanisms In Lightweight High Entropy Alloys And High Entropy Ceramics, Ganesh Walunj
ETD Archive
High-entropy alloys (HEAs) are a novel family of solid-solution alloys that have gained international interest due to their exceptional characteristics. Because of the need from the transportation and defense sectors, lightweight HEAs have attracted researcher’s curiosity as prospective advanced materials. Low-weight high entropy alloy synthesizes using arc melting with a mass ratio of AlCrFeMnTix(0.1,0.15,0.2). The synthesized HEA is comprised of a mixture of body center cubic (bcc) and ordered bcc (L21) solid solution phases. The synthesized HEAs have heat treated at 650C, 800C, and 1150C for 1hr, 4hr after solutionized at 1150C for 2 hr to understand the effect of …
An Improved Polynomial Chaos Expansion Based Response Surface Method And Its Applications On Frame And Spring Engineering Based Structures, Mhd A. Hafez
ETD Archive
In engineering fields, computational models provide a tool that can simulate a real world response and enhance our understanding of physical phenomenas. However, such models are often computationally expensive with multiple sources of uncertainty related to the model’s input/assumptions. For example, the literature indicates that ligament’s material properties and its insertion site locations have a significant effect on the performance of knee joint models, which makes addressing uncertainty related to them a crucial step to make the computational model more representative of reality. However, previous sensitivity studies were limited due to the computational expense of the models. The high computational …
Development, Characterization, And Modeling Of Physical, Mechanical, And Durability Properties Of Sustainable Ultra-High Performance Concrete, Tawsif M. Hasan
Development, Characterization, And Modeling Of Physical, Mechanical, And Durability Properties Of Sustainable Ultra-High Performance Concrete, Tawsif M. Hasan
ETD Archive
Ultra-High Performance Concrete (UHPC) is an advanced concrete material with superior mechanical strength, high tensile ductility, and exceptional durability, including negligible permeability. Despite these excellent material properties, the use of UHPC in structural applications is limited because of the high cost of commercially available UHPC products. Therefore, developing non-proprietary UHPC mixtures using local materials is a viable way to reduce the initial cost of UHPC. In this research, sustainable and cost-effective UHPC mixtures were developed using locally sourced materials so that UHPC may be more affordable to a wider variety of applications. Specifically, locally available Type I-II cement, local sand …
Mechanistic Undrestanding Of Amorphization In Iron-Based Soft Magnetic Materials, Taban Larimian
Mechanistic Undrestanding Of Amorphization In Iron-Based Soft Magnetic Materials, Taban Larimian
ETD Archive
Iron-based magnetic alloys possess very good magnetic and mechanical properties. Among these alloys Fe-Si-B-based alloys show outstanding saturation magnetization and coercivity which makes them great candidates for many industrial applications. Addition of certain elements to the Fe-Si-B base is proven to improve the homogeneity and fineness of microstructure as well as enhance the magnetic behavior of these alloys. In this research work, we have studied the effect of adding copper and niobium to the Fe-Si-B base alloy. Previous studies have shown that magnetic alloys show better magnetic properties when their microstructure consists of nanocrystals embedded in an amorphous matrix. In …
Viability And Accessibility Of Urban Heat Island And Lake Microclimate Data Over Current Tmy Weather Data For Accurate Energy Demand Predictions., Irena A. Weclawiak
Viability And Accessibility Of Urban Heat Island And Lake Microclimate Data Over Current Tmy Weather Data For Accurate Energy Demand Predictions., Irena A. Weclawiak
ETD Archive
Building Energy Simulations (BES) are necessary for designing energy-efficient systems. Open-source simulation software developed by the Department of Energy (DOE), EnergyPlus (EP) provides Typical Meteorological Year (TMY) weather data that consists of a 15-year average. Two major concerns about this data are the inability to detect extreme conditions and limited data locations. There is a greater number of Microclimate (MC) stations that can be used for simulations, but it involves time-consuming data preparation to match the EP format. This study investigated the effects of Urban Heat Island (UHI) and the MC of Lake Erie. A comparison of the MC data …
An Evaluation And Economic Analysis Of A Water Main Geothermal System In A Residential Space, Brian L. Kohut
An Evaluation And Economic Analysis Of A Water Main Geothermal System In A Residential Space, Brian L. Kohut
ETD Archive
Iron-based magnetic alloys possess very good magnetic and mechanical properties. Among these alloys Fe-Si-B-based alloys show outstanding saturation magnetization and coercivity which makes them great candidates for many industrial applications. Addition of certain elements to the Fe-Si-B base is proven to improve the homogeneity and fineness of microstructure as well as enhance the magnetic behavior of these alloys. In this research work, we have studied the effect of adding copper and niobium to the Fe-Si-B base alloy. Previous studies have shown that magnetic alloys show better magnetic properties when their microstructure consists of nanocrystals embedded in an amorphous matrix. In …
An Analytical Methodology To Security Constraints Management In Power System Operation, Shubo Zhang
An Analytical Methodology To Security Constraints Management In Power System Operation, Shubo Zhang
ETD Archive
In a deregulated electricity market, Independent System Operators (ISOs) are responsible for dispatching power to the load securely, efficiently, and economically. ISO performs Security Constrained Unit Commitment (SCUC) to guarantee sufficient generation commitment, maximized social welfare and facilitating market-driven economics. A large number of security constraints would render the model impossible to solve under time requirements. Developing a method to identify the minimum set of security constraints without overcommitting is necessary to reduce Mixed Integer Linear Programming (MILP) solution time. To overcome this challenge, we developed a powerful tool called security constraint screening. The proposed approach effectively filters out non-dominating …