Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 5 of 5
Full-Text Articles in Entire DC Network
Design Of A Multidirectional Wear Testing Device For Simulating Wear Of Biocompatible Materials Used In Joint Implants, Carlos A. Rodriguez Betancourth
Design Of A Multidirectional Wear Testing Device For Simulating Wear Of Biocompatible Materials Used In Joint Implants, Carlos A. Rodriguez Betancourth
Theses and Dissertations
In the present work, a novel multidirectional pin-on-disc wear testing device designated CNC-POD (computer-numerical-control pin-on-disc) capable of replicating the cross-shear motions experienced by a prosthesis in vivo was designed and developed in the UTRGV in order to evaluate the wear resistance of new biomaterials. The CNC-POD consists of six temperature-controlled pin-on-disc stations mounted on a two-axis CNC table (X-Y). Each pin-on-disc station is load-programmable up to 510 Newtons (115 pounds). The CNC table allows the machine to reproduce a wide range of 2D patterns in millimeter scale on the six stations under a specific load. Friction force is measured during …
Biocompatible Microchannel Scaffold With Microwires For Recording Regenerative Peripheral Nerve Neural Spikes, Manisankar Chennamsetti
Biocompatible Microchannel Scaffold With Microwires For Recording Regenerative Peripheral Nerve Neural Spikes, Manisankar Chennamsetti
Theses and Dissertations
A new process for the fabrication of a microchannel scaffold with microwires for peripheral nerve applications is presented. This microchannel scaffold implemented between the ends of nerves, the axons of which regenerate through microchannel in scaffold and fixed microelectrodes. This device is entirely handcrafted using commercially available materials such as microwires, PDMS film, liquid PDMS, dental cement, and epoxy glue. This device was implemented in the a Lewis rat sciatic nerve to better analyze the electrical signals of regenerated axons. 64-electrode microchannel scaffolds were developed for both peripheral nerve interfacing and peripheral nerve regeneration. The microwires were used for recording …
Microwire Regenerative Peripheral Nerve Interfaces With Wireless Recording And Stimulation Capabilities, Ali Ajam
Theses and Dissertations
A scalable microwire peripheral nerve interface was developed, which interacted with regenerated peripheral nerves in microchannel scaffolds. Neural interface technologies are envisioned to facilitate direct connections between the nervous system and external technologies such as limb prosthetics or data acquisition systems for further processing. Presented here is an animal study using a handcrafted microwire regenerative peripheral nerve interface, a novel neural interface device for communicating with peripheral nerves. The neural interface studies using animal models are crucial in the evaluation of efficacy and safety of implantable medical devices before their use in clinical studies.16-electrode microwire microchannel scaffolds were developed for …
Handcrafted Electrocorticography Electrodes For A Rodent Neural Activity, Nishat Tasnim
Handcrafted Electrocorticography Electrodes For A Rodent Neural Activity, Nishat Tasnim
Theses and Dissertations
Electrocorticography (ECoG) is a minimally invasive neural recording method that has been extensively used for neuroscience applications. Although many neural recording methods exist, ECoG provides a combination of stability, high spatial and temporal resolution with chronic and mobile capabilities. This paper presents an animal study using a low cost and simple handcrafted ECoG electrode that is made of commercially accessible materials. The study is performed on a Lewis rat implanted with a handcrafted 32-channel non-penetrative ECoG electrode covering an area of 3 x 3 mm 2 on the cortical surface. The ECoG electrodes were placed on the motor and somatosensory …
A Handcrafted Multi-Branch Nerve Scaffold For In Vivo Peripheral Nerve Regeneration, Ridwan Fayaz Hossain
A Handcrafted Multi-Branch Nerve Scaffold For In Vivo Peripheral Nerve Regeneration, Ridwan Fayaz Hossain
Theses and Dissertations
Arm and leg peripheral nerve injuries contribute largely to functional disability. These injuries seldom affect a single-line nerve; rather the injury goes beyond and disrupts the nerve tissue across multiple nerve paths. Here we investigate handcrafted PDMS based multi-branch nerve guidance conduit, which addresses this crucial branching from the sciatic nerve to aid with the regeneration to their appropriate distal targets. The design concept of the developed multiple branch nerve scaffolds is not specific for the sciatic nerve but can be modified for general use of all peripheral nerves and additional applications. Microchannels are also fabricated into a device in …