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Electrical and Computer Engineering

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Louisiana State University

2017

Cancer detection

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Surface Enhanced Raman Scattering (Sers) Substrates And Probes, Srismrita Basu Dec 2017

Surface Enhanced Raman Scattering (Sers) Substrates And Probes, Srismrita Basu

LSU Doctoral Dissertations

Raman spectroscopy is a well-known technique for complex molecular detection. In Raman spectrometry, laser beam is focused on a sample to generate a unique "fingerprint" of the molecule. The Raman signal is very weak. To overcome this problem nano rough metallic substrates are fabricated to enhance the signal strength. In clinical applications, remote contact and minimally invasive probes inside the specimen are needed.

This research work is divided in: (1) development of Surface Enhanced Raman Scattering (SERS) substrate using gold coated etched aluminum foil, (2) development of the SERS probe using the aluminum based substrate with a single optical fiber …