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Spaceflight And The Differential Gene Expression Of Human Stem Cell-Derived Cardiomyocytes, Eugenie Zhu
Spaceflight And The Differential Gene Expression Of Human Stem Cell-Derived Cardiomyocytes, Eugenie Zhu
Master's Projects
The National Aeronautics and Space Administration (NASA) has performed many experiments on the International Space Station (ISS) to further understand how conditions in space can affect life on Earth. This project analyzed GLDS-258, a gene set from NASA’s GeneLab repository which examines the impact of microgravity on human induced pluripotent stem-cell-derived cardiomyocytes (hiPSC-CMs). While many datasets have been run through NASA’s RNA-Seq Consensus Pipeline (RCP) to study differential gene expression in space, a Homo sapiens dataset has yet to be analyzed using the RCP. The aim of this project was to run the first Homo sapiens dataset, GLDS-258, through the …