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Neural Network Analysis Of Chemical Compounds In Nonrebreathing Fisher-344 Rat Breath, Robert E. Sackett Jr.
Neural Network Analysis Of Chemical Compounds In Nonrebreathing Fisher-344 Rat Breath, Robert E. Sackett Jr.
Theses and Dissertations
This research applies statistical and artificial neural network analysis to data obtained from measurement of organic compounds in the breath of a Fisher-344 rat. The Research Triangle Institute (RTI) developed a breath collection system for use with rats in order to collect and determine volatile organic compounds (VOCs) exhaled. The RTI study tested the hypothesis that VOCs, including endogenous compounds, in breath can serve as markers to exposure to various chemical compounds such as drugs, pesticides, or carcinogens normally foreign to living organisms. From a comparative analysis of chromatograms, it was concluded that the administration of carbon tetrachloride dramatically altered …