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Graduate Theses and Dissertations

Theses/Dissertations

2017

Applied sciences

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Molecular Dynamics Simulations Of Dna-Functionalized Nanoparticle Building Blocks On Gpus, Tyler Landon Fochtman May 2017

Molecular Dynamics Simulations Of Dna-Functionalized Nanoparticle Building Blocks On Gpus, Tyler Landon Fochtman

Graduate Theses and Dissertations

This thesis discusses massively parallel molecular dynamics simulations of nBLOCKs using graphical processing units. nBLOCKs are nanoscale building blocks composed of gold nanoparticles functionalized with single-stranded DNA molecules. To explore greater simulation time scales we implement our nBLOCK computational model as an extension to the coarse grain molecular simulator oxDNA. oxDNA is parameterized to match the thermodynamics of DNA strand hybridization as well as the mechanics of single stranded DNA and double stranded DNA. In addition to an in-depth review of our implementation details we also provide results of the model validation and performance tests. These validation and performance tests …


A Hybrid Partially Reconfigurable Overlay Supporting Just-In-Time Assembly Of Custom Accelerators On Fpgas, Zeyad Tariq Aklah May 2017

A Hybrid Partially Reconfigurable Overlay Supporting Just-In-Time Assembly Of Custom Accelerators On Fpgas, Zeyad Tariq Aklah

Graduate Theses and Dissertations

The state of the art in design and development flows for FPGAs are not sufficiently mature to allow programmers to implement their applications through traditional software development flows. The stipulation of synthesis as well as the requirement of background knowledge on the FPGAs' low-level physical hardware structure are major challenges that prevent programmers from using FPGAs. The reconfigurable computing community is seeking solutions to raise the level of design abstraction at which programmers must operate, and move the synthesis process out of the programmers' path through the use of overlays. A recent approach, Just-In-Time Assembly (JITA), was proposed that enables …


Exploiting Semantic Distance In Linked Open Data For Recommendation, Sultan Dawood Alfarhood May 2017

Exploiting Semantic Distance In Linked Open Data For Recommendation, Sultan Dawood Alfarhood

Graduate Theses and Dissertations

The use of Linked Open Data (LOD) has been explored in recommender systems in different ways, primarily through its graphical representation. The graph structure of LOD is utilized to measure inter-resource relatedness via their semantic distance in the graph. The intuition behind this approach is that the more connected resources are to each other, the more related they are. One drawback of this approach is that it treats all inter-resource connections identically rather than prioritizing links that may be more important in semantic relatedness calculations. Another drawback of current approaches is that they only consider resources that are connected directly …


Dpweka: Achieving Differential Privacy In Weka, Srinidhi Katla May 2017

Dpweka: Achieving Differential Privacy In Weka, Srinidhi Katla

Graduate Theses and Dissertations

Organizations belonging to the government, commercial, and non-profit industries collect and store large amounts of sensitive data, which include medical, financial, and personal information. They use data mining methods to formulate business strategies that yield high long-term and short-term financial benefits. While analyzing such data, the private information of the individuals present in the data must be protected for moral and legal reasons. Current practices such as redacting sensitive attributes, releasing only the aggregate values, and query auditing do not provide sufficient protection against an adversary armed with auxiliary information. In the presence of additional background information, the privacy protection …