Digital Commons Network^™

Cellmarkerpipe: Cell Marker Identification And Evaluation Pipeline In Single Cell Transcriptomes, Yinglu Jia, Pengchong Ma, Qiuming Yao

School of Computing: Faculty Publications

Assessing marker genes from all cell clusters can be time-consuming and lack systematic strategy. Streamlining this process through a unified computational platform that automates identification and benchmarking will greatly enhance efficiency and ensure a fair evaluation. We therefore developed a novel computational platform, cellMarkerPipe (https:// github. com/ yao- labor atory/ cellM arker Pipe), for automated cell-type specific marker gene identification from scRNA-seq data, coupled with comprehensive evaluation schema. CellMarkerPipe adaptively wraps around a collection of commonly used and state-of-the-art tools, including Seurat, COSG, SC3, SCMarker, COMET, and scGeneFit. From rigorously testing across diverse samples, we ascertain SCMarker’s overall reliable performance …

Star-Based Reachability Analysis Of Binary Neural Networks On Continuous Input, Mykhailo Ivashchenko

Department of Computer Science and Engineering: Dissertations, Theses, and Student Research

Deep Neural Networks (DNNs) have become a popular instrument for solving various real-world problems. DNNs’ sophisticated structure allows them to learn complex representations and features. However, architecture specifics and floating-point number usage result in increased computational operations complexity. For this reason, a more lightweight type of neural networks is widely used when it comes to edge devices, such as microcomputers or microcontrollers – Binary Neural Networks (BNNs). Like other DNNs, BNNs are vulnerable to adversarial attacks; even a small perturbation to the input set may lead to an errant output. Unfortunately, only a few approaches have been proposed for verifying …

A Little Loud And A Little Alone: A Phenomenology Of Leadership Identity Construction Among Women In Higher Education Technology, Amy Barry

Department of Teaching, Learning, and Teacher Education: Dissertations, Theses, and Student Research

This qualitative study is an exploration of how women in higher education information technology (IT) positions navigate constructing their leadership identities. This includes the messy, personal, internal identity work that occurs prior to claiming their leadership identities on the public stage, followed by an examination of what the experience of attempting to claim and negotiate a leadership identity is like in the social context of their organizations. This educational and sociological study employs an Interpretative Phenomenological Analysis approach with a series of three interviews per participant that allowed the researcher to deeply explore the personal identity experiences of participants. Findings …

Sliding Markov Decision Processes For Dynamic Task Planning On Uncrewed Aerial Vehicles, Trent Wiens

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Mission and flight planning problems for uncrewed aircraft systems (UASs) are typically large and complex in space and computational requirements. With enough time and computing resources, some of these problems may be solvable offline and then executed during flight. In dynamic or uncertain environments, however, the mission may require online adaptation and replanning. In this work, we will discuss methods of creating MDPs for online applications, and a method of using a sliding resolution and receding horizon approach to build and solve Markov Decision Processes (MDPs) in practical planing applications for UASs. In this strategy, called a Sliding Markov Decision …

Vr Circuit Simulation With Advanced Visualization For Enhancing Comprehension In Electrical Engineering, Elliott Wolbach

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

As technology advances, the field of electrical and computer engineering continuously demands innovative tools and methodologies to facilitate effective learning and comprehension of fundamental concepts. Through a comprehensive literature review, it was discovered that there was a gap in the current research on using VR technology to effectively visualize and comprehend non-observable electrical characteristics of electronic circuits. This thesis explores the integration of Virtual Reality (VR) technology and real-time electronic circuit simulation with enhanced visualization of non-observable concepts such as voltage distribution and current flow within these circuits. The primary objective is to develop an immersive educational platform that makes …

Next-Generation Crop Monitoring Technologies: Case Studies About Edge Image Processing For Crop Monitoring And Soil Water Property Modeling Via Above-Ground Sensors, Nipuna Chamara

Dissertations and Doctoral Documents from University of Nebraska-Lincoln, 2023–

Artificial Intelligence (AI) has advanced rapidly in the past two decades. Internet of Things (IoT) technology has advanced rapidly during the last decade. Merging these two technologies has immense potential in several industries, including agriculture.

We have identified several research gaps in utilizing IoT technology in agriculture. One problem was the digital divide between rural, unconnected, or limited connected areas and urban areas for utilizing images for decision-making, which has advanced with the growth of AI. Another area for improvement was the farmers' demotivation to use in-situ soil moisture sensors for irrigation decision-making due to inherited installation difficulties. As Nebraska …

Asteroidal Sets And Dominating Targets In Graphs, Oleksiy Al-Saadi

Department of Computer Science and Engineering: Dissertations, Theses, and Student Research

The focus of this PhD thesis is on various distance and domination properties in graphs. In particular, we prove strong results about the interactions between asteroidal sets and dominating targets. Our results add to or extend a plethora of results on these properties within the literature. We define the class of strict dominating pair graphs and show structural and algorithmic properties of this class. Notably, we prove that such graphs have diameter 3, 4, or contain an asteroidal quadruple. Then, we design an algorithm to to efficiently recognize chordal hereditary dominating pair graphs. We provide new results that describe the …

The Osteobiography Of Human Remains From The Seaview And Indian Town Trail Archaeological Sites, Annissa Davis

Anthropology Department: Theses

This thesis examines the use of 3D modeling in museum exhibition to create exploratory exhibits that facilitate unique relationships between the visitors and the collection beyond what is provided by the collection’s in person counterparts. Typical use of 3D modeling in museums is currently often representative rather than exploratory. By employing a Digital Humanities lens to approach the development of a digital exhibition utilizing 3D technology and interactive elements created in a video game engine (Unity), this thesis project evaluates these potential new relationships. Using the Eloise Kruger Collection of Miniatures as a case study, the following text details the …

Micrornas In Pancreatic Cancer: Advances In Biomarker Discovery And Therapeutic Implications, Roland Madadjim, Thuy An, Juan Cui

School of Computing: Faculty Publications

Pancreatic cancer remains a formidable malignancy characterized by high mortality rates, primarily attributable to late-stage diagnosis and a dearth of effective therapeutic interventions. The identification of reliable biomarkers holds paramount importance in enhancing early detection, prognostic evaluation, and targeted treatment modalities. Small non-coding RNAs, particularly microRNAs, have emerged as promising candidates for pancreatic cancer biomarkers in recent years. In this review, we delve into the evolving role of cellular and circulating miRNAs, including exosomal miRNAs, in the diagnosis, prognosis, and therapeutic targeting of pancreatic cancer. Drawing upon the latest research advancements in omics data-driven biomarker discovery, we also perform a …