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Comparison Of Methods Used For Aligning Protein Sequences, Sangeetha Madangopal

Computer Science Theses

Comparing protein sequences is an essential procedure that has many applications in the field of bioinformatics. The recent advances in computational capabilities and algorithm design, simplified the comparison procedure of protein sequences from several databases. Various algorithms have emerged using state of the art approaches to match protein sequences based on structural and functional properties of the amino acids. The matching involves structural alignment, and this alignment may be global; comprising of the whole length of the protein, or local; comprising of the sub-sequences of the proteins. Families of related proteins are found by clustering sequence alignments. The frequency distributions …