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Topological Biclustering Artmap, Raghu Yelugam
Topological Biclustering Artmap, Raghu Yelugam
Masters Theses
”Detection of gene mutations is central for assessing genetic factors affecting disease predisposition, genetic causes of a particular disease, and gene-targeted treatment. DNA microarray methods are widely used to detect mutations by contrasting the expression levels of thousands of genes together under varying experimental conditions. The experimental conditions could be diseased cell states compared with the normal cell states. Biclustering, a robust exploratory data analysis tool, can be applied to microarray data to detect subsets of genes that co-express highly only for a subset of experimental conditions. Such detection is crucial for gaining insights into gene regulatory networks, differential gene …
Neural Network Supervised And Reinforcement Learning For Neurological, Diagnostic, And Modeling Problems, Donald Wunsch Iii
Neural Network Supervised And Reinforcement Learning For Neurological, Diagnostic, And Modeling Problems, Donald Wunsch Iii
Masters Theses
“As the medical world becomes increasingly intertwined with the tech sphere, machine learning on medical datasets and mathematical models becomes an attractive application. This research looks at the predictive capabilities of neural networks and other machine learning algorithms, and assesses the validity of several feature selection strategies to reduce the negative effects of high dataset dimensionality. Our results indicate that several feature selection methods can maintain high validation and test accuracy on classification tasks, with neural networks performing best, for both single class and multi-class classification applications. This research also evaluates a proof-of-concept application of a deep-Q-learning network (DQN) to …