Digital Commons Network^™

The P600 Event-Related Potential Across Ages And Ear Conditions, Kyla Lewis Tree

Theses and Dissertations

Studying language development through event-related potentials provides specific information regarding how the brain processes specific aspects of language over time. In this study, the P600 component, a positive wave occurring approximately 600 ms post-stimulus and known for detecting syntactic errors, was specifically analyzed. Thirty children between the ages of 5 and 12 years listened to linguistically correct, syntactically incorrect, and semantically incorrect sentences in three ear conditions: monaurally to the right ear, monaurally to the left ear, and binaurally. The participants were instructed to judge the sentences to be correct or incorrect. Comparisons were then made of the latency and …

Structural Characterization Of The C-Terminus Of The Cochlear Motor Protein Prestin: Intrinsic Disorder Linked To Voltage Sensor Function, Michael S. Podgorski

Theses and Dissertations (ETD)

The sensitivity of mammalian hearing relies upon the ability to amplify sound. Outer hair cells (OHCs) in the cochlea have motile properties that support this function. The motor protein called prestin resides in the lateral wall of the OHCs. Prestin undergoes voltage-dependent conformational changes, which correlates to the movement of charge through the membrane or non-linear capacitance (NLC). This property underlies OHC electromotility. A mechanistic understanding of prestin’s function remains unknown. Previous research has tied prestin’s C-terminus (residues 499-799) to the voltage-dependent events that occur in the membrane. The folding and biochemical properties of prestin’s C-terminus were characterized. This information …

Chronic Subjective Dizziness (Csd) Vs. Conversion Disorder: Discussion Of Clinical Findings And Rehabilitation., Julie A. Honaker, Jane M. Gilbert, Jeffrey P. Staab

Department of Special Education and Communication Disorders: Faculty Publications

PURPOSE: Audiologists frequently encounter patients who complain of chronic dizziness or imbalance, in the absence of active vestibular or neurological deficits. Knowledge about conditions that cause this clinical presentation will allow audiologists to make important contributions to accurate diagnosis and effective management of these patients. This article reviews two such conditions, chronic subjective dizziness (CSD) and conversion disorder. METHOD: A case of CSD and another of conversion disorder are presented with a literature review of their clinical presentations, key diagnostic features, and treatment strategies. The role of the audiologist in assessing patients with these conditions and facilitating appropriate treatment referrals …

Modified Head Shake Computerized Dynamic Posturography, Julie A. Honaker, Connie M. Converse, Neil T. Shepard

Department of Special Education and Communication Disorders: Faculty Publications

PURPOSE: Recent research on head shake posturography has demonstrated a modest increase in sensitivity to identifying peripheral vestibular system asymmetry when horizontal head movements were added to portions of the standard Sensory Organization Test (SOT) battery. However, limitations with respect to the head shake protocol were outlined, and usable data for assessing performance could not be established. The purpose of this study was to test a change in protocol for use of head shake SOT to address the noted limitations.
METHOD: Forty participants ranging in age from 20 to 79 years with no history of dizziness completed Conditions 2 and …

Talk To Me: Issues In Acquiring Spoken Language For Young Children With Autism Spectrum Disorders, Rhea Paul

Communication Disorders Faculty Publications

Speech-language pathologists play a critical role in the treatment of children with autism spectrum disorders (ASD) because communication deficits are a primary component of both the diagnostic criteria and the focus of educational services for children with these conditions. Children with ASD almost always are delayed in speech acquisition (Tager-Flusberg, Paul, & Lord, 2005), as well as in other areas of communication. Lack of speech is often the most obvious symptom and greatest cause for concern of parents of toddlers who are eventually diagnosed with ASD, even though closer observation usually reveals additional problems.

Barriers Influencing Minority Clients’ Access To Speech Language Pathology Services. Poster, Nidhi Mahendra, Katie Schoneman, Nisha Engineer

Faculty Publications

No abstract provided.

Computer-Based Cognitive Interventions For Persons With Dementia: Feasibility And Outcomes, Nidhi Mahendra, Allegra Apple, Susan Carroll, Adithya Chandregowda

Faculty Publications

No abstract provided.

Temporal Order Processing Of Syllables In The Left Parietal Lobe, Dana C. Moser, Julie M. Baker, Carmen E. Sanchez, Chris Rorden, Julius Fridriksson

Communication Sciences & Disorders

Speech processing requires the temporal parsing of syllable order. Individuals suffering from posterior left hemisphere brain injury often exhibit temporal processing deficits as well as language deficits. Although the right posterior inferior parietal lobe has been implicated in temporal order judgments (TOJs) of visual information, there is limited evidence to support the role of the left inferior parietal lobe (IPL) in processing syllable order. The purpose of this study was to examine whether the left inferior parietal lobe is recruited during temporal order judgments of speech stimuli. Functional magnetic resonance imaging data were collected on 14 normal participants while they …

Effects Of External Noise On Detection Of Intensity Increments, Walt Jesteadt, Kim Schairer, Lance Nizami, Samar Khaddam, Stephen T. Neely

Kim S. Schairer

Acoustic And Spectral Patterns In Young Children's Stop Consonant Productions, Shawn L. Nissen, Robert Allen Fox

Faculty Publications

The aim of this study was to examine the acoustic and spectral patterns of stop articulation in the speech of pre-pubescent children. A set of voiceless stop consonants, /ptk/, produced by a group of adults and typically developing children 3-5 years of age were examined in terms of multiple acoustic and spectral parameters. Findings indicated that, with the exception of spectral kurtosis, the acoustic and spectral characteristics of the stop productions varied significantly as a function of place of articulation and vowel context. Sex-specific differences in spectral slope, mean, and skewness were found for the 5-year-old and adult speakers. Such …

Modulations Of Cell Cycle Checkpoints During Hcv Associated Disease, Anwar Ali Siddiqui, Saira Sarfraz, Wasim Jafri, Saeed Hamid, Syed Ali

Department of Biological & Biomedical Sciences

Background

Impaired proliferation of hepatocytes has been reported in chronic Hepatitis C virus infection. Considering the fundamental role played by cell cycle proteins in controlling cell proliferation, altered regulation of these proteins could significantly contribute to HCV disease progression and subsequent hepatocellular carcinoma (HCC). This study aimed to identify the alterations in cell cycle genes expression with respect to early and advanced disease of chronic HCV infection.

Methods

Using freshly frozen liver biopsies, mRNA levels of 84 cell cycle genes in pooled RNA samples from patients with early or advanced fibrosis of chronic HCV infection were studied. To associate mRNA …

Automated Identification Of Noun Clauses In Clinical Language Samples, Britney Richey Manning

Theses and Dissertations

The identification of complex grammatical structures including noun clauses is of clinical importance because differences in the use of these structures have been found between individuals with and without language impairment. In recent years, computer software has been used to assist in analyzing clinical language samples. However, this software has been unable to accurately identify complex syntactic structures such as noun clauses. The present study investigated the accuracy of new software, called Cx, in identifying finite wh- and that-noun clauses. Two sets of language samples were used. One set included 10 children with language impairment, 10 age-matched peers, …

Development Of Psychometrically Equivalent Speech Audiometry Materials For Testing Children In Mongolian, Meghan Elizabeth Caldwell

Theses and Dissertations

The purpose of this study was to develop, digitally record, evaluate, and equate Mongolian monosyllabic and bisyllabic child-appropriate words which can be used in the measurement of word recognition scores and speech-reception threshold (SRT) in children who are native speakers of Mongolian. Based on data collected from a survey of Mongolian child language professionals, a subset of child-appropriate materials was adapted from a set of materials developed for Mongolian adults. Two lists of 50 monosyllabic words and four half-lists of 25 words each were developed for testing the word recognition abilities of Mongolian children. The developed lists and half-lists were …

Patterns Of Vowel Production In Speakers Of American English From The State Of Utah, Larkin Hopkins Reeves

Theses and Dissertations

The English spoken in the United States has traditionally been divided into six dialect regions: New England, Mid-Atlantic, Southern, Midland, Northern, and Western. The acoustic properties of American English spoken in the Southern and Northern dialect regions have been the subject of intense research, but the acoustic properties of the Western dialect region have not been analyzed as thoroughly. The umbrella term, Western American English, includes the English spoken in a large geographic area that stretches from Montana, Wyoming, Colorado, and New Mexico to the Pacific coast. Research that has focused on the Western dialect has included participants from several …

The Withdrawn And Sociable Behaviors Of Children With Specific And Nonspecific Language Impairment, Heather Haskin

Theses and Dissertations

Recently researchers have identified a group of children with language impairment (LI) whose IQ scores are below the typical IQ cutoff of 85 for specific language impairment (SLI) but above the IQ cutoff of 70 for intellectual disability (Weismer et al., 2000). This group is referred to as having nonspecific language impairment (NLI). Eleven children with NLI, eleven same-age peers with SLI, and eleven same-age typical peers were compared on withdrawn and sociable behaviors demonstrated in the classroom setting using the Teacher Behavior Rating Scale (Hart & Robinson, 1996). Three subtypes of withdrawal (solitary-active, solitary-passive, reticent) and two subtypes of …

Phonological Accuracy And Intelligibility In Connected Speech Of Boys With Fragile X Syndrome Or Down Syndrome, Elizabeth Barnes, Joanne Roberts, Steven Long, Gary E. Martin, Mary C. Berni, Kerry C. Mandulak, John Sideris

Speech Pathology and Audiology Faculty Research and Publications

Purpose: To compare the phonological accuracy and speech intelligibility of boys with fragile X syndrome with autism spectrum disorder (FXS-ASD), fragile X syndrome only (FXS-O), Down syndrome (DS), and typically developing (TD) boys.

Method: Participants were 32 boys with FXS-O (3–14 years), 31 with FXS-ASD (5–15 years), 34 with DS (4–16 years), and 45 TD boys of similar nonverbal mental age. We used connected speech samples to compute measures of phonological accuracy, phonological process occurrence, and intelligibility.

Results: The boys with FXS, regardless of autism status, did not differ from TD boys on phonological accuracy and phonological …

Improving The Quality Of Early Hearing Detection And Intervention Services Through Physician Outreach, Karen F. Muñoz, L. Shisler, M. Moeller, K. White

Communicative Disorders and Deaf Education Faculty Publications

Physicians and other health-care providers should play a central role in helping families of children with permanent hearing loss receive timely and appropriate screening, diagnostic, and early intervention services. Because the technology and procedures for ensuring timely and appropriate services for infants and young children with hearing loss have changed so dramatically over the past 15 years, many health-care providers are not well informed about the best ways to provide effective services. Audiologists can help to ensure that physicians and other health-care providers are better informed about the services needed by infants and young children with hearing loss. This article …

The Assessment And Treatment Of Prosodic Disorders And Neurological Theories Of Prosody, Joshua J. Diehl, Rhea Paul

Communication Disorders Faculty Publications

In this article, we comment on specific aspects of Peppe´ (Peppe´ , 2009). In particular, we address the assessment and treatment of prosody in clinical settings and discuss current theory on neurological models of prosody. We argue that in order for prosodic assessment instruments and treatment programs to be clinical effective, we need assessment instruments that: (1) have a representative normative comparison sample and strong psychometric properties; (2) are based on empirical information regarding the typical sequence of prosodic acquisition and are sensitive to developmental change; (3) meaningfully subcategorize various aspects of prosody; (4) use tasks that have ecological validity; …

Velopharyngeal Insufficiency: Diagnosis And Management, Robert J. Shprintzen, Eileen Marrinan

Communication Disorders Faculty Publications

Journal articles relevant to the diagnosis and treatment of velopharyngeal insufficiency were reviewed. All studies ascertained by PubMed search were included. Recent findings: Studies reported on the application of magnetic resonance scanning, reliability tests of the International Working Group diagnostic protocol, the use of nasometry, and techniques designed to assess the function of the velopharyngeal mechanism. Treatment studies focused on outcomes in small samples of cases and complication rates from pharyngeal flap. One study discussed ineffective speech therapy procedures. Summary: There were relatively few studies this past year. Those that were published were hindered by small and heterogeneous sample sizes …

Syntactic Complexity In Persons With Multiple Sclerosis, Katherine A. King

Theses and Dissertations

Several studies using standardized tests have provided evidence for the presence of language disorders in persons with Multiple Sclerosis (MS) and have suggested that persons with MS may have language that is less complex. One aspect not thoroughly studied is that of syntactic complexity in naturalistic, conversational settings. The present study collected language samples from 10 adults with MS and 10 age-matched controls and compared scores on five quantitative measures derived from those samples. No significant differences were found between groups on any measure. This finding suggests that in mild cases of MS or during periods of remission, individuals may …

The Variability In Children With Specific Language Impairment Compared To Children With Typical Language Development, Heather Michelle Wilde

Theses and Dissertations

The purpose of this study was to determine whether children with specific language impairment (SLI) are more or less variable than children with typically developing language. In addition, the within child variability for children with SLI was analyzed to consider how heterogeneity influenced identification of areas of linguistic strengths and weaknesses in this population. Fifty seven children with SLI, 7:0–11:0, and fifty seven of their peers with typically developing language were assessed using five subtests and a composite language score from the Comprehensive Assessment of Spoken Language (CASL) (Carrow-Woolfolk, 1999). The children with typically developing language were significantly more variable …

A Perceptual Evaluation Of The Effect Of A Pseudopalate On Voiceless Obstruent Production And Motor Adaptation, Megan Ann Cannon Williams

Theses and Dissertations

Electropalatography (EPG) has proven to be a useful clinical and research tool for measuring tongue-to-palate contact. Research has shown sensorimotor adaptation to an EPG device may be possible following a short period of speech practice. This study was developed in order to better understand how a listeners' perception of speech clarity is effected by the presence of a relatively thin artificial pseudopalate in the speakers' oral cavity. Twenty listeners rated 220 speech stimuli on a visual analog scale ranging from normal to very distorted speech clarity. The stimuli included two different American English sentences. Speech clarity ratings were looked at …

The Effects Of Intensive Lower Limb Training On The Speech Of Patients With Parkinson's Disease, Lauren Fjeldsted Allen

Theses and Dissertations

Research has documented the positive effects of physical therapy as a treatment for limb motor symptoms associated with Parkinson's disease (PD). Previous studies have shown that speech and voice measures can be reflective of overall cardiovascular health and fitness in young, middle-aged, and older adults. In healthy individuals, increased respiratory drive has been found to influence vocal function and speech articulation. The rationale for the present study was that improved lower limb function might lead to improvements in overall fitness, which then may influence speech in individuals with Parkinson's disease. To investigate this premise, 10 participants diagnosed with mild to …

Finish-A-Rhyme-Story: A Rhyme Cloze Assessment For Preschool Children, Kimberly Jeanne Condie

Theses and Dissertations

Educators need measurement tools to determine phonological awareness in young children. This study investigated the appropriateness of rhyme cloze tasks, referred to as Finish-a-Rhyme-Story items, which were designed to measure preschool and kindergarten children's early rhyme development. The rhyme cloze tasks required children to verbally complete a sentence by filling in a final rhyming word that matched a rhyme pattern highlighted in a short story that was read aloud to them. The task required rhyme awareness as well as comprehension of the language in the story. Twenty-four items were individually administered to preschool (n = 207) and kindergarten (n = …

The Effect Of Fatigue On Acoustic Measures Of Diphthongs In Individuals With Multiple Sclerosis, Kristi Lee Hollis

Theses and Dissertations

Although recent literature suggests that fatigue influences the communication of people with multiple sclerosis (MS), its relationship to acoustic measures of speech, specifically formant transitions during diphthongs, has not been explored. In the present study, 11 participants diagnosed with MS, two of whom were perceptually dysarthric, and 12 control subjects were recorded as they performed selected speech tasks in both the morning and the afternoon. Before each recording session, participants rated their fatigue level. The participants with MS gave significantly higher ratings of fatigue than the control group. The speakers with MS had longer diphthong durations in a non-fatigued state, …

Validity Of Seven Syntactic Analyses Performed By The Computerized Profiling Software, Stacy Lynn Minch

Theses and Dissertations

The Computerized Profiling (CP) software extracts several quantitative measures from a transcribed sample of a client's language. These analyses include the Mean Length of Utterance in Words (MLU-W) and in Morphemes (MLU-M), the Mean Syntactic Length (MSL), the Syntactic Complexity Score (SCS), Developmental Sentence Scoring (DSS), the Index of Productive Syntax (IPSyn), and the Picture-Elicited Screening Procedure for LARSP (PSL). The validity of these measures was examined by comparing them to the number of finite nominal, adverbial, and relative clauses contained in samples from 54 first-, 48 third-, and 48 fifth-grade students and 24 young adults. The DSS and SCS …

Psychometrically Equivalent Monosyllabic Words For Word Recognition Testing In Mongolian., Valarie Nicole Haslam

Theses and Dissertations

The purpose of this study was to record a set of Mongolian monosyllabic word lists that could be used to obtain a word recognition score. A word list was developed of 190 frequently used monosyllabic words which had been selected by a group of raters. Native male and female Mongolian talkers were utilized to make digital recordings. The 190 words were divided into 10 lists of 19 words. The lists were presented to 20 normally hearing subjects at 10 different intensity levels ranging from -5 to 40 dB HL in 5 dB increments. An S-curve distribution was used to divide …

Phonemic Categorization Of Eight-To-Ten Year Old Children With An Articulation Disorder, Marjorie A. Smith

Theses and Dissertations

Phonemic categorization is the ability to discriminate and organize speech sounds into categories. This ability begins soon after birth and continues to refine as an individual matures. An association between categorical labeling and phonological awareness has been reported. A strong link between perception and production has been established. The present study examined phonemic categorization of two groups of four listeners. Eight-to ten-year-old children with an articulation disorder were compared with typically speaking peers to determine if the two groups differed in their ability to categorize speech sounds. Behavioral and electrophysiological measures were used to ascertain if any differences existed. These …

A Comparison Of Seven Automated Measures Of Syntactic Complexity, Laura Elizabeth Wilde

Theses and Dissertations

This study compared seven syntactic measures which can be automatically generated by the Computerized Profiling (CP) software: Mean Length of Utterance in morphemes or words (MLUm or MLUw), Mean Syntactic Length (MSL), the Index of Productive Syntax (IPSyn), the Picture Elicited Scoring Procedure (PESP) for the Language Analysis Remediation and Screening Profile (LARSP), the Syntactic Complexity Score (MSC) scoring of LARSP, and Developmental Sentence Scoring (DSS). Language samples came from 192 children, 106 typically developing children, ages 5;6 to 11;2 and 86 children with language impairment, ages 5;6 to 11;1. Patterns of correlation were consistent for children with or without …

Defining Spoken Language Benchmarks And Selecting Measures Of Expressive Language Development For Young Children With Autism Spectrum Disorders, Helen Tager-Flusberg, Sally Rogers, Judith Cooper, Rebecca Landa, Catherine Lord, Rhea Paul, Mabel Rice, Carol Stoel-Gammon, Amy Wetherby, Paul Yoder

Communication Disorders Faculty Publications

Purpose: The aims of this article are twofold: (a) to offer a set of recommended measures that can be used for evaluating the efficacy of interventions that target spoken language acquisition as part of treatment research studies or for use in applied settings and (b) to propose and define a common terminology for describing levels of spoken language ability in the expressive modality and to set benchmarks for determining a child's language level in order to establish a framework for comparing outcomes across intervention studies.
Method: The National Institute on Deafness and Other Communication Disorders assembled a group of researchers …