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Verbal Fluency In Women With The Fmr1 Premutation And The Broad Autism Phenotype, Emily Szabo
Verbal Fluency In Women With The Fmr1 Premutation And The Broad Autism Phenotype, Emily Szabo
Theses and Dissertations
Women who carry a premutation allele on the FMR1 gene can experience limitations due to their genetic status, including executive function deficits. These subtle deficits are often shared by women who possess the broad autism phenotype (BAP). Poor understanding and limited research on the extent of these executive functioning deficits has led to limited clinical management of these two groups. The current study aimed to clarity whether there is a difference in verbal fluency abilities in mothers that possess the FMR1 premutation, mothers of children with autism who are at risk for the BAP, and mothers of typically developing children, …
Antisaccade Performance As A Measure Of Executive Dysfunction In Women With The Fmr1 Premutation, Lyndsay Schmitt
Antisaccade Performance As A Measure Of Executive Dysfunction In Women With The Fmr1 Premutation, Lyndsay Schmitt
Theses and Dissertations
Women with the FMR1 premutation appear to be at increased risk for executive dysfunction. Findings in this regard have been mixed, leading to controversy surrounding the executive phenotype. Inhibitory deficits have been a more consistently documented component of this cognitive profile (Klusek et al., 2020; Shelton et al., 2014). This study aimed to clarify the executive phenotype through use of the antisaccade task, a well referenced eye-tracking paradigm that targets oculomotor inhibition and motor control and imposes time constraints that may increase sensitivity to executive deficits in women with the FMR1 premutation. The effects of aging were examined in both …