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Ruthenium Catalyzed Deaminative Coupling Reaction Of Amines Via C-N Bond Activation, Pandula T. Kirinde Arachchige

Master's Theses (2009 -)

C–N bond activation via transition-metal catalyst has attracted much attention during the past two decades. This strategy has become one of the most promising way to generate secondary amines, which are very important in a broad spectrum of applications in pharmaceutical industry, synthetic organic chemistry and material science. The secondary amines can be utilized as an important synthetic intermediate for further manipulations. The in-situ formed catalytic system generated from the tetranuclear Ru–H complex with 4-(1,1-dimethylethyl)-1,2-benzenediol ligand was found to be effective for the synthesis of secondary amines from the direct deaminative coupling of amines. The ruthenium catalyst was highly effective …