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Study Of Polychlorinated Biphenyl Dechlorination By Zero Valent Magnesium With And Without Activated Carbon In Acidified Ethanol-Ethyl Lactate System, Fiona Zullo
Electronic Theses and Dissertations
Polychlorinated biphenyls (PCBs) are synthetic organic chemicals that ca de detected in the environment worldwide. PCBs were banned in the U.S in 1979 owing to their toxicity and persistence in the environment. Today PCBs are classified as human carcinogens and are among the top ten of the U.S Environmental Protection Agency's (EPA) most toxic chemicals. Many researchers have shown soil to be contaminated with PCBs at concentrations as high as 750 ppm. Given the toxicity of PCBs, there is an urgent need to extract and degrade such chemicals from contaminated soil in a cost effective way. Prior work revealed a …
Novel Photodynamic Cancer Therapy Agent And Biochemical Phosphate Sensor Based On Nanomaterials, Alaa Fadhel
Novel Photodynamic Cancer Therapy Agent And Biochemical Phosphate Sensor Based On Nanomaterials, Alaa Fadhel
Electronic Theses and Dissertations
Biochemical research and clinical studies have revolutionized the field of medicine in both diagnosis and therapy. Researchers in the field of biochemistry and biotechnology are using nanomaterials in different applications to develop devices and materials that offer benefits to both patients and the health care industry. These include biochemical sensors, enzyme encapsulation, biomarkers, and drug delivery improvements for the treatment of cancer. This dissertation focuses on investigating two biochemical aspects using nanomaterials; namely therapy and clinical diagnosis. For therapy purposes, Silica nanoparticles were used as drug delivery system to develop a new photodynamic cancer therapy agent photo-acid generator (PAG) that …
Analysis Of Benzopyrenes And Benzopyrene Metabolites By Fluorescence Spectroscopy Techniques, Bassam Al-Farhani
Analysis Of Benzopyrenes And Benzopyrene Metabolites By Fluorescence Spectroscopy Techniques, Bassam Al-Farhani
Electronic Theses and Dissertations
Polycyclic aromatic hydrocarbons (PAHs) are some of the most common and toxic pollutants encountered worldwide. Presently, monitoring is restricted to sixteen PAHs, but it is well understood that this list omits many toxic PAHs. Among the "forgotten" PAHs, isomers with molecular weight 302 are of particular concern due to their high toxicological properties. The chromatographic analysis of PAHs with MW 302 is challenged by similar retention times and virtually identical mass fragmentation patterns. The first original component of this dissertation evolves from a high-resolution spectroscopic approach specifically developed to fulfil this gap. Herein, 4.2 K Laser-Excited Time-Resolved Shpol'skii Spectroscopy (4.2K …
The Owl Sensor: A Smart Nanostructure For Single Nucleotide Variation Analysis, Rebekah Karadeema
The Owl Sensor: A Smart Nanostructure For Single Nucleotide Variation Analysis, Rebekah Karadeema
Electronic Theses and Dissertations
Analysis of single nucleotide variations (SNVs) in DNA and RNA sequences is extensively used in healthcare for detection of genetic mutations and analysis of drug resistant pathogens. Here we developed a nucleic acid sensor able to differentiate between a fully matched analyte and one with a SNV in a wide temperature range of 5°C-32°C. The sensor, dubbed here the 'Owl Sensor' due to the complex's resemblance to owl eyes, utilizes recent developments in DNA nanotechnology and synthetic biology to self-assemble a fluorescent DNA nanostructure called a Double Crossover, or DX Tile, capable of differentiating SNVs in a large temperature range, …
Multidimensional Room-Temperature Fluorescence Microscopy For The Nondestructive Analysis Of Forensic Trace Textile Fibers, Nirvani Mujumdar
Multidimensional Room-Temperature Fluorescence Microscopy For The Nondestructive Analysis Of Forensic Trace Textile Fibers, Nirvani Mujumdar
Electronic Theses and Dissertations
The purpose of this dissertation is to advance nondestructive methodology for forensic fiber examination. Non-destructive techniques that can either discriminate between similar fibers or match a known to a questioned fiber – and still preserve the physical integrity of the fibers for further court examination - are highly valuable in forensic science. A challenging aspect of forensic fiber examinations involves the comparison of fibers colored with visually indistinguishable dyestuffs. This is not an uncommon situation, as there are numerous indistinguishable fibers pre-dyed with commercial dyes of virtually identical colors. Minimal chemical structural variations are actually encouraged by the dye patent …
Theoretical-Experimental Study Of The Two-Photon Circular Dichroism Of Helicenes And Aromatic Amino Acids In The Uv Region: From The Structure-Property Relationship To The Final Implementation, Yuly Katherine Vesga Prada
Theoretical-Experimental Study Of The Two-Photon Circular Dichroism Of Helicenes And Aromatic Amino Acids In The Uv Region: From The Structure-Property Relationship To The Final Implementation, Yuly Katherine Vesga Prada
Electronic Theses and Dissertations
Two-photon circular dichroism (TPCD) has been recognized for its exceptional spectroscopic ability for the structural and conformational analysis of chiral systems due to its high sensitivity to small peptide structural distortions. In 2008, Hernandez and co-workers demonstrated TPCD experimentally by the development of the Double L-scan technique. Since then, we have been working on a systematic theoretical-experimental study of chiral molecules using TPCD. In this dissertation, I present my contribution to the continuation to the study of the structure-property relationship of TPCD in molecules with axial chirality in solution, as well as the implementation of the TPCD measurements in the …
Plasma Temperature Measurements In The Context Of Spectral Interference, Brandon Seesahai
Plasma Temperature Measurements In The Context Of Spectral Interference, Brandon Seesahai
Honors Undergraduate Theses
The path explored in this thesis is testing a plasma temperature measurement approach that accounts for interference in a spectrum. The Atomic Emission Spectroscopy (AES) technique used is called Laser Induced Breakdown Spectroscopy (LIBS) and involves focusing a laser pulse to a high irradiance onto a sample to induced a plasma. Spectrally analyzing the plasma light provides a "finger print" or spectrum of the sample. Unfortunately, spectral line broadening is a type of interference encountered in a LIBS spectrum because it blends possible ionic or atomic transitions that occur in plasma. To make use of the information or transitions not …
Degradation Of Hexachlorobenzene, Pentachlorophenol And Pentachloroanisole Using Activated Magnesium In An Acidified Ethanol/Ethyl Lactate Cosolvent System, Amel Garbou
Electronic Theses and Dissertations
For many centuries, chemists have dedicated many labor-intensive hours to improving the quality of life for mankind by developing synthetic methods for the production of compounds which fulfill the needs and meet the demands of society. However, the innovation of such compounds has frequently come at the cost of detrimental side-effects that do not always present themselves until many years, or even decades, following their initial application. Many compounds in this category come in the form of globally-distributed halogenated molecules which are toxic to many living organisms, susceptible to bioaccumulation and resistant to biodegradation processes. Such compounds are classified as …