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Effects Of Internals Configurations On Heat Transfer And Hydrodynamics In Bubble Columns - With And Without Solid Particles, Anil Kumar Jhawar

Electronic Thesis and Dissertation Repository

Internals of different types are required in a number of industrial applications of bubble columns to achieve the desired mixing or to remove the heat of reaction to maintain desired temperature and isothermal conditions of operation. Some of these applications include Fischer-Tropsch synthesis, methanol synthesis, and production of dimethyl ether (DME). The presence of internals however can alter the column hydrodynamics and mixing patterns which could influence reactor performance. A fast response probe capable of capturing bubble dynamics, as well as detecting flow direction is used to study the effect of internals on local heat transfer and column hydrodynamics in …

Effects Of Operating And Geometric Variables On Hydrodynamics And Tablet Dissolution In Standard And Modified Dissolution Testing Apparatuses 2, Yimin Wang

Dissertations

Dissolution testing is routinely conducted in the pharmaceutical industry to provide critical in vitro drug release information for quality control purposes, and especially to assess batch-to-batch consistency of solid oral dosage forms such as tablets. Among the different types of apparatuses listed in the United States Pharmacopoeia (USP), the most commonly used dissolution system for solid dosage forms is the USP Dissolution Testing Apparatus 2, consisting of an unbaffled, hemispherical-bottomed vessel equipped with a 2-blade radial impeller.

Despite its extensive use in industry and a large body of work, some key aspects of the hydrodynamics of Apparatus 2 have received …