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Matrix Effects On Interdiffusion At The Polystyrene And Poly(Vinyl Methyl Ether) Interface, Esmaiel Jabbari, Nikolaos Peppas
Matrix Effects On Interdiffusion At The Polystyrene And Poly(Vinyl Methyl Ether) Interface, Esmaiel Jabbari, Nikolaos Peppas
Esmaiel Jabbari
No abstract provided.
Thermally Cross-Linked Oligo(Poly(Ethylene Glycol) Fumarate) Hydrogels Support Osteogenic Differentiation Of Encapsulated Marrow Stromal Cells In Vitro, Johnna Temenoff, Hansoo Park, Esmaiel Jabbari, Daniel Conway, Tiffany Sheffield, Catherine Ambrose, Antonios Mikos
Thermally Cross-Linked Oligo(Poly(Ethylene Glycol) Fumarate) Hydrogels Support Osteogenic Differentiation Of Encapsulated Marrow Stromal Cells In Vitro, Johnna Temenoff, Hansoo Park, Esmaiel Jabbari, Daniel Conway, Tiffany Sheffield, Catherine Ambrose, Antonios Mikos
Esmaiel Jabbari
No abstract provided.
Three-Dimensional Engineered Matrix To Study Cancer Stem Cells And Tumorsphere Formation: Effect Of Matrix Modulus, Xiaoming Yang, Samaneh Sarvestani, Seyedsina Moeinzadeh, Xuezhong He, Esmaiel Jabbari
Three-Dimensional Engineered Matrix To Study Cancer Stem Cells And Tumorsphere Formation: Effect Of Matrix Modulus, Xiaoming Yang, Samaneh Sarvestani, Seyedsina Moeinzadeh, Xuezhong He, Esmaiel Jabbari
Esmaiel Jabbari
Maintenance of cancer stem cells (CSCs) is regulated by the tumor microenvironment. Synthetic hydrogels provide the flexibility to design three-dimensional (3D) matrices to isolate and study individual factors in the tumor microenvironment. The objective of this work was to investigate the effect of matrix modulus on tumorsphere formation by breast cancer cells and maintenance of CSCs in an inert microenvironment without the interference of other factors. In that regard, 4T1 mouse breast cancer cells were encapsulated in inert polyethylene glycol diacrylate hydrogels and the effect of matrix modulus on tumorsphere formation and expression of CSC markers was investigated. The gel …
The Role Of Filler-Matrix Interaction On Viscoelastic Response Of Biomimetic Nanocomposite Hydrogels, Alireza Sarvestani, Xuezhong He, Esmaiel Jabbari
The Role Of Filler-Matrix Interaction On Viscoelastic Response Of Biomimetic Nanocomposite Hydrogels, Alireza Sarvestani, Xuezhong He, Esmaiel Jabbari
Esmaiel Jabbari
The effect of a glutamic acid (negatively charged) peptide (Glu6), which mimics the terminal region of the osteonectin glycoprotein of bone on the shear modulus of a synthetic hydorgel/apatite nanocomposite, was investigated. One end of the synthesized peptide was functionalized with an acrylate group (Ac-Glu6) to covalently attach the peptide to the hydrogel phase of the composite matrix. The addition of Ac-Glu6 to hydroxyapatite (HA) nanoparticles (50 nm in size) resulted in significant reinforcement of the shear modulus of the nanocomposite (~100% increase in elastic shear modulus). The reinforcement effect of the Glu6 peptide, a sequence in the terminal region …