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The Moderating Role Of Cost And Convenience On The Relationship In The Utaut Model To Adopt E- Payment Services, Essia Ries Ahmed, Brahim Zirari, Imane Tabet Derraz Aug 2024

The Moderating Role Of Cost And Convenience On The Relationship In The Utaut Model To Adopt E- Payment Services, Essia Ries Ahmed, Brahim Zirari, Imane Tabet Derraz

Journal of International Technology and Information Management

Many emerging economies are on the brink of a major digital revolution as a result of the disruptive and game-changing wave of digitization that aims to create a financial ecosystem that will make the transition from a cash-based economy to a cashless (digital) economy the easiest way by making reliable and secure networks, Seamless payment solutions, ensuring large transactions at lightning speeds are a reality. Most studies using UTAUT are cross-sectional, capturing data at a single point in time. Longitudinal studies are needed to observe changes in behavioural intention and actual adoption of e-payment services over time, particularly in response …


Does Personality Traits And Security Habits Influence Security Of Personal Identification Numbers? The Context Of Mobile Money Services In Tanzania., Daniel Ntabagi Koloseni Jan 2024

Does Personality Traits And Security Habits Influence Security Of Personal Identification Numbers? The Context Of Mobile Money Services In Tanzania., Daniel Ntabagi Koloseni

Journal of International Technology and Information Management

Security is an important ingredient in financial transactions; as such, it is imperative that attention should be paid to enhancing the security habits and user behaviours of mobile payment services. Establishing a link between security habits, personality characteristics, and security behaviours provides a new dimension to studying security behaviours regarding mobile money services. Therefore, this study investigates how personality traits affect security behaviours and habits and how security habits mediate the link between personality traits and PIN security practices. The study found that conscientiousness, openness to experience, extroversion and security habits influence PIN security practices, while conscientiousness, agreeableness, and neuroticism …


An Empirical Study To Understand The Role Of Institution-Based Trust And Its Antecedents In Iot Adoption By Individuals, Anupam Kumar Nath, Amit Kumar Nath Jan 2024

An Empirical Study To Understand The Role Of Institution-Based Trust And Its Antecedents In Iot Adoption By Individuals, Anupam Kumar Nath, Amit Kumar Nath

Journal of International Technology and Information Management

ABSTRACT

The Internet of Things (IoT) enables the connection between humans, physical objects, and cyber objects, resulting in monitoring, automation, and decision-making capabilities. This connection can be complex and lead to uncertainty for individuals before adopting IoT technology. To address this, we conducted research on the role of Institution-based trust in the context of IoT adoption. Our model for IoT adoption is based on existing literature and includes the components of Institution-based trust and its antecedents. Through empirical testing, we confirmed that Institution-based trust positively affects IoT adoption at the individual level. Additionally, we found that User confirmation/disconfirmation and familiarity …


Competencies And Capabilities As Determinants Of Digital Entrepreneurship: An Empirical Validation, Arvind Gudi, Ravi Chinta, Alan Jin Jan 2024

Competencies And Capabilities As Determinants Of Digital Entrepreneurship: An Empirical Validation, Arvind Gudi, Ravi Chinta, Alan Jin

Journal of International Technology and Information Management

This study aims to examine the influence of digital competencies and awareness of digital capabilities on digital entrepreneurial drive in the pre-startup stages of hi-tech businesses. Based on primary data from a sample of 357 respondents, we tested the hypothesized relationships for direct and interactive effects on digital entrepreneurial drive. Our results show that digital competencies and awareness of digital capabilities influence entrepreneurial aspiration and commitment in the pre-startup phase. We use the digital entrepreneurship framework by Recker and von Briel (2019) as the theoretical foundation and demonstrate a novel approach to expand the dimensions of digital enabler, digital outcome, …


Short-Term Prediction Of Icu Admission For Covid-19 Inpatients, Yoon Sang Lee, Riyaz T. Sikora Jan 2023

Short-Term Prediction Of Icu Admission For Covid-19 Inpatients, Yoon Sang Lee, Riyaz T. Sikora

Journal of International Technology and Information Management

Since the COVID-19 outbreak, many hospitals suffered from a surge of some high-risk inpatients needing to be admitted to the ICU. In this study, we propose a method

predicting the likelihood of COVID-19 inpatients’ admission to the ICU within a time frame of 12 hours. Four steps, the Bayesian Ridge Regression-based missing value imputation, the synthesis of training samples by the combination of two rows (the first and another row) of each patient, customized oversampling, and XGBoost classifier, are used for the proposed method. In the experiment, the AUC-ROC and F-score of our method is compared with those of other …


Learning Outcomes And Learner Satisfaction: The Mediating Roles Of Self-Regulated Learning And Dialogues, Sean Eom, Nicholas Jeremy Ashill Jan 2023

Learning Outcomes And Learner Satisfaction: The Mediating Roles Of Self-Regulated Learning And Dialogues, Sean Eom, Nicholas Jeremy Ashill

Journal of International Technology and Information Management

The interdependent learning process is regarded as a crucial part of e-learning success, but it has been largely ignored in e-learning empirical research. Grounded in constructivist and social constructivist theory, we present and test an e-learning success model consisting of eight e-learning critical success factors (CSF) derived from constructivist and social constructivist models. Three hundred seventy-two on-line students from a Midwestern university in the United States participated in the survey. The data collected from the survey was used to examine the partial least squares structural equation model. The results highlight the importance of self-regulated learning and dialogical processes to explain …


Digital Collectibles: Exploring Non-Fungible Tokens (Nfts) Through Twitter Messages, Peter Haried, James Murray Jan 2023

Digital Collectibles: Exploring Non-Fungible Tokens (Nfts) Through Twitter Messages, Peter Haried, James Murray

Journal of International Technology and Information Management

The growing popularity of non-fungible tokens (NFTs) has created a new digital collectibles asset class and market. NFTs are unique digital tokens built on blockchain technology that can represent anything from art, property rights, certificates of authentication to sports collectibles. The use of blockchain provides the framework for digital ownership and brings the notion of scarcity to the digital NFT asset class. With the emerging NFT market and growing consumer base little work has investigated the factors behind NFT interest and participation. Using a dataset of 26,444 tweets on NBA Top Shot, one of the largest and most popular NFT …


Determinants Of Continuance Intention To Use Mobile Wallets Technology In The Post Pandemic Era: Moderating Role Of Perceived Trust, Shailja Tripathi Jan 2023

Determinants Of Continuance Intention To Use Mobile Wallets Technology In The Post Pandemic Era: Moderating Role Of Perceived Trust, Shailja Tripathi

Journal of International Technology and Information Management

The Covid-19 pandemic amplified the volume and importance of mobile payments using digital wallets and placed a basis for their continued adoption. The objective of the study is to formulate and test a comprehensive model by integration of the technology acceptance model (TAM) and expectation confirmation model (ECM) with the addition of three constructs, namely perceived trust, perceived risk, and subjective norm, to identify the determinants of continuance intention to use mobile wallets. Questionnaire-based survey method was used to gather the data from 550 users having experience using mobile wallets for more than six months. The data were analyzed using …


Acceptance Of Interoperable Electronic Health Record (Ehrs) Systems: A Tanzanian E-Health Perspective, Emmanuel Mbwambo, Herman Mandari Jan 2023

Acceptance Of Interoperable Electronic Health Record (Ehrs) Systems: A Tanzanian E-Health Perspective, Emmanuel Mbwambo, Herman Mandari

Journal of International Technology and Information Management

The study assessed factors that influence the acceptance of interoperable electronic Health Records (EHRs) Systems in Tanzania Public Hospitals. The study applied a hybrid model that combined the Technology Acceptance Model (TAM) and Technology-Organization-Environment (TOE). Snowball sampling technique was applied and a total of 340 questionnaires were distributed to selected clinics, polyclinics and hospitals, of which 261 (77%) received questionnaires were considered to be valid and reliable for subsequent data analysis. IBM SPSS software version 27.0 was employed for data analysis. Findings indicated that relative advantage, compatibility, management support, organizational competency, training and education, perceived ease of use, perceived usefulness, …


Evaluating The Factors Influencing Alignment Of It And Business In A Cloud Computing Environment, Dr. Shailja Tripathi Jan 2022

Evaluating The Factors Influencing Alignment Of It And Business In A Cloud Computing Environment, Dr. Shailja Tripathi

Journal of International Technology and Information Management

Aligning IT with business strategically is the recent area of attention among researchers and practitioners because of its potential impact on organizational performance. Currently, large numbers of enterprises are migrating towards cloud computing as on-premise implementation of Information technology (IT) infrastructure is expensive. The purpose of this research is to examine the factors that influence the alignment of IT and business in cloud computing environment. Therefore, this study used the Strategic Alignment Maturity (SAM) model as a framework to validate the evolution of IT-business alignment in a cloud computing platform. A questionnaire-based survey method was employed for data collection. The …


Examining Factors Influencing Intention To Use M-Health Applications For Promoting Healthier Life Among Smartphone Users In Tanzania, Herman Mandari, Mahija Yahaya Jan 2022

Examining Factors Influencing Intention To Use M-Health Applications For Promoting Healthier Life Among Smartphone Users In Tanzania, Herman Mandari, Mahija Yahaya

Journal of International Technology and Information Management

Deaths related with Non-Communicable Diseases (NCDs) have recently increases, similarly, development of mobile technologies have paved a way in which Smartphone users can use m-health applications to address high level of sedentary behaviours that relates to negative health consequences. Therefore, this study was conducted to examine factors which may influence generation Y who are Smartphone users to adopt m-health applications in controlling NCDs in Tanzania. TAM theory was extended with awareness, trust and perceived cost to develop a research conceptual model of this study. Google form was used to developed online questionnaire which was distributed through social media platforms to …


E-Payment Adoption In Saudi Arabia, Alexander N. Chen, Joseph Y. Thomas, Mark E. Mcmurtrey Ph.D., Michael E. Ellis Jan 2022

E-Payment Adoption In Saudi Arabia, Alexander N. Chen, Joseph Y. Thomas, Mark E. Mcmurtrey Ph.D., Michael E. Ellis

Journal of International Technology and Information Management

Internet technology has influenced banking systems because of its capability to enhance the performance of financial operations. Several factors influence the adoption of new technology within the financial industry. Namely the customers’ perception of benefit, quality, Ease of Use, Security, Self-Efficacy, and Trust. However, various cultures and geopolitical issues influence technology adoption and are therefore worth further study. This paper focuses on the factors that influence the behaviors of Saudi Arabians and their adoption of e-payment systems. The paper shows the fundamental discoveries of an investigation examining the dispersion and the adoption of e-payment technology in …


Applying Technology Acceptance Model To Measure Online Student Residential Management Software Acceptance, Maka Siwale Jan 2022

Applying Technology Acceptance Model To Measure Online Student Residential Management Software Acceptance, Maka Siwale

Journal of International Technology and Information Management

The purpose of this study is to apply the technology acceptance model developed by Davis (1989) to examine the acceptance of online-based Student Residential Management Software by university on-campus housing student residents. The study examines students’ experience of using online-based software, which is believed to influence the perceived ease of use, the perceived usefulness and the behavioural intention to use such software. The results of this study were then compared to the findings of other past studies that had applied and/or tested TAM. The study participants were selected from a university in Western Australia that had implemented Student Residential Management …


Assessing Performance Impact Of Digital Transformation For Instructors In The Covid-19 Era, Shailja Tripathi Dr., Shubhangi Urkude Dr. Jan 2022

Assessing Performance Impact Of Digital Transformation For Instructors In The Covid-19 Era, Shailja Tripathi Dr., Shubhangi Urkude Dr.

Journal of International Technology and Information Management

Digital transformation has evolved as the main issue for higher education institutions (HEIs) across the globe due to the Covid-19 outbreak. The purpose of this study is to investigate the performance impacts of digital transformation for instructors of HEIs during the pandemic. The technology-to-performance chain (TPC) model pursues to predict the influence of an information system on the performance of an individual user. Hence, TPC model is used to evaluate the performance of instructors due to digital transformation in the institutions during the Covid-19 pandemic. The data is collected from instructors of higher educational institutions. Recently, partial least squares path …


Determinants Of Students’ Intention To Learn Cloud Computing, Charles Changchit, Robert Cutshall, Chuleeporn Changchit Jan 2022

Determinants Of Students’ Intention To Learn Cloud Computing, Charles Changchit, Robert Cutshall, Chuleeporn Changchit

Journal of International Technology and Information Management

The explosive growth of data and frequent application updates along with the increasing need to access data and/or applications from multiple locations has resulted in a need to improve the way data and applications are stored and served. Such a need has forced both companies and academic institutions to pay attention to cloud computing technology. Since education is a driving force for the continuous improvement of cloud computing, this study aims at identifying the factors that influence college students’ intention to learn about cloud computing technology. Specifically, the research question focuses on determining which factors drive students’ intention to learn …


Editorial Board Memberships: A Report On The Status Of The Leading Information Systems Journals, Erastus Karanja, Alisha D. Malloy Jan 2022

Editorial Board Memberships: A Report On The Status Of The Leading Information Systems Journals, Erastus Karanja, Alisha D. Malloy

Journal of International Technology and Information Management

Research journals play a significant role in the generation, dissemination, and sharing of knowledge in an academic discipline. To a great extent, the editorial board members of these research journals manage and control the generation, dissemination, and sharing of knowledge. They also act as policymakers, gatekeepers, and trendsetters. In their latter roles, editorial board members can influence several factors in a discipline; namely, the research topics, the research methods, the research scope, and whose articles are published. The primary goal of this study is to investigate and report on the status of the editorial boards memberships in a set of …


Online Discussion Forum And Pre-Migration Information Seeking: An Affordance Perspective, Daniel Gulanowski, Luciara Nardon, Michael J. Hine Jan 2022

Online Discussion Forum And Pre-Migration Information Seeking: An Affordance Perspective, Daniel Gulanowski, Luciara Nardon, Michael J. Hine

Journal of International Technology and Information Management

Potential immigrants increasingly rely on online technologies to access needed information as they have limited access to offline sources of information at the pre-arrival stage. The purpose of this paper is to investigate the role of online discussion forums in facilitating potential immigrants’ access to relevant information about the host country labor market. This paper draws on extant literature on computer-mediated communication and a qualitative content analysis of 363 forum discussions to explore the phenomenon of increased use of online forums by prospective immigrants to Canada to access relevant labor market information. We draw on existing concepts of technology affordances …


General Population Demographics Of Responses To A Nationwide Catastrophic Cyber-Attack: Exploratory Research, Garry White Jan 2021

General Population Demographics Of Responses To A Nationwide Catastrophic Cyber-Attack: Exploratory Research, Garry White

Journal of International Technology and Information Management

A national catastrophic cyber-attack is coming, just like the unpredictability of an earthquake. This exploratory research looks at the related demographics to the respond to such an attack. The responses used were Technology Optimism and Cyber Self-efficacy. The demographics studied were age, education level, surprise of the severity of an attack, gender, prior countermeasures awareness and devastation surprise. Technology Optimism and Cyber Self-efficacy showed a significant drop with the attack reading. This study’s outcomes failed to support the influence of age, gender, and prior countermeasures awareness to significant drops in Technology Optimism and Cyber Self-efficacy. Devastation surprise was significant only …


A Variation Of The Delone And Mclean Model For Collaborative Commerce Services: A Structural Equation Model, C. Christopher Lee, Pankaj Nagpal, Hyoun Sook Lim, Laura Dutil, Rebecca Lee, Youngseon Kim Jan 2021

A Variation Of The Delone And Mclean Model For Collaborative Commerce Services: A Structural Equation Model, C. Christopher Lee, Pankaj Nagpal, Hyoun Sook Lim, Laura Dutil, Rebecca Lee, Youngseon Kim

Journal of International Technology and Information Management

This study intends to provide theory-driven empirical findings of the factors affecting users’ loyalty to a collaborative commerce platform provider and further suggests that the platform loyalty lead to future extended use of collaborative commerce services. DeLone and McLean model serves as a basic framework for this study. Our variation of the model tested the impact of perceived value, relationship quality, and service quality on platform loyalty, which would influence future extended use of collaboration commerce services. Our results confirm that perceived value and platform quality were the best predictors for platform loyalty, which in turn, had a positive influence …


Auditing Algorithms: A Rational Counterfactual Framework, Seung C. Lee Jan 2021

Auditing Algorithms: A Rational Counterfactual Framework, Seung C. Lee

Journal of International Technology and Information Management

Artificial intelligence and machine learning algorithms are increasingly employed by the private and public sectors to automate simple and complex decision-making processes, but the hype has blinded people to the resulting discriminatory and biased decisions. To hold algorithms accountable for such decisions as well as to determine the underlying factors, researchers have turned to a methodological tool known as the audit study. Quite a few studies on algorithmic decision-making have made strong claims about the causality between algorithms and biased decisions. Multiple protective measures have also been enacted against the discriminatory and biased algorithmic decision-making practices. Nevertheless, they are persistent …


Transitional Challenges In Technology Adoption Among Academic Communities In Indian Higher Education Institutions, Elangovan N, Guydeuk Yeon, Sebastian Perumbilly, Sarah Hormeila Awungshi Jan 2021

Transitional Challenges In Technology Adoption Among Academic Communities In Indian Higher Education Institutions, Elangovan N, Guydeuk Yeon, Sebastian Perumbilly, Sarah Hormeila Awungshi

Journal of International Technology and Information Management

Due to the lockdown and remote working practices, academic universities around the world have been forced to adopt new technology. Online courses and exams enabled the use of new applications. During the pandemic, innovative technological adoption became faster, overriding the usual diffusion time lag. The transition was so fast that it presented a slew of new challenges to India's academic communities. An open-ended online survey was used to gather data from faculty members, students, and non-teaching staff at higher educational institutions. Several concepts about transitional challenges emerged from the qualitative data analysis. The results revealed the significant commitment needed to …


Overcoming The Downsides Of Personal Internet And Cell Phone Use In The Workplace: An Exploratory Empirical Analysis, Kaustav Misra, Michael D. Stackhouse, Arundhati Bagchi Misra, Gregory Berry Jan 2021

Overcoming The Downsides Of Personal Internet And Cell Phone Use In The Workplace: An Exploratory Empirical Analysis, Kaustav Misra, Michael D. Stackhouse, Arundhati Bagchi Misra, Gregory Berry

Journal of International Technology and Information Management

The now taken-for-granted introduction of internet usage into the workplace changed the dynamics of work, productivity, and management, and this is now further complicated by the ubiquitous availability of personal cell phones, going beyond company supplied and (partially) controlled computers with internet connections. This paper studies the connection between internet and cell phone usage by employees and firm productivity. Using primary data collected via a self-reported survey, we conduct an empirical analysis utilizing information based on firm and industry characteristics. Results indicate that the level of non-work-related internet and cell phone usage is significantly associated with firm productivity. Some of …


The Design, Development And Validation Of A Persuasive Content Generator, Sam Khataei, Michael J. Hine, Ali Arya Jan 2021

The Design, Development And Validation Of A Persuasive Content Generator, Sam Khataei, Michael J. Hine, Ali Arya

Journal of International Technology and Information Management

This paper addresses the automatic generation of persuasive content to influence users’ attitude and behaviour. Our research extends current approaches by leveraging individuals’ social media profiles and activity to personalize the persuasive content. Unlike most other implemented persuasive technology, our system is generic and can be adapted to any domain where collections of electronic text are available. Using the Yale Attitude Change approach, we describe: the multi-layered Pyramid of Individualization model; the design, development, and validation of integrated software that can generate individualized persuasive content based on a user’s social media profile and activity. Results indicate the proposed system can …


What Leads Consumers To Spread Ewom For Food Ordering Apps?, Brinda Hansraj Sampat, Kali Charan Sabat Jan 2021

What Leads Consumers To Spread Ewom For Food Ordering Apps?, Brinda Hansraj Sampat, Kali Charan Sabat

Journal of International Technology and Information Management

Restaurants are using innovative ways to engage with consumers using Food Ordering Apps (FOAs). The purpose of this article is to identify the influence of consumers’ eSatisfaction, perceived value, trust, and eLoyalty on eWOM for FOAs in India. The study also verifies if eWOM for FOAs varies based on age, gender, family size, order value, and online shopping experience. The research followed a multi-stage approach. In the first stage, an extensive literature review was conducted to identify the various factors that lead to eWOM. In the second stage, a survey was distributed among the FOA users. 375 responses were obtained. …


Integrating Voice Over Ip Solution In Ipv6 And Ipv4 Networks To Increase Employee Productivity: A Case Study Of Cameroon Telecommunications (Camtel), North-West, Lottin Cyrille Marcel Malobe, Austin Oguejiofor Amaechi Jan 2021

Integrating Voice Over Ip Solution In Ipv6 And Ipv4 Networks To Increase Employee Productivity: A Case Study Of Cameroon Telecommunications (Camtel), North-West, Lottin Cyrille Marcel Malobe, Austin Oguejiofor Amaechi

Journal of International Technology and Information Management

Telecommunications organizations have to follow the rapid innovation of technology if they want to face challenges raised by competition. The challenge to respond to the huge market demand of updated products and services from customers requires that the organization‘s working environment be equipped with tools and communication facilities that contribute to ameliorating productivity. Cameroon Telecommunications (Camtel) is facing a digital telephony and Internet Protocol strategic management challenge. Successful implementation cannot be achieved if the employees are still depending on the ageing public switched telephone network (PSTN) as their primary communication system, despite the frequent loss of dial tone experience in …


Trust And Closeness: A Mixed Method For Understanding The Relationship Of Social Network Users, Lei Yang, Xue Wang, Margaret Meiling Meiling Luo Jan 2021

Trust And Closeness: A Mixed Method For Understanding The Relationship Of Social Network Users, Lei Yang, Xue Wang, Margaret Meiling Meiling Luo

Journal of International Technology and Information Management

Mutual trust among social networks users encourages positive communications, so it is critical to study trust in the context of online social networks. In this study, we built a model to calculate trust of social media users. Data was collected from Qzone (Tencent Technology Co., Ltd.), a SN service (also known as QQ) in China. We identified 150 QQ users and 3 friends from each of the users; data of these users were collected by Python program. The relationship between trust and closeness was constructed using an ordinary least squares regression model, and the factors that influence trust between social …


Digital Divide Of Perceptions, Usage, And Purchase Items In Japanese E-Payment Adoption, Michael E. Ellis, Moe Ota, Alexander N. Chen Jan 2021

Digital Divide Of Perceptions, Usage, And Purchase Items In Japanese E-Payment Adoption, Michael E. Ellis, Moe Ota, Alexander N. Chen

Journal of International Technology and Information Management

The idea of a “digital divide” is a common issue in less developed countries but is also found in developed countries. We surveyed 151 Japanese to examine the effect of digital divide characteristics such as regional variations, age, and gender on the perception and behavior surrounding e-payments.

We find that regional difference affects Japanese perceptions, especially ease of use and trust, but not use. Also, older people are more like to use e-payment in terms of weekly frequency and amount of money spent than younger consumers. Japanese males, in general, have higher average scores in ease of use, importance of …


A Comparison Of Artificial Neural Networks And The Statistical Methods In Predicting Mba Student’S Academic Performance, Ojoung Kwon, Harry Hui Xia, Serin Zhang Jan 2021

A Comparison Of Artificial Neural Networks And The Statistical Methods In Predicting Mba Student’S Academic Performance, Ojoung Kwon, Harry Hui Xia, Serin Zhang

Journal of International Technology and Information Management

MBA has become one of the most popular and vital professional degrees internationally. The MBA program admission process’s essential task is to choose the best analysis tools to accurately predict applicants’ academic performance potential based on the evaluation criteria in making admission decisions. Prior research finds that the Graduate Management Admission Test (GMAT) and undergraduate grade point average (UGPA) are common predictors of MBA academic performance indicated by graduate grade point average (GGPA). Using a sample of 250 MBA students enrolled in a state university with AACSB accreditation from Fall 2010 to Fall 2017, we test and compare the effectiveness …


Do I Desire Chatbots To Be Like Humans? Exploring Factors For Adoption Of Chatbots For Financial Services, Moses Sugumar, Shalini Chandra Jan 2021

Do I Desire Chatbots To Be Like Humans? Exploring Factors For Adoption Of Chatbots For Financial Services, Moses Sugumar, Shalini Chandra

Journal of International Technology and Information Management

AI-powered chatbots are gaining traction across various industries, especially in the financial sector. Despite these implementations, chatbot adoption and usage among consumers is still low. Grounding on the unified theory of acceptance and use of technology 2 (UTAUT2) model and the Belief Desire Intentions (BDI) model, this study explores factors influencing the adoption of chatbots for financial sectors by emphasizing on the role of user desires in addition to human beliefs. Explicitly, the research hypothesizes the role of the humanness in chatbots influencing consumer adoption in the financial services sector. The suggested research model was tested via a sample of …


A Data Driven Approach To Profile Potential Sars-Cov-2 Drug Interactions Using Tylerade, Robert P. Schumaker, Michael A. Veronin, Trevor Rohm, Matthew Boyett, Rohit R. Dixit Jan 2021

A Data Driven Approach To Profile Potential Sars-Cov-2 Drug Interactions Using Tylerade, Robert P. Schumaker, Michael A. Veronin, Trevor Rohm, Matthew Boyett, Rohit R. Dixit

Journal of International Technology and Information Management

We use a data driven approach on a cleaned adverse drug reaction database to determine the reaction severity of several covid-19 drug combinations currently under investigation. We further examine their safety for vulnerable populations such as individuals 65 years and older. Our key findings include 1. hydroxychloroquine/chloroquine are associated with increased adverse drug event severity versus other drug combinations already not recommended by NIH treatment guidelines, 2. hydroxychloroquine/azithromycin are associated with lower adverse drug event severity among older populations, 3. lopinavir/ritonavir had lower adverse reaction severity among toddlers and 4. the combination of azithromycin, hydroxychloroquine and tocilizumab is safer than …