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Biomedical Engineering and Bioengineering

McKelvey School of Engineering Theses & Dissertations

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Machine learning

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Ultrasound Guided Diffuse Optical Tomography For Breast Cancer Diagnosis: Algorithm Development, K M Shihab Uddin May 2020

Ultrasound Guided Diffuse Optical Tomography For Breast Cancer Diagnosis: Algorithm Development, K M Shihab Uddin

McKelvey School of Engineering Theses & Dissertations

According to National Breast Cancer Society, one in every eight women in United States is diagnosed with breast cancer in her lifetime. American Cancer Society recommends a semi-annual breast-cancer screening for every woman which can be heavily facilitated by the availability of low-cost, non-invasive diagnostic method with good sensitivity and penetration depth. Ultrasound (US) guided Diffuse Optical Tomography (US-guided DOT) has been explored as a breast-cancer diagnostic and screening tool over the past two decades. It has demonstrated a great potential for breast-cancer diagnosis, treatment monitoring and chemotherapy-response prediction. In this imaging method, optical measurements of four different wavelengths are …


Improving Pure-Tone Audiometry Using Probabilistic Machine Learning Classification, Xinyu Song Aug 2017

Improving Pure-Tone Audiometry Using Probabilistic Machine Learning Classification, Xinyu Song

McKelvey School of Engineering Theses & Dissertations

Hearing loss is a critical public health concern, affecting hundreds millions of people worldwide and dramatically impacting quality of life for affected individuals. While treatment techniques have evolved in recent years, methods for assessing hearing ability have remained relatively unchanged for decades. The standard clinical procedure is the modified Hughson-Westlake procedure, an adaptive pure-tone detection task that is typically performed manually by audiologists, costing millions of collective hours annually among healthcare professionals. In addition to the high burden of labor, the technique provides limited detail about an individual’s hearing ability, estimating only detection thresholds at a handful of pre-defined pure-tone …